SYNTHESIS AND REACTIONS OF HALO DERIVATIVES OF 4-ISOPROPYL-2H-1,4-THIAZIN-3-ONE

Abstract

Reaction of 4-isopropyl-2H-1,4-thiazin-3-one 1 (R [dbnd] i-Pr) with N-chloro- and N-bromosuccinimide occurred exclusively at the 6-position to give 6-chloro and 6-bromo derivatives of 1 (R [dbnd] i-Pr), respectively, in high yield, in sharp contrast to the 2-aroyloxylation by benzoyl peroxide or m-chloroperbenzoic acid reported earlier.² Reaction of 1 (R [dbnd] i-Pr) with methanesulfonyl chloride in the presence of aluminum chloride afforded an addition compound, 4-isopropyl-5,6-dichloro-1,4-tetrahydrothiazin-3-one. The 2-chloro derivative 6 of 1 (R [dbnd] i-Pr) was successfully prepared by hydrolysis of the 2-m-chloroben-zoyloxy derivative of 1 (R [dbnd] i-Pr) followed by treatment with thionyl chloride. Derivative 6 reacted readily under mild conditions with water, alcohols, thiols, ammonia and amines to give various 2-substituted compounds of 1 (R [dbnd] i-Pr). With phenol as a nucleophile, 1 (R [dbnd] i-Pr) reacted exclusively at the para position. Reaction at carbon atoms also occurred with N,N-dimethylaniline and 2,6-xylidine.     

High-resolution spectroscopy of low-energy electrons emitted in nuclear transformations

Some measurements of low-energy converslon electrons and photoelectrons are presented. The results were obtained using electrostatic cylindrical mirror analyzers.     

Experimental studies of emission of highly charged Au-ions and of X-rays from the laser-produced plasma at high laser intensities

Au ions with maximum charge states 58+ and with the kinetic energy in a region of ∼100 MeV were recorded. The influence of various experimental conditions is presented and discussed.     

What atomic model should be used in internal conversion calculations?

From a measurement of the impact parameter dependence of positron production in heavy ion-atom collisions the relation between the average impact parameter and the energy transfer could be calibrated.     

Internal conversion of valence shell electrons: Measurement and analysis for the 10.84 keV transition in206Bi

Conversion electrons of the 10.84 keV transition in²⁰⁶Bi were measured with the iron-free magnetic spectrometer. The conversion line of the valence shell was observed to be narrower than those of the inner ones. The computer program which optimizes the line profiles given numerically is outlined and used for the spectrum analysis. The studied transition was proved to be pure M1 with the nuclear structure parameterλ=1.7±0.7. The internal conversion coefficients were calculated using the relativistic Hartree-Fock model for neutral atoms as well as various isolated ions. Altogether, 15 different valence-shell configurations were considered. The prediction for the 6s ₁ ^2/2 configuration (Bi³⁺) is in accord with the measured conversion intensities. This is consistent with probable chemical form Bi₂O₃ of bismuth atoms in the radioactive source.