全文获取类型
收费全文 | 1592篇 |
免费 | 65篇 |
国内免费 | 7篇 |
专业分类
化学 | 1318篇 |
晶体学 | 10篇 |
力学 | 14篇 |
数学 | 73篇 |
物理学 | 249篇 |
出版年
2023年 | 15篇 |
2022年 | 12篇 |
2021年 | 19篇 |
2020年 | 25篇 |
2019年 | 26篇 |
2018年 | 26篇 |
2017年 | 16篇 |
2016年 | 42篇 |
2015年 | 33篇 |
2014年 | 48篇 |
2013年 | 84篇 |
2012年 | 142篇 |
2011年 | 111篇 |
2010年 | 61篇 |
2009年 | 71篇 |
2008年 | 113篇 |
2007年 | 122篇 |
2006年 | 125篇 |
2005年 | 95篇 |
2004年 | 77篇 |
2003年 | 59篇 |
2002年 | 42篇 |
2001年 | 26篇 |
2000年 | 23篇 |
1999年 | 12篇 |
1998年 | 14篇 |
1997年 | 10篇 |
1996年 | 9篇 |
1995年 | 13篇 |
1994年 | 7篇 |
1993年 | 9篇 |
1992年 | 8篇 |
1991年 | 8篇 |
1990年 | 8篇 |
1988年 | 12篇 |
1986年 | 6篇 |
1985年 | 15篇 |
1984年 | 15篇 |
1983年 | 8篇 |
1982年 | 12篇 |
1981年 | 8篇 |
1980年 | 5篇 |
1979年 | 10篇 |
1978年 | 10篇 |
1977年 | 7篇 |
1976年 | 7篇 |
1975年 | 5篇 |
1974年 | 5篇 |
1971年 | 6篇 |
1969年 | 4篇 |
排序方式: 共有1664条查询结果,搜索用时 31 毫秒
141.
Usuki H Yamamoto Y Arima J Iwabuchi M Miyoshi S Nitoda T Hatanaka T 《Organic & biomolecular chemistry》2011,9(7):2327-2335
A new S9 family aminopeptidase derived from the actinobacterial thermophile Acidothermus cellulolyticus was cloned and engineered into a transaminopeptidase by site-directed mutagenesis of catalytic Ser(491) into Cys. The engineered biocatalyst, designated aminolysin-A, can catalyze the formation of peptide bonds to give linear homo-oligopeptides, hetero-dipeptides, and cyclic dipeptides using cost-effective substrates in a one-pot reaction. Aminolysin-A can recognize several C-terminal-modified amino acids, including the l- and d-forms, as acyl donors as well as free amines, including amino acids and puromycin aminonucleoside, as acyl acceptors. The absence of amino acid esters prevents the formation of peptides; therefore, the reaction mechanism involves aminolysis and not a reverse reaction of hydrolysis. The aminolysin system will be a beneficial tool for the preparation of structurally diverse peptide mimetics by a simple approach. 相似文献
142.
Satoshi Masaki 《Journal of Differential Equations》2011,251(11):3028-3062
We consider the semiclassical Schrödinger-Poisson system with a special initial data of WKB type such that the solution of the limiting hydrodynamical equation becomes time-global in dimensions at least three. We give an example of such initial data in the focusing case via the analysis of the compressible Euler-Poisson equations. This example is a large data with radial symmetry, and is beyond the reach of the previous results because the phase part decays too slowly. Extending previous results in this direction, we justify the WKB approximation of the solution with this data for an arbitrarily large interval of R+. 相似文献
143.
Hayashi M Sasano Y Nagasawa S Shibuya M Iwabuchi Y 《Chemical & pharmaceutical bulletin》2011,59(12):1570-1573
A highly active organocatalyst for alcohol oxidation has been developed. 9-Azanoradamantane N-oxyl (Nor-AZADO 4), constituting an unhindered, stable nitroxyl radical, exhibits superior catalytic activity to 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) and AZADOs in the oxidation of alcohols to their corresponding carbonyl compounds. 相似文献
144.
The effect of temperature on the surface phase behavior of tetradecanoyl N-ethanolamide (NHEA-14) in Langmuir monolayers at the air-water interface has been investigated by film balance and Brewster angle microscopy (BAM). It has been observed that dendritic domains are formed in the coexistence region between liquid-expanded (LE) and liquid-condensed (LC) phases at different temperatures. At 10 and 15°C, the domains are four-armed dendrites having wide arms which have a tendency to be fractal while growing in size. At 20°C, five-armed dendritic domains are formed. At a temperature higher than 20°C, the domains are mainly six-armed dendrites having very narrow and sharp arms. The formation of dendritic domains should be due to the presence of interfacial hydrogen bonding among the head groups of the amphiphile. Increased dehydration of the head groups with an increase in the temperature should be responsible for the temperature dependency of the dendritic domain shapes in the monolayers of NHEA-14. 相似文献
145.
