Study of the energy and charged multiplicity dependence of inclusiveπ− production in π−p interactions up to fermilab energies

Using new data from 100 $\text{GeV}\text{c π}{}^{\mathrm{?}}$ interactions, we find the energy dependence of the invariant cross-section in the target fragmentation (central) region to be consistent with an $\text{A + Bs}{}^{\mathrm{<mtext>?</mtext><mtext>1</mtext><mtext>2</mtext>}}\text{(C + Ds}{}^{\mathrm{<mtext>?</mtext><mtext>1</mtext><mtext>4</mtext>}}\text{)}$ behavior. The leading particle peak near x = + 1 exhibits a width in x which becomes smaller with increasing energy and an integrated cross section which is approximately energy independent.     

Synthesis of silylene and silyl(silylene)metal complexes

In 1987, two research groups published the first-ever reports on the synthesis of silylene complexes and presented structural evidence. Since then, a range of synthetic methods have been developed and a number of silylene complexes have been prepared. In 1988, we reported on the first base-stabilized bis(silylene) complexes that can be regarded as being masked silyl(silylene) complexes. These complexes occupy a unique position among silylene and silyl(silylene) complexes in that they provide a convenient tool for studying the reactivity of coordinated silylenes. They are stable enough to be isolated, but the bond between the silylene silicon atom and the internal base can easily be cleaved by thermal perturbation to generate real silyl(silylene) complexes. To date, a number of base-stabilized bis(silylene) complexes have been prepared in which the central metals range from group 5 to group 9. Only two base-free silyl(silylene) complexes have been prepared. One is prepared by reacting a platinum complex with a stable silylene; the other is produced by the photolysis of a tungsten complex in the presence of a hydrodisilane.     

Adsorption of phenol in flow systems by a monolithic carbon cryogel with a microhoneycomb structure

Adsorption of phenol from an aqueous solution in batch and continuous flow systems using carbon gels with a microhoneycomb structure (carbon gel microhoneycombs, CMHs) was studied. The obtained monolithic CMHs had fairly straight channels, 25–45 μm in diameter, and the thickness of the walls which form the channels was around 5 μm. The CMHs showed 370 times lower hydraulic resistance when compared with a column packed with particles having the same diffusion path length as it. The obtained CMHs have a hierarchical micro-meso porous structure giving BET surface area in the range of 513–1070 m²·g^?1.When used for phenol adsorption from an aqueous solution, the CMHs quickly adsorbed phenol at first, and then, the uptake gradually increased, which indicates that the adsorption mechanism is based on not only simple physisorption. The phenol adsorption capacity increased with the increase in carbonization temperature of the CMH and the decrease in its hydrophilicity. CMHs carbonized at temperatures higher than 1073 K showed the highest phenol adsorption capacity which was around 160 mg·g^?1. The CMHs could continuously adsorb phenol from aqueous solutions, and their length of unused bed (LUB) values depended on operation conditions but were in the range of 0.3–0.7 cm. The experimental results indicated that carbon cryogels with a microhoneycomb structure have a high potential to be used for effective separation of phenol.     

Fluid flow in a rotating cylindrical container with a rotating disk at the fluid surface

Fluid flow in a rotating cylindrical container of radius R_w and height H with a co-axially rotating disk of radius R_d at the fluid surface is numerically investigated. The container and the disk rotate with angular velocities Ω_w and Ω_d, respectively. We solve the axisymmetric Navier-Stokes equations using a finite-volume method. The effects of the relative directions and magnitudes of the disk and container rotations are studied. The calculations are carried out with various ratios of Ω_w and Ω_d for H/R_w = 2 and R_d/R_w = 0.7. Streamlines and velocity vectors in the meridional plane and azimuthal velocities are obtained. The flow fields in the meridional plane are discussed with relation to azimuthal velocities in the interior of the container. The numerical results are also compared with experimental data.     

Discovery of a novel acyl-CoA: cholesterol acyltransferase inhibitor: the synthesis, biological evaluation, and reduced adrenal toxicity of (4-phenylcoumarin)acetanilide derivatives with a carboxylic acid moiety

As a part of our research for novel potent and orally available acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors that can be used as anti-atherosclerotic agents, we recently reported the discovery of the (4-phenylcoumarine)acetanilide derivative 1. However, compound 1 showed adrenal toxicity in animal models. In order to search for safer ACAT inhibitors that do not have adrenal toxicity, we examined the inhibitory activity of ACAT in human macrophage and adrenal cells. The introduction of a carboxylic acid moiety on the pendant phenyl ring and the adjustment of the lipophilicity led to the discovery of (2E)-3-[7-chloro-3-[2-[[4-fluoro-2-(trifluoromethyl)phenyl]amino]-2-oxoethyl]-6-methyl-2-oxo-2H-chromen-4-yl]phenyl]acrylic acid (21e), which showed potent ACAT inhibitory activity in macrophages and a selectivity of around 30-fold over adrenal cells. In addition, compound 21e showed high adrenal safety in guinea pigs.     

Growth and luminescent properties of Yb—doped oxide single crystals for scintillator application

Rod-shaped (Lu_1−xYb_x)₃Al₅O₁₂ with x=0.05, 0.15, 0.30 and (Y_1−xYb_x)AlO₃ with x=0.05, 0.10, 0.30 single crystals were grown by the micro-pulling-down method. Edge-defined film-fed growth method was used to prepare (Y_0.9Yb_0.1)VO₄ crystal, while Ca₈(La_1.98Yb_0.02)(PO₄)₆O₂ crystal was grown by the Czochralski method. Luminescence of these crystals was studied with main attention paid to the charge transfer emission of Yb³⁺. Temperature tuned decay times in the time scale of units—tens of nanosecond was measured as a feature possibly interesting for an application in scintillation detectors in positron emission tomography.