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61.
AKHTER Kulsoom AHMED Muhammed Naeem GHOUS Tahseen RASHEED Basharat TAHIR Muhammad Nawaz ARSHAD Ifzan 《结构化学》2019,38(9)
The structure of 1-hydroxy-3,5-dimethoxy-9 H-xanthen-9-one isolated from chloroform extract of Ajuga bracteosa root was analyzed by single-crystal X-ray diffraction. DPPH(1,1-diphenyl-2-picryl hydrazyl), ABTS(2,2?-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activities(RSA) and Fe2+ chelating activities were carried out to determine the antioxidant potential of the compound. RSA values for the compound were 96%, 96% and 96% for all the three activities respectively at maximum concentration of the compound(100 μ gmL-1) with the IC50 values of 3.40, 4.86 and 0.10(μ gmL-1). Antidiabetic activities including antiglycation and α-glucosidase inhibition were also performed where the antiglycation activity was performed using two techniques including spectrofluorometric as well as spectrophotometric technique. Spectrofluorometric technique provided 97% antiglycation potential while 92% antiglycation potential was observed by spectrophotometric technique for the isolated compound. The compound at a concentration of 10 μ gmL-1 exhibited 31% α-glucosidase inhibitory potential with IC50 of 15.56 μ gmL-1. Antimicrobial activity data showed that the compound was active against all the studied pathogenic bacteria. 相似文献
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A. Muhammed Uludağ 《manuscripta mathematica》2001,106(3):271-277
We give a recipe for finding new examples of plane curves with a finite non-abelian fundamental group of the complement and
new examples of Zariski pairs of plane curves.
Received: 18 December 2000 / Revised version: 27 April 2001 相似文献
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Muhammed een Jong Min Oh Zeynep
zdemir Saliha Ebru Büyüktuncel Mehtap Uysal Mohamed A. Abdelgawad Arafa Musa Nicola Gambacorta Orazio Nicolotti Bijo Mathew Hoon Kim 《Molecules (Basel, Switzerland)》2020,25(22)
Twelve pyridazinones (T1–T12) containing the (2-fluorophenyl) piperazine moiety were designed, synthesized, and evaluated for monoamine oxidase (MAO) -A and -B inhibitory activities. T6 was found to be the most potent MAO-B inhibitor with an IC50 value of 0.013 µM, followed by T3 (IC50 = 0.039 µM). Inhibitory potency for MAO-B was more enhanced by meta bromo substitution (T6) than by para bromo substitution (T7). For para substitution, inhibitory potencies for MAO-B were as follows: -Cl (T3) > -N(CH3)2 (T12) > -OCH3 (T9) > Br (T7) > F (T5) > -CH3 (T11) > -H (T1). T6 and T3 efficiently inhibited MAO-A with IC50 values of 1.57 and 4.19 µM and had the highest selectivity indices (SIs) for MAO-B (120.8 and 107.4, respectively). T3 and T6 were found to be reversible and competitive inhibitors of MAO-B with Ki values of 0.014 and 0.0071, respectively. Moreover, T6 was less toxic to healthy fibroblast cells (L929) than T3. Molecular docking simulations with MAO binding sites returned higher docking scores for T6 and T3 with MAO-B than with MAO-A. These results suggest that T3 and T6 are selective, reversible, and competitive inhibitors of MAO-B and should be considered lead candidates for the treatment of neurodegenerative disorders like Alzheimer’s disease. 相似文献
66.
Jais Abdul Azim Ali S. A. Muhammed Anwar Mustafa Somalu Mahendra Rao Muchtar Andanastuti Isahak Wan Nor Roslam Wan Baharudin Nurul Akidah Lim Kean Long Brandon Nigel P. 《Journal of Solid State Electrochemistry》2020,24(3):711-722
Journal of Solid State Electrochemistry - Nickel/scandia-ceria-stabilized-zirconia (Ni/10Sc1CeSZ) cermet is a potential anode for solid oxide fuel cells. The anode powder is prepared through a... 相似文献
67.
T. Gamze Ulusoy Ghobadi Amir Ghobadi Muhammed Buyuktemiz Elif Akhuseyin Yildiz Dilara Berna Yildiz H. Gul Yaglioglu Yavuz Dede Ekmel Ozbay Ferdi Karadas 《Angewandte Chemie (International ed. in English)》2020,59(10):4082-4090
Herein, we establish a simple synthetic strategy affording a heterogeneous, precious metal‐free, dye‐sensitized photoelectrode for water oxidation, which incorporates a Prussian blue (PB) structure for the sensitization of TiO2 and water oxidation catalysis. Our approach involves the use of a Fe(CN)5 bridging group not only as a cyanide precursor for the formation of a PB‐type structure but also as an electron shuttle between an organic chromophore and the catalytic center. The resulting hetero‐functional PB‐modified TiO2 electrode demonstrates a low‐cost and easy‐to‐construct photoanode, which exhibits favorable electron transfers with a remarkable excited state lifetime on the order of nanoseconds and an extended light absorption capacity of up to 500 nm. Our approach paves the way for a new family of precious metal‐free robust dye‐sensitized photoelectrodes for water oxidation, in which a variety of common organic chromophores can be employed in conjunction with CoFe PB structures. 相似文献
68.
Muhammed Talat Sariaydin Talat Krpinar 《Mathematical Methods in the Applied Sciences》2019,42(16):5154-5158
In this paper, we study the Bäcklund transformations for the adjoint curve in the Euclidean 3‐space. Firstly, it is obtained some essential equations of the Bäcklund transformation. After this, we give a new theorem, the Bäcklund transformations for the adjoint curve in Euclidean 3‐space. 相似文献
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