Reichhardt C Uchida M O'Neil A Li R Prevelige PE Douglas T 《Chemical communications (Cambridge, England)》2011,47(22):6326-6328
Biomimetic chemistry offers new approaches to supramolecular materials synthesis and assembly. We have demonstrated that an assembled viral protein cage, comprising an organic core-shell structure, can be used as a template for the size constrained synthesis of Fe(2)O(3). Particle nucleation is directed by the inner scaffold protein layer, while the size constraints are determined by the outer capsid layer. 相似文献
146.
Journal of Theoretical Probability - Let $$\{X_t\}_{t \ge 0}$$ be a transient $$\alpha $$ -stable process on $${\mathbb {R}}^d$$ and denote by H its generator. We consider the perturbation of the... 相似文献
147.
Dynamical features of hydrogen bonds in methanol–water mixtures have been analysed in terms of lifetime in the wide range of conditions, including supercritical states, using a molecular dynamics simulation with flexible potential models. Hydrogen bond characteristics in methanol–water mixtures were investigated by considering the combination of molecular species and donor–acceptor of hydrogen-bonded molecules. The hydrogen bond lifetimes mainly depend on temperature, and those in supercritical condition were about 1/10th of that at ambient condition. Focusing on the composition dependence of the hydrogen bond lifetime, the unique behaviour of that resulting from hydration structure was observed. Moreover, the molecular combination, which showed the largest hydrogen bond lifetime, was different for ambient and high temperature and high pressure conditions. The relationship between hydrogen bond lifetime and molar volume was also calculated to discuss the hydrogen bond lifetime in terms of the collision frequency of molecules and the intermolecular distance. 相似文献
148.
Noriyuki Yonezawa Toshio Kanoe Kazuhiko Saigo Masaki Hasegawa 《Journal of polymer science. Part A, Polymer chemistry》1993,31(3):667-673
Two new types of polyamides having anti head-to-tail hydroxycinnamic acid dimer component in the main chain were synthesized. Their thermal degradation behavior was investigated by TG-DSC analysis in comparison with those of their model compounds and the polyamides derived from anti head-to-head coumarin dimer. The key reactions in the thermal degradation were clarified to be lactonization and cyclic imide formation. The polyamide, derived from 4-hydroxycinnamic acid dimer and hexamethylenediamine, showed good heat stability. © 1993 John Wiley & Sons, Inc. 相似文献
149.
Akira Kaito Masaki Shimomura Michiaki Akaba Shuichi Nojima 《Journal of Polymer Science.Polymer Physics》2007,45(15):1959-1969
Real‐time small‐angle X‐ray scattering (SAXS) measurement using synchrotron radiation was applied to study the lamellar structural changes in miscible crystalline polymer blends of poly(1,4‐butylene succinate) (PBSU) and poly(vinylidene fluoride) (PVDF) during melting and crystallization processes. The lamella of PBSU is either included in the interlamellar region of PVDF (interlamellar inclusion structure), or rejected from the interlamellar region of PVDF (interlamellar exclusion structure). The two lamellar structures coexists in the melt‐quenched samples of the PBSU/PVDF = 30/70 blend. Only the interlamellar exclusion structure exists in the drawn films of the PBSU/PVDF = 30/70 blend. The real‐time SAXS results show that the interlamellar exclusion structure in these samples is irreversibly transformed into the interlamellar inclusion structure by heating the sample above the melting temperature of PBSU and that the PBSU chains are crystallized between the lamellae of PVDF during the cooling process. The factors controlling the lamellar structural changes are possibly a balance of the miscibility and the chain exclusion by tie‐molecules and/or the chain diffusion under confinement by the lamellae of PVDF with higher melting temperature. © 2007 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 45: 1959–1969, 2007 相似文献
150.
One of the important features of eukaryotic cells is the presence of intracellular compartments, organelles. Each organelle plays an essential role in the organelle-specific function; each cooperates with others for maintaining the vital activity of living cells. To analyze the organelle-specific functions, researchers have used many fluorescent and luminescent reporter proteins extensively. The reporter proteins have provided unprecedented insights into the movement of proteins and their interactions in the organelles. In this review, we summarize recently validated methods for visualizing protein localization, dynamics and protein-protein interactions, and for identifying a series of proteins localized in organelles using newly developed reporter proteins. 相似文献