Synthesis,characterization and coordination chemistry of substituted β-amino dicarbonyls

An efficient and facile method for the synthesis of novel structurally diverse β-amino dicarbonyl compounds is described by exploring the aza-Michael addition reaction in an aqueous medium as a key step. Thereby, 2-(aryl-disubstituted-amino-1-yl-methyl)-malonic acid diethyl esters were achieved in a good to excellent yields. These products were easily isolated with enough purity just by using simple recrystallization. The crystals of the compounds (17) and (24) have been obtained and studied by X-ray crystallographic analyses.     

The Multifunctional Role of Herbal Products in the Management of Diabetes and Obesity: A Comprehensive Review

Obesity and diabetes are the most demanding health problems today, and their prevalence, as well as comorbidities, is on the rise all over the world. As time goes on, both are becoming big issues that have a big impact on people’s lives. Diabetes is a metabolic and endocrine illness set apart by hyperglycemia and glucose narrow-mindedness because of insulin opposition. Heftiness is a typical, complex, and developing overall wellbeing worry that has for quite some time been connected to significant medical issues in individuals, all things considered. Because of the wide variety and low adverse effects, herbal products are an important hotspot for drug development. Synthetic compounds are not structurally diverse and lack drug-likeness properties. Thus, it is basic to keep on exploring herbal products as possible wellsprings of novel drugs. We conducted this review of the literature by searching Scopus, Science Direct, Elsevier, PubMed, and Web of Science databases. From 1990 until October 2021, research reports, review articles, and original research articles in English are presented. It provides top to bottom data and an examination of plant-inferred compounds that might be utilized against heftiness or potentially hostile to diabetes treatments. Our expanded comprehension of the systems of activity of phytogenic compounds, as an extra examination, could prompt the advancement of remedial methodologies for metabolic diseases. In clinical trials, a huge number of these food kinds or restorative plants, as well as their bioactive compounds, have been shown to be beneficial in the treatment of obesity.     

Novel Zwitterionic Sulfides,Selenides and Tellurides

The zwitterionic compounds Im‐E‐Mel [ 9 , E = S ( a ), Se ( b ), Te ( c ), Im = 2‐{1, 3‐diisopropyl‐4, 5‐dimethylimidazolium}, Mel = 5‐{2, 2‐dimethyl‐4, 6‐dioxo‐1, 3‐dioxan‐5‐ylide}] are obtained from the corresponding 2‐chalcogeno‐1, 3‐diisopropyl‐4, 5‐dimethylimidazolines 8 and 5‐bromo‐2, 2‐dimethyl‐4, 6‐dioxo‐1, 3‐dioxan ( 7 ) in the presence of triethylamine in excellent yields. The crystal structures of the thermally stable compounds reveal most effective charge separations from which the compounds 9 resemble closely to diaryl chalkogenides. 9b and 9c are the first selenocarbonyl and tellurocarbonyl ylides reported, to our knowledge.     

Hydrothermal synthesis of magnetic Fe<Subscript>3</Subscript>O<Subscript>4</Subscript>–nitrogen-doped graphene hybrid composite and its application as photocatalyst in degradation of methyl orange and methylene blue dyes in presence of copper (II) ions

Nanocomposite of Fe₃O₄–nitrogen-doped graphene (Fe₃O₄–NG) was synthesized by single step hydrothermal method. The as-synthesized composite was characterised by various techniques such as powder X-ray diffraction, Fourier-transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, vibrating sample magnetometry and thermal analysis (TGA). The catalytic role of synthesized nanocomposite in visible light induced photodegradation of methyl orange (MO; acidic dye) and methylene blue (MB; basic dye) was explored. The role of Cu(II) ions on the photodegradation of the organic dyes was also monitored. Cu(II) ions enhance the photocatalytic activity of nanocomposite by capturing photoelectron, thereby quenching the recombination process of electron–hole pair in photocatalyst.     

A case of chain propagation: α-aminoalkyl radicals as initiators for aryl radical chemistry

The generation of aryl radicals from the corresponding halides by redox chemistry is generally considered a difficult task due to their highly negative reduction potentials. Here we demonstrate that α-aminoalkyl radicals can be used as both initiators and chain-carriers for the radical coupling of aryl halides with pyrrole derivatives, a transformation often employed to evaluate new highly reducing photocatalysts. This mode of reactivity obviates for the use of strong reducing species and was also competent in the formation of sp² C–P bonds. Mechanistic studies have delineated some of the key features operating that trigger aryl radical generation and also propagate the chain process.

Aminoalkyl radicals can be used as both initiators and chain-carriers for the conversion of aryl halides into the corresponding radicals. This approach by-passes the requirement for strongly reducing photocatalysts.     

Wasserstoffbrückenbindungen mit Cyanidionen? Die Strukturen von 1,3‐Diisopropyl‐4,5‐dimethylimidazoliumcyanid und 1‐Isopropyl‐3,4,5‐trimethylimidazoliumcyanid

Hydrogen Bonds with Cyanide Ions? The Structures of 1,3‐Diisopropyl‐4,5‐dimethylimidazolium Cyanide and 1‐Isopropyl‐3,4,5‐trimethylimidazolium Cyanide 1,3‐Diisopropyl‐4,5‐dimethylimidazolium cyanide ( 2a ) and 1‐isopropyl‐3,4,5‐trimethylimidazolium cyanide ( 2b ) are obtained from the reaction of the corresponding 2,3‐dihydrodimethylimidazol‐2‐ylidenes ( 1 ) and hydrogen cyanide in excellent yield. Their crystal structure analyses reveal the presence of ion pairs linked by hydrogen bonds. The crystal structure analysis of 2a reveals a near colinear orientation of the C(1)‐H bond axis and the cyanide ion while in 2b this orientation is perpendicular. In both cases, the interionic distances are in the expected range for hydrogen bonds. Ab‐initio calculations of the total energy of the salts 2 indicate small differences in energy between the colinear and perpendicular orientation of the ions as well as between the colinear C‐H···C‐N and C‐H···N‐C orientations. The comparison of calculated and measured ¹³C and ¹⁵N NMR chemical shifts does not allow the distinction between the possible orientations.     

Terpenoids—LXXII: Chemical studies of marine invertebrates—XXVI Δ9(12)-capnellene-3β,8β,10α,14-tetrol,a novel polyoxygenated sesquiterpene from the alcyonarian capnella imbricata

The structure determination of the new sesquiterpene, Δ9(12)-capnellene- 3β,8β,10α,14-tetrol 1, is described.     

Mechanism of formation of applicable linear boron-nitrogen polymers

This paper contains a literature review on the mechanism of formation of applicable linear boron-nitrogen polymers.

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Zusammenfassung Dieser Artikel enthält eine Literaturübersicht über den Bildungsmechanimus anwendbarer Bor-Stickstoffpolymerer.

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Résumé Cet article contient une revue des publications sur le mécanisme de formation des polymères de bore-azote.

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Standardization of Biomarkers Gallic Acid and Berberine in Polyherbal Formulation Entoban Capsules by High-Performance Thin-Layer Chromatography—Densitometry

JPC – Journal of Planar Chromatography – Modern TLC - The technological improvement in the structural elucidation of natural compounds has made it probable to generate appropriate...