Neue Wege zu Polysilanen

Summary Disilane derivatives undergo disproportionation reactions to polysilanes. Investigated were 1,2-dimethyldisilane and 1,2-dimethyltetrachlorodisilane with catalysts like NH₄Cl, AgCN, and Nacyanamide. In case of 1,2-dimethyldisilane, with more than catalytic amounts of NH₄Cl, a nitrogen containing polysilane is formed. Two new compoundsMeSiH(NCO)₂ andMe ₂Si₂(NCO)₄ were synthesized and characterized. The last one leads to a polymer at heating. Additionally an electrochemical formation of polydimethylsilane is described.

     

Error linear complexity measures for multisequences

Complexity measures for sequences over finite fields, such as the linear complexity and the k-error linear complexity, play an important role in cryptology. Recent developments in stream ciphers point towards an interest in word-based stream ciphers, which require the study of the complexity of multisequences. We introduce various options for error linear complexity measures for multisequences. For finite multisequences as well as for periodic multisequences with prime period, we present formulas for the number of multisequences with given error linear complexity for several cases, and we present lower bounds for the expected error linear complexity.     

Some Notes on the Linear Complexity of Sidel’nikov-Lempel-Cohn-Eastman Sequences

We continue the study of the linear complexity of binary sequences, independently introduced by Sidel’nikov and Lempel, Cohn, and Eastman. These investigations were originated by Helleseth and Yang and extended by Kyureghyan and Pott. We determine the exact linear complexity of several families of these sequences using well-known results on cyclotomic numbers. Moreover, we prove a general lower bound on the linear complexity profile for all of these sequences.     

The stresses in single lap joints with a functionally graded adhesive bondline: an efficient modelling approach

In this work, an efficient analytical model for the stress analysis of single lap joints with a functionally graded adhesive bondline is proposed which considers peel as well as shear stresses in the adhesive. The model takes into account the nonlinear geometric characteristics of a single lap joint under tensile loading and allows for the analysis of various adhesive Young's modulus variations. The obtained stress distributions are compared to results of detailed Finite Element analyses and show a good agreement for several single lap joint configurations. In addition, different adhesive Young's modulus distributions and their effect on the peel and shear stresses are studied and discussed in detail. (© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim)     

Recent developments in protein–ligand affinity mass spectrometry

This review provides an overview of direct and indirect technologies to screen protein–ligand interactions with mass spectrometry. These technologies have as a key feature the selection or affinity purification of ligands in mixtures prior to detection. Specific fields of interest for these technologies are metabolic profiling of bioactive metabolites, natural extract screening, and the screening of libraries for bioactives, such as parallel synthesis libraries and small combichem libraries. The review addresses the principles of each of the methods discussed, with a focus on developments in recent years, and the applicability of the methods to lead generation and development in drug discovery.     

A printed nanolitre-scale bacterial sensor array

The last decade has witnessed a significant increase in interest in whole-cell biosensors for diverse applications, as well as a rapid and continuous expansion of array technologies. The combination of these two disciplines has yielded the notion of whole-cell array biosensors. We present a potential manifestation of this idea by describing the printing of a whole-cell bacterial bioreporters array. Exploiting natural bacterial tendency to adhere to positively charged abiotic surfaces, we describe immobilization and patterning of bacterial "spots" in the nanolitre volume range by a non-contact robotic printer. We show that the printed Escherichia coli-based sensor bacteria are immobilized on the surface, and retain their viability and biosensing activity for at least 2 months when kept at 4 °C. Immobilization efficiency was improved by manipulating the bacterial genetics (overproducing curli protein), the growth and the printing media (osmotic stress and osmoprotectants) and by a chemical modification of the inanimate surface (self-assembled layers of 3-aminopropyl-triethoxysilane). We suggest that the methodology presented herein may be applicable to the manufacturing of whole-cell sensor arrays for diverse high throughput applications.