Microwave-assisted Preparation of Temperature Sensitive Poly（N-isopropylacrylamide） Hydrogel with Improved Responsive Properties

Poly(N-isopropylacrylamide) (PNIPAM) hydrogel, which is insoluble but shrinkable or swellable in aqueous media when temperature rises or drops across 33oC1,2, has been extensively studied due to its potential applications in the fields of controlled drug …     

An affinity-based probe for the proteomic profiling of aspartic proteases

We have developed an affinity-based probe for the proteomic profiling of aspartic proteases. Our probe was shown to be selective towards aspartic proteases over other proteins. It was also shown that the strategy may be used to label selectively aspartic proteases in the presence of a large excess of other proteins, thus making it useful for future proteome profiling experiments.     

丙烷脱氢制丙烯研究进展

介绍了丙烷脱氢制丙烯的研究现状。包括丙烷催化脱氢的热力学、脱氢技术丙烷在膜反应器中脱氢及以氧气和二氧化碳作氧化剂的丙烷氧化脱氢。     

A Novel Photoproduct of 1, 3-Dimethyluracil in Phosphate Buffered-saline

1, 3-Dimethyluracil （DMU） in phosphate buffered-saline （PBS, pH=8） was irradiated by a medium pressure mercury lamp （MPML） and produced a novel compound C6H9N2O6P. The composition and structure of the compound has been identified by elemental analysis, EIMS, UV, IR, ^1H and ^31P-NMR.     

2-取代亚肼基-1,3-二硫杂环戊烷类化合物的合成及其生物活性研究

以取代苯甲醛、取代吡啶和取代苯甲酸酯等为原料合成了 10种含硫杂环化合物 (其中 2a～ 2g化合物为国内外未见报道 ) .在合成过程中采用了超声波技术 ,极大地缩短了反应时间 ,提高了收率 .所得化合物的结构经IR ,1 HNMR ,MS和元素分析证实 .对其生物活性进行了初步测试 ,结果证明一些化合物具有良好的抑菌或杀菌作用 ,其中 2b ,2c ,2e ,2h ,2i和2j对大肠杆菌 ( 10 40 7号 )的抗菌效果与CET和SMZ相当 ;2b ,2c ,2f对草绿色链球菌 ( 112 3号 )的抗菌效果与CET和SMZ相当 .     

Preparation and properties of polymer and quantum dot composites

Quantum dots (QDs) were prepared in an organic system through a simple and low-cost wet chemistry method. Polymer beads with a diameter of 60–70 nm and specific functional groups were synthesized by a particular seeded emulsion polymerization technique. QDs were embedded in the polymer beads with the specific functional groups through dissolving and swelling method, which provided the condition for the conjunction of biomolecules and QDs as fluorescent probes. The prepared composites were characterized with UV-Vis, PL, TEM, FTIR, CLSM and conductance titration etc. The results show that QDs are successfully embedded in polymer beads, which breaks the limitation that the conjunction of biomolecules and QDs can be achieved only for those synthesized in aqueous system. __________ Translated from Journal of Shanghai Jiaotong University, 2005, 39(1) (in Chinese)     

Structural Characterization of Anhydroicaritin Glycosides Using ESI—FT—ICR Mass Spectrometry

Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) was used to determine the structures of anhydroicaritin glycosides by the MS/MS experiments of anhydroicaritin glycosides and their methylated derivatives,With high accuracy FT-ICR-MS provides much information about the structures of compounds ,FT-ICR-MS shows the great potential application in the structural characterization of unknown compounds.     

Solid-supported synthesis of a peptide beta-turn mimetic

[structure: see text]The solid-supported synthesis of a bicyclic diketopiperazine, a potential peptide beta-turn mimetic, is described. The Ugi reaction between the resin ester of alpha-N-Boc-diaminopropionic acid (an amine input), alpha-bromo acid, aldehyde, and isocyanide is the key step in the proposed protocol.     

血清中葡萄糖含量CCQM-K11.1国际比对

研究利用同位素稀释质谱法测定血清中的葡萄糖含量，并利用该方法参加国际物质量咨询委员会（CCQM）2005年组织的关键比对CCQM—K11．1，我国国家标准物质研究中心（NRCCRM）的测定结果与韩国（KRISS）和墨西哥（CENAM）的测定结果非常接近，日本（NMIJ）的测定结果离群偏高。     

（＋）－樟脑硫亚胺的合成

合成了四种含樟脑巯基手性助剂的光学活性的硫亚胺化合物。