Novel titanocene anti-cancer drugs derived from fulvenes and titanium dichloride

Starting from 6-(p−N,N-dimethylanilinyl)fulvene (1a) or 6-(pentamethylphenyl)fulvene (1b) [1,2-di(cyclopentadienyl)-1,2-di(p−N,N-dimethylaminophenyl)ethanediyl] titanium dichloride (2a) and [1,2-di(cyclopentadienyl)-1,2-bis(pentamethylphenyl)ethanediyl] titanium dichloride (2b) and their corresponding dithiocyanato complexes (3a, 3b) were synthesized. Titanocene 2b did not show a cytotoxic effect, but when 2a was tested against pig kidney carcinoma cells (LLC-PK) or human ovarian carcinoma cells (A2780/cp70) inhibitory concentrations (IC₅₀) of 2.7 × 10⁻⁴ and 1.9 ×  10⁻⁴ M, respectively, were observed.     

Effect of photochemical oxidation on polypropylene phosphorescence

Phosphorescence from polyolefins was studied from the aspects of excitation and emission wavelength and lifetime. Effects of photochemical oxidation on polypropylene phosphorescence are discussed in contrast to the effects of thermal oxidation.     

A limiting absorption principle for Schrödinger operators with Von Neumann-Wigner type potentials

In this paper we prove the main step in establishing a limiting absorption principle for von Neumann-Wigner type Schrödinger Hamiltonians of the form –+csinb|x|/|x|+V(x), whereV(x) is a short range potential. The first fundamental step is to obtain a limiting absorption principal for the free operator –+csinb.|x|/|x|. The free operator is unitarily equivalent to a direct sum of ordinary differential operators. We obtain uniform estimates for the resolvents of these ordinary differential operators. by obtaining uniform estimates for the Weyl-Green kernels of these resolvents. In turn, these latter estimates require uniform estimates on the Wronskians of certain generalized eigen-solutions of these differential operators.This paper is dedicated to the memory of the late Professor Charles C. Conley.