The influence of the first integrals and the rolling resistance model on tippe top inversion

Nonlinear Dynamics - In this paper, we analyze the effect which the choice of a friction model has on tippe top inversion in the case where the resulting action of all dissipative forces is...     

Dispersive correction for the second- and the third-order nonlinear terms of the electrical energy density for a light-dielectric system

Optical and Quantum Electronics - Classification of hyperspectral image (HSI) is widely used for the study of remotely sensed images. Convolutional Neural Networks (CNNs) are one of the most...     

INFLUENCE OF THE INITIAL ROUGHNESS OF INTERFACES ON THE INSTABILITY DEVELOPMENT AFTER SHOCK-WAVE PASSAGE

Journal of Applied Mechanics and Technical Physics - Turbulent mixing at interfaces of three-layer gas systems after shock-wave passage has been studied. The influence of the initial roughness of...     

Self-Consistent Stationary Distributions of the Electric Field and Plasma Density in the Process of Ionization Self-Channeling of Quasielectrostatic Waves

Radiophysics and Quantum Electronics - We find self-consistent stationary distributions of the electric field and plasma density in the process of ionization self-channeling of quasielectrostatic...     

A Variational Finite Element Discretization of Compressible Flow

Foundations of Computational Mathematics - We present a finite element variational integrator for compressible flows. The numerical scheme is derived by discretizing, in a structure-preserving way,...     

Robustness of the Spin-Navigator Based Method for the Manipulation of the Beam Polarization Axis in a Spin-Transparent Storage Ring

Physics of Atomic Nuclei - We have investigated the robustness of the spin-navigator based method for manipulating the beam polarization to bend magnet installation errors. Toward that end,...     

Topical application of zein-silk sericin nanoparticles loaded with curcumin for improved therapy of dermatitis

Atopic dermatitis is characterized by leukocyte migration into the skin dermis and typically driven by excessive chemokine production at the site of inflammation. Conventional topical formulations such as gels, creams, and ointments are insufficient for this treatment because of low penetration of drug molecules into the targeted skin tissues. Herein, using a simple, green, sustainable strategy, we have developed novel primary zein nanoparticles embedded in curcumin (Cur) and coated with silk sericin (ZHSCs) for the topical delivery of Cur to penetrate into the dermis and exercise anti-dermatitis effects on the lesion with minimal side-effects. Transdermal delivery experiments and porcine skin fluorescence imaging indicated that ZHSCs facilitate the penetration of Cur across the epidermis layer of skin to reach deep-seated sites. Notably, ZHSCs = 1:0.25 (zein-to-silk sericin mass ratios of 1:0.25) markedly elevated the skin permeability and cumulative turnover of Cur transferred, which were provided a greater than a 3.8-fold increase relative to free Cur. The special nanoparticles of ZHS = 1:0.25 possessed the deepest localization depth and experience a transition of the particle structure and core-shell separation after penetrating into the dermis of skin. In a cell model of dermatitis induced by tumor necrosis factor α/interferon γ co-stimulation, compared with free Cur, Cur-loaded ZHS nanoparticles down-regulated the generation of inflammatory cytokines and chemokines in keratinocytes through suppression of the nuclear translocation of NF-κBp65 and hence exerted an anti-dermatitis effect. This strategy may provide new avenues and direction for the demanding issues of valid topical delivery systems.     

Crystallographic Parameters of Special Grain Boundaries in Multicrystalline Silicon

Crystallography Reports - The orientation of grains and the special boundaries formed by them in multicrystalline silicon has been studied by electron backscattered diffraction. It is found that...     

Neutron Spectroscopy: The Initial Steps of Development in Our Country and Several Achievements

Crystallography Reports - Some questions related to the establishment, development, and prospects of physical studies using inelastic thermal-neutron scattering are briefly reviewed. The directions...