Electrochemical Enzyme Immunoassay of Tumor Marker CA15-3 with Capillary Electrophoresis

CA15-3 is a circulating antigen that is relatively specific for human breast tissue. CA15-3 is significantly more sensitive than carcinoembryonic antigen in the evaluation of patients with both primary and metastatic breast cancer. CA15-3 levels are often measured by using radioimmunoassay and enzyme immunoassay (EIA) in clinic. These methods are carried out manually. Tedious processes, slow reaction, poor reproducibility are their major problems. Capillary electrophoretic immunoassay …     

AaDd型氢键流体的统计理论(Ⅰ): 几何相变

通过两种不同的统计方法研究了A_aD_d型氢键体系中的氢键对体系的一些物理化学特征的影响. 指出获得氢键簇合物数量分布函数的两种新方法, 得到该体系的平衡自由能以及氢键度与外界条件之间关系的解析表达式, 讨论了氢键的成键概率与相关热力学量的关系. 在平均场理论的框架下, 证明了非线性氢键体系中发生的溶胶-凝胶相转变是一类几何相变, 而非热力学相变. 进一步对氢键体系中此类几何相变与液-固热力学相变间的关系进行了初步探讨.     

Positional and Quantitative Characterization of the Hydroxyethyl Groups in Hydroxyethyl Starch by GC/MS or NMR

Hydroxyethyl starches (HES) have been used medically as plasma volume expanders. They are composed of a starch backbone and substituted hydroxyethyl groups. The backbone is ?(1,4)-glycosidic-linked anhydroglucose units, which has branches formed by ?(1,6)-glycosidic bonds. Hydroxyethylation can take place at the C-2, C-3 and C-6 sites of the glucose rings, as well as at the hydroxyl groups of the substituted hydroxyethyl groups. Variation of the position and quantity of the substituted …     

氢键簇生长的反应动力学和统计力学理论

分析氢键的形成机理与缩聚反应在统计意义下的相似性,以AaDd型氢键体系为例,分别应用反应动力学方法和统计力学理论研究了氢键簇的生长过程.两种方法给出的结果一致,由此说明,高分子反应统计力学理论可以用来研究氢键体系.然后,给出了AaDd型氢键体系中质子给体和受体官能团的反应程度与体系Gibbs自由能等热力学量之间的解析表达式.进一步预言一些氢键体系可以发生溶胶-凝胶相转变现象,并给出可以描述相变过程的广义标度律.     

_f-A_aD_d氢键体系的统计特征

基于氢键的形成和缩聚反应机理在统计意义下的相似性,利用高分子反应统计理论和反应动力学理论对氢键溶液的一个模型体系进行了相关讨论.给出了体系的溶胶分数和发生溶胶-凝胶相变的条件,指出质子受体基团间的竞争作用对溶胶凝胶相变点的影响,进而讨论了体系的数量分布函数和相关问题.     

Study on the Surface Photovoltage and Fluorescence Properties of N, N-Bis(4-aminopheny)-1, 4 quinonenediimine Doped with H_4SiW_(12)O_(40)

Polyaniline, especially its acid-dopping composite material, is a kind of important photoelectric material due to its potential application in many fields1~3. However, it seems to be a problem that the polymers exhibit several deficiencies, including chemical and structural imperfections as a result of mislinkage, saturated sites, molecular weight distribution, the presence of the end groups and conformation defects. All of these defects affect the device efficiency and make it difficult to …     

Inhibitory Effect of Anti-HER-2 Anti-CD3 Bi-specific Antibody on the Growth of Gastric Carcinoma

Introduction Gastriccancerisoneofthemostcommonlyen counteredmalignantdiseasesworldwide,especiallyin AsiaandAfrica[1].Thecombinationofoperation,chemotherapyandradiotherapyisusedfortreatinggas triccarcinoma.However,the5yearsurvivalrateof patientsofgastricca…     

Fabrication and characterization of multidimensional tungsten oxide networks

Approaches for preparation of porous oxides with different length scales are currently available[1?3]. Materials with hierarchical pore systems at two or three different length scales have also been prepared[4?7]. Such materials are important both for the…     

Carbon Fiber-gold/mercury Dual-electrode Detection for Capillary Electrophoresis

Capillary electrophoresis (CE) has become a useful and powerful separation technique and has many applications. Electrochemical detection (ED) has been shown to be one of the most sensitive detection techniques available for use in CE. Dual-electrode detection can expand the applicability of CE-ED1-5, the materials such as gold/mercury1,3, carbon fiber2, Pt4 and Au3,5 have been used for the two electrodes in dual-electrodes. As is well known, the electrochemical response of different c…     

Novel Reaction of Nitroxide with Hantzsch Dihydropyridines

Nitroxides have been found to be the intermediate in the in vivo metabolism of hydroxamic acid, a well-known biological molecule1. Structural modification of some antitumor drugs by introducing nitroxides can lower toxicity remarkably with retention or even increase of the antitumor activity2. Furthermore, the use of nitroxides as spin probes makes it possible to get information regarding the microenvironment of the reaction. 4-Substituted Hantzsch 1,4-dihydropyridines (DHP) are analogs …