Liquid Phase Acylation of Alcohols with Acetic Acid Over Zeolites

The liquid phase acylation of primary and secondary alcohols were carried out with acetic acid in the presence of zeolites. LaY zeolite is found to be the best catalyst.     

H2SO4-Promoted Synthesis of (E)-Stilbenes from Substituted Phenylacetones and Substituted Benzaldehydes Through Tandem Aldol–Grob Reaction

Stilbene derivates (stilbenoids) are present in plants and show a wide range of biological activities and potential therapeutic value. In continuation of our natural product synthesis program, an efficient, simple, and practical method has been developed to regioselectively synthesize (E)-stilbenes using H₂SO₄ as a catalyst in a short time (30–60 s) at room temperature in good to excellent yields.

Multicomponent synthesis and anticancer activity studies of novel 6-(Trifluoromethyl)-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylate derivatives

A series of novel 6-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate derivatives were obtained in good yields from ethyl 4,4,4-trifluoro-3-oxobutanoate, urea, and aryl aldehyde via Biginelli multicomponent reaction. All the corresponding products 4a–4p were examined against four human cancer cell lines (A549, HepG2, COLO205 and DU145) and compounds 4e, 4i, and 4?m which showed promising anticancer activity have been identified.     

A Hybrid Symbiosis Organisms Search algorithm and its application to real world problems

In this paper, a new hybrid algorithm, Hybrid Symbiosis Organisms Search (HSOS) has been proposed by combining Symbiosis Organisms Search (SOS) algorithm with Simple Quadratic Interpolation (SQI). The proposed algorithm provides more efficient behavior when dealing with real-world and large scale problems. To verify the performance of this suggested algorithm, 13 (Thirteen) well known benchmark functions, CEC2005 and CEC2010 special session on real-parameter optimization are being considered. The results obtained by the proposed method are compared with other state-of-the-art algorithms and it was observed that the suggested approach provides an effective and efficient solution in regards to the quality of the final result as well as the convergence rate. Moreover, the effect of the common controlling parameters of the algorithm, viz. population size, number of fitness evaluations (number of generations) of the algorithm are also being investigated by considering different population sizes and the number of fitness evaluations (number of generations). Finally, the method endorsed in this paper has been applied to two real life problems and it was inferred that the output of the proposed algorithm is satisfactory.     

Preparation,spectral characterization,in vitro antitumor and thermal studies of new platinum(IV) and palladium(II) thiohydrazone complexes

Pt^IV and Pd^II complexes [Pt(L)₂Cl₂] and [Pd(HL)Cl₂] [HL = salicyclaldehyde morpholine N-thiohydrazone (HL¹), benzaldehyde morpholine N-thiohydrazone (HL²), acetophenone morpholine N-thiohydrazone (HL³), p-methylacetophenone morpholine N-thiohydrazone (HL⁴), cinnamaldehyde morpholine N-thiohydrazone (HL⁵), cyclohexanone morpholine N-thiohydrazone (HL⁶), benzaldehyde aniline N-thiohydrazone (HL⁷), benzaldehyde N-(methyl, cyclohexyl)-thiohydrazone (HL⁸) and benzaldehyde N-(ethyl, cyclohexyl)-thiohydrazone (HL⁹)] were prepared in MeOH and characterized by elemental analysis, i.r., electronic, ¹H-n.m.r. and ¹³C-n.m.r. spectral data. For some of the complexes cyclic voltammetric and thermal studies were carried out. The in vitro antitumor activity of some complexes was measured.     

Thermal decomposition of zinc and cadmium zirconyl oxalates

The enthalpy of formation at 298.15 K of the polymer Al₁₃O₄(OH)₂₈(H₂O)³⁺₈ and an amorphous aluminium trihydroxide gel was studied using an original differential calorimetric method, already developed for adsorption experiments, and aluminium-27 NMR spectroscopy data. ΔH_f “Al₁₃” (298.15 K) = ? 602 ± 60.2 kJ mole^?1 and ΔH_f Al(OH)₃ (298.15 K) = ? 51 ± 5 kJ mole^?1. Using theoretical values of ΔG_R “Al₁₃” and ΔG_R Al(OH)₃, we calculated ΔG_f “Al₁₃” (298.15 K) = ? 13282 kJ mole^?1; ΔS_f “Al₁₃” (298.15 K) = + 42.2 kJ mole^?1; ΔG_f Al(OH)₃ (298.15 K) = ? 782.5 kJ mole^?1; and ΔS_f Al(OH)₃ (298.15 K) = + 2.4 kJ mole^?1.     

A facile regioselective ring opening of aziridines to haloamines using tetrabutylammonium halides in the presence of β-cyclodextrin in water

A variety of N-tosylaziridines undergo regioselective ring opening with tetrabutylammonium halides in the presence of β-cyclodextrin in water at pH 4 and room temperature to afford the corresponding haloamines in excellent yields.     

Halide and complex halogeno anions as salts of oxinato bis(η5-indenyl)titanium(IV)/zirconium(IV) chelates

Bis(η⁵-indenyl)titanium(IV) dichloride and bis(η⁵-indenyl)zirconium(IV) dichloride, when treated with 8-hydroxyquinoline (oxine) in aqueous medium form ionic derivatives of the type [(η⁵-C₉H₇)₂ML]⁺Cl^? (M = Ti(IV), Zr(IV), L is the conjugate base of oxine). A number of halide and complex halogeno anions present in aqueous solution were isolated as salts of these ionic complexes giving derivatives of the type, [(η⁵-C₉H₇)₂ML]⁺X^? (X = Br^?, I^?, ZnCl₃(H₂O)^?, CdCl₄^2?, HgCl₃^?). Conductivity measurements in nitrobenzene indicate that these complexes are electrolytes. Both the IR and ¹H NMR spectral studies demonstrate that the ligand L is chelating. Consequently there is tetrahedral coordination about the titanium(IV) or zirconium(IV) ion.     

Effect of disperse dye structure on dye sorption onto PLA fiber

The effect of the structure of various disperse dyes on their percentage sorption onto polylactide (PLA) is explained using molecular modeling. The interaction energies between the dyes and PLA have been calculated, and a linear equation has been developed to predict the percentage sorption on PLA based on the dye-PLA interaction energy. The predicted percentage sorption for a dye is shown to agree with its experimentally obtained percentage sorption on commercial PLA fabric and on PLA fiber extruded in our laboratory. Within the dyes, the functional groups that form the strongest interactions with PLA are -N(C(2)H(4)OCOCH(3))(2), -(CO)(2)NC(3)H(6)OCH(3), -SO(2)NHC(6)H(5), -NO(2), -CN(NH)C(6)H(4), and -CH(CO)(2)C(6)H(4), and the groups that form the weakest interactions with PLA are -Br and -Cl.