全文获取类型
收费全文 | 206篇 |
免费 | 5篇 |
国内免费 | 1篇 |
专业分类
化学 | 131篇 |
晶体学 | 2篇 |
力学 | 2篇 |
数学 | 35篇 |
物理学 | 42篇 |
出版年
2023年 | 2篇 |
2022年 | 2篇 |
2021年 | 4篇 |
2020年 | 5篇 |
2019年 | 4篇 |
2018年 | 2篇 |
2016年 | 7篇 |
2015年 | 4篇 |
2014年 | 5篇 |
2013年 | 8篇 |
2012年 | 12篇 |
2011年 | 9篇 |
2009年 | 2篇 |
2008年 | 4篇 |
2007年 | 8篇 |
2006年 | 9篇 |
2004年 | 6篇 |
2003年 | 2篇 |
2002年 | 3篇 |
2001年 | 2篇 |
2000年 | 2篇 |
1998年 | 2篇 |
1997年 | 6篇 |
1995年 | 2篇 |
1993年 | 3篇 |
1992年 | 2篇 |
1991年 | 7篇 |
1990年 | 6篇 |
1989年 | 3篇 |
1987年 | 3篇 |
1986年 | 3篇 |
1985年 | 4篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1982年 | 5篇 |
1981年 | 3篇 |
1980年 | 4篇 |
1979年 | 7篇 |
1978年 | 4篇 |
1977年 | 6篇 |
1976年 | 5篇 |
1975年 | 3篇 |
1974年 | 3篇 |
1973年 | 4篇 |
1970年 | 4篇 |
1965年 | 2篇 |
1925年 | 1篇 |
1919年 | 2篇 |
1902年 | 1篇 |
1889年 | 1篇 |
排序方式: 共有212条查询结果,搜索用时 15 毫秒
211.
Kareis CM Lapidus SH Her JH Stephens PW Miller JS 《Journal of the American Chemical Society》2012,134(4):2246-2254
The aqueous reaction of Mn(II) and NaCN leads to the isolation of the 3-D Prussian blue analogue (PBA) Na(2)Mn[Mn(CN)(6)]·2H(2)O (1·H(2)O), which under careful dehydration forms 1. 1·H(2)O is monoclinic [P2(1)/n, a = 10.66744(32) ?, b = 7.60223(23) ?, c = 7.40713(22) ?, β = 92.4379(28)°], while 1 is rhombohedral [R ?3, a = 6.6166(2) ?, c = 19.2585(6) ?], and both structures are atypical for PBAs, which are typically face centered cubic. Most notably, the average ∠Mn-N-C angles are 165.3(3)° and 142.4(4)° for 1·H(2)O and 1, respectively, which are significantly reduced from linearity. This is attributed to the ionic nature of high-spin Mn(II) accommodating a reduced ∠Mn-N-C to minimize void space. Both 1 and 1·H(2)O magnetically order as ferrimagnets below their ordering temperature, T(c), of 58 and 30 K, respectively, as determined from the average of several independent methods. 1 and 1·H(2)O are hard magnets with 5 K coercive fields of 15,300 and 850 Oe, and remnant magnetizations of 9075 and 102 emu·Oe/mol, respectively. These data along with previous T(c)'s reported for related materials reveal that T(c) increases as the ∠Mn-N-C deviates further from linearity. Hence, the bent cyanide bridges play a crucial role in the superexchange mechanism by increasing the coupling via shorter Mn(II)···Mn(II) separations, and perhaps an enhanced overlap. 相似文献
212.
Saul Vislei Simes da Silva Orlando Maia Barboza Jssica Teles Souza rica Novaes Soares Cleonice Creusa dos Santos Luciano Vasconcellos Pacheco Ivanilson Pimenta Santos Tatiana Barbosa dos Santos Magalhes Milena Botelho Pereira Soares Elisalva Teixeira Guimares Cssio Santana Meira Silvia Lima Costa Victor Digenes Amaral da Silva Loureno Luís Botelho de Santana Aníbal de Freitas Santos Júnior 《Molecules (Basel, Switzerland)》2021,26(22)
Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural modification in Q by acetylation, thus, obtaining the quercetin pentaacetate (Q5) analogue, in order to investigate the biological potentials (antioxidant, antileishmania, anti-inflammatory and cytotoxicity activities) in cell cultures. Q5 was characterized by FTIR, 1H and 13C NMR spectra. The antioxidant potential was evaluated against the radical ABTS•+. The anti-inflammatory potential was evaluated by measuring the pro-inflammatory cytokine tumor necrosis factor (TNF) and the production of nitric oxide (NO) in peritoneal macrophages from BALB/c mice. Cytotoxicity tests were performed using the AlamarBlue method in cancer cells HepG2 (human hepatocarcinoma), HL-60 (promyelocytic leukemia) and MCR-5 (healthy human lung fibroblasts) as well as the MTT method for C6 cell cultures (rat glioma). Q and Q5 showed antioxidant activity of 29% and 18%, respectively, which is justified by the replacement of hydroxyls by acetyl groups. Q and Q5 showed concentration-dependent reductions in NO and TNF production (p < 0.05); Q and Q5 showed higher activity at concentrations > 40µM when compared to dexamethasone (20 µM). For the HL-60 lineage, Q5 demonstrated selectivity, inducing death in cancer cells, when compared to the healthy cell line MRC-5 (IC50 > 80 µM). Finally, the cytotoxic superiority of Q5 was verified (IC50 = 11 µM), which, at 50 µM for 24 h, induced changes in the morphology of C6 glioma cells characterized by a round body shape (not yet reported in the literature). The analogue Q5 had potential biological effects and may be promising for further investigations against other cell cultures, particularly neural ones. 相似文献