AlCl(3) x 6H(2)O/KI/H(2)O/CH(3)CN: a new alternate system for dehydration of oximes and amides in hydrated media

Dehydration of oximes and amides to nitriles was carried out using the AlCl(3) x 6H(2)O/KI/H(2)O/CH(3)CN system. It produced isoquinoline derivatives 8a-c (Bischler Naperialski reaction) when reacted with amides 7a-c in hydrated media. Also, the keto oximes produced anilides (Beckmann rearrangement) with the system under the same reaction conditions.     

Some contribution to W(VI)-peroxo-chemistry: Synthesis,spectroscopic characterization,reactivity and DFT studies

Synthesis of white microcrystalline oxodiperoxotungstate(VI) complexes, K[WO(O₂)₂(L)(H₂O)]·H₂O, (L ?= ?salicylate, 5-chlorosalicylate, 4-hydroxybenzoate) have been achieved from reaction of Na₂WO₄·2H₂O with 30% H₂O₂ and the respective hetero-ligands at pH Ca. 7–7.5 in aqueous medium. The newly synthesized compounds were comprehensively characterized by elemental analyses, spectral studies, room temperature magnetic moment measurements and mass spectrometric studies. Infrared spectra suggest that, peroxo groups are bonded to the WO⁺⁴ center in a triangular bidentate (C_2v) fashion and the hetero-ligands benzene-core hydroxycarboxylic acids viz. salicylic acid, 5-chlorosalicylic acid, 4-hydroxybenzoic acid in anoinic form are coordinated in monodentate manner. Compounds are fairly stable in aqueous solution for sufficient period of time. The results of mass spectrometric analysis lend support to the molecular composition of the complexes ascertained on the basis of elemental analyses and spectroscopic studies. Compound potassium(aquo)(5-chlorosalicylato)oxodiperoxotungstate(VI)monohydrate, K[WO(O₂)₂(5-chlorosalicylate)(H₂O)]·H₂O, act as an oxidant of bromide ion in aqueous phase bromination of chosen organic substrates to their corresponding bromo organics. Density Functional Theory (TD-DFT) calculations were performed on the synthesized complexes substantiated the experimentally obtained results. The TD-DFT optimized structures are in excellent agreement with the results of elemental analyses, spectral as well as mass spectrometric data.     

Towards meso‐Ester BODIPYs with Aggregation‐Induced Emission Properties: The Effect of Substitution Positions

Three meso‐ester boron dipyrromethene (BODIPY) dyes have been synthesized and functionalized with aggregation‐induced emission (AIE)‐active tetraphenylethene or triphenylethene moieties. It was found that functionalizing at the different positions of the BODIPY core resulted in the final dye having different emission properties in response to aggregation: from aggregation‐induced quenching (ACQ) to being AIE active. X‐ray crystallographic analysis was thus performed to provide an explanation for these differences.     

Intercalation of copper salt to montmorillonite K-10 and its application as a reusable catalyst for Chan–Lam cross-coupling reaction

A simple and efficient catalytic system has been developed by adsorption of copper salt in the interlayers of montmorillonite K-10. The catalytic system impressively exercises the green chemistry perspective leading to effortless recovery and recyclability for the cross-coupling of arylboronic acids and N-nucleophiles. The effect of catalytic activity was studied for electronically diverse arylboronic acids and imidazoles relying on various optimizations under optimum thermal condition. The catalytic system was characterized and the morphology was determined.     

Zinc triflate: a highly efficient reusable catalyst in the synthesis of functionalized quinolines via Friedlander annulation

An environmentally friendly and highly efficient procedure for the preparation of quinolines and fused polycyclic quinolines has been developed by a simple Friedlander annulation reaction of 2-aminoaryl ketone with carbonyl compounds in presence of zinc triflate under microwave irradiation and solvent-free conditions. The reaction also proceeds effectively when In(OTf)₃ was used in lieu of Zn(OTf)₂ as the catalyst. The catalyst can be recovered after the reaction and reused efficiently in subsequent runs.     

A simple,quick and novel protocol for biaryl synthesis using LiCl‐promoted in situ‐generated Pd nanoparticles

This paper describes a simple and a very quick protocol for biaryl synthesis using the Suzuki–Miyaura cross‐coupling reaction. A quintessential role of salting‐out agent LiCl was observed in the Suzuki–Miyaura cross‐coupling reaction that enhanced the reduction rate of Pd (II) to a considerable extent, resulting in the formation of nanosized palladium in a few seconds. The isolated Pd nanoparticles were characterized with X‐ray diffraction, dynamic light scattering, TGA, transmission electron microscopy and scanning electron microscopy‐dispersive X‐ray spectroscopy. The Suzuki–Miyaura cross‐coupling reaction proceeded very well with the in situ‐generated Pd nanocatalysts furnishing the desired biaryl adducts with excellent yields.     

A Facile Transfer of Dicyano Methylene Group Between Arylidenemalononitrile and Aldehyde

Arylidenemalononitrile undergoes facile exchange of dicyano methylene group with β-formyl steroidal enamide as well as aromatic aldehydes under mild base catalysed reaction.     

A New Efficient Commercial Iron Mediated Debromination of Aryl Substituted Vic-Dibromide

Debromination of vic-dibromides with commercially available metallic iron in a methanolic medium affords alkenes and alkynes in excellent yields.     

Microwave-assisted Pd-catalyzed synthesis of fused steroidal and non-steroidal pyrimidines from β-halo-α,β-unsaturated aldehydes

A Pd-catalyzed protocol has been developed for the synthesis of fused steroidal and non-steroidal pyrimidines from β-halo-α,β-unsaturated aldehydes under microwave irradiation. The β-halo-α,β-unsaturated aldehydes are synthesized from corresponding ketones using Vilsmeier formylation reaction. This synthetic protocol is utilized to synthesize some more novel steroidal pyrimidine derivatives and are currently being evaluated for their biological activities.     

Iridium(I)-salicylaldiminato-cyclooctadiene complexes used as catalysts for phenylborylation

Iridium(I) salicylaldiminato-cyclooctadiene complexes, Ir(-o-O-C₆H₄-CHN-R)(cod) (R = CH₂Ph (1), Ph (2); cod = 1,5-cyclooctadiene), have been prepared, characterized and used as catalysts for arylborylation via C-H activation. With 1 as a catalyst, isolated yields of up to 91% has been achieved for the borylation of benzene by bis(pinacolato)diboron in the presence of tetra-2-pyridinylpyrazine and an ionic liquid. The catalytic system could be recycled for at least three times without loss of activity.