Synthesis, structure, and action of some gossypol derivatives on the peroxidation of the lipids of biosubstrates

The synthesis has been effected of new gossypol derivatives using piperidino-and morpholinoethylamines. According to their PMR spectra, these substances exist in the keto-amine form. Their action on the peroxidation of lipids (POL) of various biosubstrates has been studied. Gossypol bis(piperinoethylimine) and bis(morpholinoethylimine) in concentrations of 1·10^–7–5·10^–6 mM exert a pronounced antioxidant action on human blood serum and rat brain synaptosomes. In the same concentrations, these substances suppressed the POL in enzymatic and nonenzymatic systems of the oxidation of rat liver microsomes.A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Hematology and Blood Transfusion, Ministry of Health of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 707–712, September–October, 1989.     

Carbohydrates of cultivated varieties ofAlthea rosea

The polysaccharides of three cultivated varieties ofAlthea rosea have been investigated. The amounts of water-soluble polysaccharides and pectin substances in various organs of the plant have been determined. It has been shown that the maximum amount of water-soluble polysaccharides and pectin substances is present in the flowers. Their monosaccharide compositions have been studied. The physicochemical characteristics of the pectin substances are given.     

Extended molecular connectivity: Prediction of boiling points of alkanes

It is shown that extended molecular connectivity may be used for “structure-property” studies. The statistical parameters of the correlation relations of boiling points with extended molecular connectivity indices found for a sample of alkanes (n = 74) are the following: the best two-parameter correlation r = 0.9948, s = 4.7; the best three-parameter correlation r = 0.9971, s = 3.5. Translated fromZhurnal Strukturnoi Khimii, Vol. 38, No. 6, pp. 1154–1159, November–December, 1997.     

The fatty acid composition of the phospholipids of cottonseed oil

Summary 1. The phospholipids of cottonseed oil contain ten fatty acids.2. The positions of the double bonds in the aliphatic chain in the newly discovered unsaturated fatty acids — palmitlinoleic, palmitlinolenic, linolenic, and eicosadienic — have been established by the method of gas-liquid chromatography: they are present at the 6, 9; 6, 9, 12; 9, 12, 15; and 11, 14 carbon atoms, respectively, counting from the carboxyl end of the chain. A saturated fatty acid (myristic) has been found in the phospholipids of cottonseed oil for the first time.Khimiya Prirodnykh Soedinenii, Vol. 1, No. 3, pp. 199–201, 1965     

Polysaccharides ofEremurus. X. Characteristics of the polysaccharides ofEremurus lactiflorus andE. luteus

Water-soluble polysaccharides have been isolated from two species ofEremurus — E. lactiflorus andE. luteus — with yields of 13.5% and 20.5%, respectively. They contained mainly glucose and mannose in ratios of 1:5 and 1:3.1. The polysaccharides ofE. lactiflorus were separated from a column of DEAE-cellulose. The yield of neutral fraction was 10.3%. Gel filtration of the polysaccharides on Sephadex G-200 showed their polydispersity. Homogeneous fractions were obtained by fractional precipitation with ethanol. They have been characterized with respect to monosaccharide composition, molecular weight, and IR spectra.     

Vegetable tanning substances. Dependence of the tanning properties of extracts on their composition

Information is given on vegetable tanning substances, their classification, distribution in the plant world, and structure, and the dependence of their tanning properties on their composition, and also on methods of enriching tanning extracts. The review of literature sources includes publications from 1950 to 1989.A. S. Sadykov Institute of Bioorganic Chemistry, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 293–307, May–June, 1990.     

Condensation of Aniline and o-Hydroxyaniline with 1,2-Dibromoethane

Russian Journal of Organic Chemistry -     

Molecular and crystal structures of hemigossypolone and gossypolone

The results are given of an x-ray structural investigation of hemigossypolone isolated from the stems of a wiltinfected cotton plant and of gossypolone obtained by oxidizing gossypol.     

Synthesis and Interferon-Inducing Activity of Azo-Derivatives of Gossypol and Its Imines

New azo-derivatives of gossypol and its imines were described. Their physicochemical properties and data on their interferon-inducing activity were presented.