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121.
Ming-Qian  Sun  Jian-Xun  Liu  Lan  Miao  Jin  Cao  Cheng-Ren  Lin  Lei  Li  Jianxun  Ren 《Chromatographia》2012,75(9-10):491-497

In this study, serum metabolic profiles of mini-pigs with atherosclerosis (AS) were analyzed by LC–TOFMS. Partial least-squares to latent structure-discriminant analysis and orthogonal projection to latent structure-discriminant analysis were used for group differentiation and selection of potential biomarkers. The mini-pig disease models were constructed by feeding a high-fat diet and inducing coronary injury, in accordance with the mechanism of AS pathogenesis. To characterize the development of AS, serum samples were collected and analyzed at two time points (two and ten weeks). Separate distinct clustering of results from normal and model mini-pigs could be observed for both the two and ten-week samples. With the development of AS, the metabolism of the model mini-pigs was more substantially disturbed. Major metabolites contributing to the discrimination were fatty acids, lysophosphatidylcholines, and bile acids. These potential biomarkers are related with inflammation, oxidative stress, and abnormal lipid and energy metabolism.

  相似文献   
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The sorption equilibria of carbon dioxide on three types of silica gel (SG) with different pore size distributions in the presence of water were studied experimentally using a volumetric method at 275?K with pressures from 0 to 3.7?MPa. Both the pore size distribution of the silica gel and the quantity of pre-sorbed water impact the formation of the CO2 hydrates. For wet silicon gel A(SG-A) with water loading ratio of 0.75, the highest CO2 sorption was about 2.5?mmol of CO2 per gram of dry sorbent at 275?K. Similarly, the highest sorption was about 2.7?mmol for wet SG-B with R w =0.81. However, CO2 hydrate did not form on the wet surface of SG-C due to its large pore sizes.  相似文献   
124.
Many transport processes on network depend crucially on the underlying network topology. In this paper, we propose a model to generate correlated scale free transportation networks with community structure by considering the mechanisms of dynamical network evolution and rewiring links. With the introduction of congestion effects, we investigate the performance and carrying capacity of this network. The results show that congestion in the uncorrelated network is more serious than the assortative or disassortative ones. Therefore, the correlated network with communities can bear much more traffic flow. In addition, the networks with lager modularity can enhance the transportation efficiently.  相似文献   
125.
Pyridinium 1,4-zwitterionic thiolates were applied to a formal [3 + 2] annulation reaction with modified activated alkynes, affording various tetrasubstituted thiophenes with aryl, alkenyl, alkyl or silyl group at the special position. The structural modification of alkyne substrates enabled the synthesis of diverse thiophenes to be achieved using the pyridinium 1,4-zwitterionic thiolates as the sulfur-containing building blocks. This approach is metal-free and catalyst-free.  相似文献   
126.
何静婧  刘玮  李志国  李博研  韩安军  李光旻  张超  张毅  孙云 《物理学报》2012,61(19):198801-198801
在柔性聚酰亚胺衬底上低温制备Cu(In,Ga)Se2薄膜太阳能电池, Na的掺入会改善电池特性, 但不同的掺Na工艺对Cu(In,Ga)Se2薄膜和器件特性的改善机理不同. 本实验通过对比前掺NaF和后掺NaF工艺发现, 在前掺Na工艺下, 由于Na始终存在于Cu(In,Ga)Se2薄膜生长过程中, Na存在于多晶 Cu(In,Ga)Se2 薄膜晶界处, 起到了扩散势垒的作用, 导致晶粒细碎、加剧两相分离, 同时减小了施主缺陷的形成概率; 而在后掺Na工艺下, 掺入的Na对薄膜的结构及生长不产生影响, 仅仅起到了钝化施主缺陷、改善薄膜缺陷态的作用. 同时, 研究表明, 后掺Na工艺中, NaF必须依靠外界能量辅助才能扩散进Cu(In,Ga)Se2内部, 实验结果证实, 只有衬底温度达到350 ℃以上时, 掺入的NaF才能较好地改善薄膜特性. 最终经掺Na工艺的优化, 得到低温工艺制备的柔性聚酰亚胺衬底器件效率达10.4%.  相似文献   
127.
The kinetic theory based on the expansion of local field in the guiding center coordinate system, presented by paper[1]–[3], has successfully developed into a theoretical system. The mathematical background and physical explanation of setting up the guiding center coordinate system is expounded in the paper. By using the methods of the guiding center and waveguide coordinate systems respectively, the same dispersion equations for interaction of an axially symmetrical single momentum electron beam with TEmn field in the circular waveguide are rigorously derived. A number of mistakes in paper[4] are indicated as well.  相似文献   
128.
测量了在蓝宝石衬底上气相外延生长GaN的拉曼散射谱.除观察到已被确认的两个E2,一个A1(TO)和一个E1(TO)声于振动以外,在734±3cm-1处观察到一个散射峰且从实验上确认其为GaN的纵向光学声子模E1(LO).而且发现其强度与外延层晶体质量密切相关.A1(TO)和高频E2散射峰相对强度变化显示不同生长条件引起的外延层质量的变化.  相似文献   
129.
The K=3/2 1 T rotational band has been identified in99Y with a band-head energy of 536 keV. This result is in contradiction with previously reported data, but is in agreement with predictions of the IBFM/PTQM model.  相似文献   
130.
The covariant-derivative regularization program is discussed ford-dimensional gauge theory coupled to fermions in an arbitrary representation.  相似文献   
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