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排序方式: 共有931条查询结果,搜索用时 31 毫秒
901.
Angeli M Bandini M Garelli A Piccinelli F Tommasi S Umani-Ronchi A 《Organic & biomolecular chemistry》2006,4(17):3291-3296
A practical catalytic approach to the synthesis of 4-substituted 1,2,3,4-tetrahydro-beta-carbolines (THBCs, 1) and 1,2,3,9-tetrahydropyrano[3,4-b]indoles (2) via InBr3-catalyzed intramolecular Friedel-Crafts (F-C) cyclization is described. The use of cross-metathesis reaction represents a direct route to the cyclization precursors and the use of InBr3 (5 mol%) allowed polycyclic indole compounds to be isolated in high yields under mild reaction conditions (rt, DCM, minutes). Finally, efforts toward the development of a stereocontrolled version of the present cyclization are presented, highlighting [salenAlCl] and bimetallic [(salenAlCl)2-InBr3] system as promising chiral Lewis acids (ee up to 60%). 相似文献
902.
Silica-coated silver nanowires can be chemically treated to produce a "peapod" architecture in which silver peas are embedded in silica pods. The silver "pea" dimension and interparticle spacings are controllable down to approximately 50 nm. This architecture is potentially useful for chemical sensing, plasmonic, or catalytic applications. 相似文献
903.
De Angelis F Fantacci S Sgamellotti A Cariati E Ugo R Ford PC 《Inorganic chemistry》2006,45(26):10576-10584
We present a combined density functional theory (DFT)/time-dependent density functional theory (TDDFT) study of the geometry, electronic structure, and absorption and emission properties of the tetranuclear "cubane" Cu4I4py4 (py = pyridine) system. The geometry of the singlet ground state and of the two lowest triplet states of the title complex were optimized, followed by TDDFT excited-state calculations. This procedure allowed us to characterize the nature of the excited states involved in the absorption spectrum and those responsible for the dual emission bands observed for this complex. In agreement with earlier experimental proposals, we find that while in absorption the halide-to-pyridine charge-transfer excited state (XLCT*) has a lower energy than the cluster-centered excited state (CC*), a strong geometrical relaxation on the triplet cluster-centered state surface leads to a reverse order of the excited states in emission. 相似文献
904.
Synthesis, characterization, and DFT-TDDFT computational study of a ruthenium complex containing a functionalized tetradentate ligand 总被引:2,自引:0,他引:2
Barolo C Nazeeruddin MK Fantacci S Di Censo D Comte P Liska P Viscardi G Quagliotto P De Angelis F Ito S Grätzel M 《Inorganic chemistry》2006,45(12):4642-4653
A ruthenium complex trans-[Ru(L)(NCS)2], L = 4,4' '-di-tert-butyl-4',4' '-bis(carboxylic acid)-2,2':6',2' ':6' ',2' '-quaterpyridine (N886), was synthesized and characterized by spectroscopic and electrochemical methods. The absorption spectrum of the N886 complex shows metal-to-ligand charge-transfer transitions in the entire visible region and quasi-reversible oxidation and reduction potentials at E(1/2) = +0.38 and -1.92 V vs ferrocene, respectively. The electronic spectra of the N886 complex were calculated by density functional theory (DFT)-time-dependent DFT, which qualitatively reproduces the experimental absorption spectra for both the protonated and deprotonated species. From the analysis of the computed optical transitions of N886, we assign its absorption bands as mixed Ru/SCN-to-quaterpyridine charge-transfer transitions, which extend from the near-IR to the UV regions. The panchromatic response of the N886 complex renders it as a suitable sensitizer for solar energy conversion applications based on titanium dioxide mesoporous electrodes. The preliminary results using the N886 complex as a sensitizer in a dye-sensitized solar cell, with an electrolyte containing 0.60 M butylmethylimidazolium iodide, 0.03 M I2, and 0.50 M tert-butylpyridine in a mixture of acetonitrile and valeronitrile (volume ratio 1:1), show 40% incident photon-to-current efficiencies, yielding under standard AM 1.5 sunlight a short-circuit photocurrent density of 11.8 +/- 0.2 mA/cm(2), an open-circuit voltage of 680 +/- 30 mV, and a fill factor of 0.73 +/- 0.03, corresponding to an overall conversion efficiency of 5.85%. 相似文献
905.
Masciocchi N Galli S Sironi A Cariati E Galindo MA Barea E Romero MA Salas JM Navarro JA Santoyo-Gonzalez F 《Inorganic chemistry》2006,45(19):7612-7620
Thermally robust materials of the M(5-X-pyrimidin-2-olate)2 type [M = Co, X = Cl (1(Cl)), X = Br (1(Br)), X = I (1(I)); M = Zn, X = Cl (2(Cl)), X = Br (2(Br)), X = I (2(I))] have been synthesized. Their X-ray powder diffraction structural characterization has revealed that they crystallize as I2d diamondoid frameworks, isomorphous to those of the pristine [M(pyrimidin-2-olate)2]n analogues (1(H), M = Co; 2(H), M = Zn). The magnetic measurements of the 1(X) series at magnetic fields of 100, 300, and 5000 Oe reveal a weak ferromagnetic ordering taking place below the Néel temperature (T(N) approximately 20 K), arising from spin canting phenomena of the antiferromagnetically coupled cobalt centers. Moreover, magnetic hysteresis studies carried out on the 1(X) series at 2 K reveal a strong dependence of both the coercive field H(coer) (2500, 1000, 775, and 500 Oe for 1(Br), 1(Cl), 1(I), and 1(H), respectively) and the remnant magnetization M(rem) (0.0501 mu(B) for 1(Br) and 1(Cl), 0.0457 mu(B) for 1(I), and 0.0358 mu(B) for 1(H)) on the 5-substituent of the pyrimidin-2-olates. The molecular alloys [Co(5-Y-pyrimidin-2-olate)2] (Y = Cl/Br, 1(Cl/Br)) and [Co(5-Y'-pyrimidin-2-olate)2] (Y' = Br/I, 1(Br/I)) have also been prepared and characterized, proving that they have intermediate properties. These materials combine interesting functional properties, such as chemical inertness, magnetism, photoluminescence, and (although weak) SHG activity. 相似文献
906.
