Synthesis of new sulfinyl derivatives of 4,5-diphenyl-4H-1,2,4-triazoles

Russian Journal of Organic Chemistry -     

New synthesis of alkane- and arylsulfonyl chlorides by oxidation of thiols and disulfides with chlorine dioxide

Russian Journal of Organic Chemistry -     

Chlorine dioxide in chemo- and stereoselective oxidation of sulfides

Data on oxidation of alkyl-, phenyl-, benzyl-, oxo-, and terpenyl-substituted and nitrogen-containing heterocyclic sulfides with chlorine dioxide are reviewed. The oxidation is highly chemoselective and moderately stereo- and enantioselective.     

One-Pot Synthesis and Asymmetric Oxidation of 2-Nitro-4-(Trifluoromethyl)Benzene Containing Sulfides

Abstract

An efficient one-pot method for the preparation of 2-nitro-4-(trifluoromethyl)benzene containing sulfides from 1,1′-disulfanediylbis[2-nitro-4-(trifluoromethyl)benzene] is proposed. The corresponding enantiomerically enriched sulfoxides with up to 78% enantiomeric excess are prepared by the asymmetric oxidation of sulfides using a modified Sharpless method. The yield of sulfoxides is shown to decrease with an increase in the bulk of the aliphatic group and with a decrease of the inductive effect of the hydrocarbonic moiety on the sulfur atom.

Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

GRAPHICAL ABSTRACT      

Path toward fast calculations in quantum scattering theory

Finite-dimensional approximations for scattering theory operators and for the Lippmann-Schwinger equation are obtained by going over to a basis of stationary wave packets. A multidimensional wave-packet basis is used for the first time, which allows to avoid expanding wave functions in partial waves and thereby to reduce substantially, at intermediate energies, the dimensions of the basis space used. In this wave-packet subspace, a finite-dimensional analytic representation of the free-particle Green’s function is obtained, which simplifies essentially solving respective equations. The possibility of a massive-parallel treatment of the resulting equations is shown.     

Oxidation by chlorine dioxide of methionine and cysteine derivatives to sulfoxides

Methionine and cysteine derivatives were oxidized asymmetrically by chlorine dioxide to sulfinyl derivatives. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 608–610, November–December, 2008.     

Asymmetrical oxidation of menthone dithiolane

Asymmetrical oxidation was performed of menthone dithiolane obtained in 95–98% yield by condensation of menthone with 1,2-ethanedithiol in the presence of boron trifluoride etherate. 6-Isopropyl-9-methyl-1,4-dithiaspiro[4,5]decane-1,4-dioxide (yield 5–55%) and 6-isopropyl-9-methyl-1,4-dithiaspiro[4,5]-decane-1,1,4-trioxide (yield 65–70%) were synthesized. Chemical structures of compounds obtained were proved by XRD analysis, NMR and IR spectroscopy.     

Asymmetric oxidation of hetaryl neomenthyl sulfides

Previously unknown diastereoisomeric sulfoxides were synthesized by asymmetric oxidation of 2-neomenthylsulfanyl-substituted 1H-imidazole, 1-methyl-1H-imidazole, and 1H-benzimidazole.     

Synthesis and reduction of new sulfinimines with isobornane structure

Synthesis of sulfenimines proceeding from isobornanethiol with yields up to 78% was performed. They were oxidized to diastereomeric isobornylsulfinimines and the latter were reduced to N-substituted isobornylsulfinamides in high yields.     

Phase diagram of an iodine-potassium iodide-water-ethanol system at 25°C

Phase equilibriums are studied in the isothermal-isobaric sections of the phase diagram of a fourcomponent iodine-potassium iodide-water-ethanol system at 25°C and atmospheric pressure. The compositions of the solvent at which it exhibits the greatest ability to dissolve iodine are established. It is shown that in all the investigated sections, there is three-phase eutonic equilibrium with potassium iodide and crystalline iodine as the solid phases. It is revealed that in the sections containing 30 and 50% of ethanol, potassium iodide serves as the salting in agent for crystalline iodine, due to the formation of polyiodide complexes of various composition in the studied system.