Albano VG Bandini M Barbarella G Melucci M Monari M Piccinelli F Tommasi S Umani-Ronchi A 《Chemistry (Weinheim an der Bergstrasse, Germany)》2006,12(3):667-675
The synthesis, characterization, and structure-guided application of a new class of highly versatile chiral C(2)-symmetric diamine-oligothiophene ligands in Pd-catalyzed asymmetric transformations are presented. Experimental investigations of the intimate role of pendant pi-conjugate oligothiophenes in determining the catalytic activity of the corresponding chiral Pd complexes are described. Their unusual behavior opens up new routes toward the logical design of finely tuned organometallic catalysts by remote structural functionalizations. 相似文献
907.
Alterio V Vitale RM Monti SM Pedone C Scozzafava A Cecchi A De Simone G Supuran CT 《Journal of the American Chemical Society》2006,128(25):8329-8335
The X-ray crystal structure of the fluorescent antitumor sulfonamide carbonic anhydrase (CA, EC, 4.2.1.1) inhibitor (4-sulfamoylphenylethyl)thioureido fluorescein (1) in complex with the cytosolic isoform hCA II is reported, together with a modeling study of the adduct of 1 with the tumor-associated isoform hCA IX. Its binding to hCA II is similar to that of other benzesulfonamides, with the ionized sulfonamide coordinated to the Zn2+ ion within the enzyme active site, and also participating in a network of hydrogen bonds with residues Thr199 and Glu106. The scaffold of 1 did not establish polar interactions within the enzyme active site but made hydrophobic contacts (<4.5 A) with Gln92, Val121, Phe131, Val135, Leu198, Thr199, Thr200, and Pro202. The substituted 3-carboxy-amino-phenyl functionality was at van der Waals distance from Phe131, Gly132, and Val135. The bulky tricyclic fluorescein moiety was located at the rim of the active site, on the protein surface, and strongly interacted with the alpha-helix formed by residues Asp130-Val135. All these interactions were preserved in the hCA IX-1 adduct, but the carbonyl moiety of the fluorescein tail of 1 participates in a strong hydrogen bond with the guanidine moiety of Arg130, an amino acid characteristic of the hCA IX active site. This may account for the roughly 2 times higher affinity of 1 for hCA IX over hCA II and may explain why in vivo the compound specifically accumulates only in hypoxic tumors overexpressing CA IX and not in the normal tissues. The compound is in clinical studies as an imaging tool for acute hypoxic tumors. 相似文献
908.
Bandini M Melloni A Piccinelli F Sinisi R Tommasi S Umani-Ronchi A 《Journal of the American Chemical Society》2006,128(5):1424-1425
A novel Pd-catalyzed intramolecular allylic alkylation of indoles allows THBCs and THGCs to be effectively synthesized in high yields and excellent enantiomeric excesses (ee up to 97%). 相似文献
909.
Maria-Beatrice Coltelli Simona Bronco Carlos Chinea 《Polymer Degradation and Stability》2010,95(3):332-341
The blending of PLA with poly(butylene-adipate-co-terephthalate) (PBAT) is a promising strategy to achieve a toughened multiphase material. The blends ductility could be further improved through reactive compatibilization, i.e. inducing the formation of comb PLA-PBAT copolymers during the melt blending. In the present work a non-selective strategy was adopted which consisted in the use of a peroxide, 2,5-Dimethyl-2,5-di(tert-butylperoxy)hexane. The phase morphology development and the final properties (torque, fluidity in the melt, tensile behaviour, thermal and dynamical-mechanical features) of the blends were studied as a function of the peroxide concentration. The elongation at break was improved up to a maximum value thanks to this approach and a corresponding minimum was observed in the value of the dispersed phase diameter. A structural characterization of the macromolecules formed during the reactive process was attempted by using size exclusion chromatography of the blends and comparison with the pure polymers obtained by processing in the presence of the peroxide. 相似文献
910.
Valeria Cavatorta Stefano Sforza Guido Mastrobuoni Giuseppe Pieraccini Simona Francese Gloriano Moneti Arnaldo Dossena Elide Anna Pastorello Rosangela Marchelli 《Journal of mass spectrometry : JMS》2009,44(6):891-897
The lipid transfer protein (LTP), Pru p 3, has been identified as the major allergen present in peach, and its sequence obtained by direct amino acid sequencing has been previously reported. However, several sequences, obtained from c‐DNA and available in databases, show differences among them and from the originally proposed structure. In this paper, we report the fast and unambiguous determination of the structure of Pru p 3 protein, extracted from three different varieties of peach, by electrospray ionization mass spectrometry (ESI‐MS), both coupled to single stage (quadrupole) or advanced (FT‐HRMS) analyzers. The structure was identical to one of the cDNA‐derived sequences and different in two positions from the previously reported structure obtained by amino acid sequencing. Moreover, the exclusive localization of the protein in the outer part of the fruits was assessed by Matrix‐Assisted Laser Desorption Ionization Mass Spectrometry Imaging (MALDI MSI). The results reported here demonstrate the full potential of mass spectrometry for rapidly obtaining high quality structural data of relevant food proteins. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献