Strategic utilization of catalytic metathesis and photo-thermal metathesis in caged polycyclic frames

Highly functionalized cage compounds have been prepared via cross-metathesis (CM) using Grubbs modified N-tolyl catalyst 7. A strategic utilization of photo-thermal metathesis and catalytic metathesis sequence for the synthesis of functionalized caged molecules has been demonstrated.     

Multiferroic magnetoelectric coupling and relaxor ferroelectric behavior in 0.7BiFeO3-0.3BaTiO3 nanocrystals

The structural, microstructural, polarization, magnetization, dielectric constant, and relaxor characteristics of 0.7BiFeO₃-0.3BaTiO₃ (BF-BT) nanocrystals have been studied. BF-BT nanocrystals were prepared by a chemical route using polyvinyl alcohol as surfactant. The phase structure is confirmed by X-ray diffraction and average particle size by transmission and scanning electron microscopy. The magnetoelectric coupling is studied by polarization hysteresis loops under the influence of applied magnetic field and the phase transition anomaly. The diffuse phase transition is studied by modified Curie-Weiss law and relaxor characteristics by Vogel-Fulcher relation.     

Improvement of some pharmaceutical properties of mycophenolate mofetil (MMF) by para sulphonatocalix[4]resorcinarene inclusion complex

As a part of our investigations to unfold the chemistry of calixresorcinarene, we have focused on the formation of inclusion complex of a poorly soluble (43 μg ml^?1 at pH 7) drug mycophenolate mofetil (MMF) an immunosuppressive agent and an inosine monophosphate dehydrogenase (IMPDH) inhibitor with para sulphonatocalix[4]resorcinarene (PSC4R). The complete complexation of the drug was achieved after 48 h of stirring with para sulphonatocalix[4]resorcinarene(PSC[4]R) in water and evaporation of water yield the solid complex. The interaction between para sulphonatocalix[4]resorcinarene(PSC[4]R) and MMF in solid state inclusion complexes was accomplished by aqueous phase solubility studies, Thermal Analysis, HPLC, PXRD, FT-IR, and UV–Vis spectroscopy. The results of the phase solubility experiments are in good conformity to signify the formation of 2:1 PSC4R: MMF complexes. The purpose of this study was to enhance solubility and resulting in high dissolution rate and bioavailability of this essentially water insoluble drug. The results of the in vivo study shows that there is a remarkable change in the toxicity of the pure drug MMF and complex did not produce any mortality up to 2200 mg kg^?1.     

XRD and RBS study of annealing effects in titanium implanted a-silicon films

We have used ion implantation of 30 keV⁴⁸Ti⁺ ions into a-Si films at nominal doses of 10²⁰-10²¹ ions/m² to fabricate coherent silicide layers. Characterization of these layers and study of their annealing behaviour were carried out using XRD and RBS techniques. We find that the layers are a mixture of Ti₅Si₄, TiSi, TiSi₂ and Si. On annealing at relatively lower temperatures (up to ～ 300° C), predominant silicide phases present in the layer are Ti-rich, such as Ti₅Si₄ and TiSi. At higher temperatures, the Ti-rich layer has a tendency to consume unreacted Si from the film and to form a predominantly Si-rich silicide layer. A structure of silicon different from the diamond cubic structure is noticed in these implanted layers.     

Theoretical investigation of phase transition properties in strontium chalcogenides using potential model

The Born–Mayer potential has been employed to predict the phase transition pressure in four strontium monochalcogenides, namely, SrO, SrS, SrSe, and SrTe, which crystallize in the NaCl (B1) phase and with the application of pressure, transforms to the CsCl (B2) phase. The compression, bulk modulus and the first-order pressure derivative of bulk modulus have also been calculated and compared with the available experimental and other theoretical results. The calculated values of transition pressure and other elastic properties predict that the hardness and strength parameters depend on the crystal structure and have the different values for different structures.     

Infinite Dimensional Bicomplex Spectral Decomposition Theorem

This paper presents a bicomplex version of the Spectral Decomposition Theorem on infinite dimensional bicomplex Hilbert spaces. In the process, the ideas of bounded linear operators, orthogonal complements and compact operators on bicomplex Hilbert spaces are introduced and treated in relation with the classical Hilbert space M′ imbedded in any bicomplex Hilbert space M.     

Experimental study on novel phase change composites for thermal energy storage

Journal of Thermal Analysis and Calorimetry - In this study, beeswax is studied as a phase change material (PCM) to store heat due to its high latent heat. The disadvantages of using beeswax were...     

Development and validation of consensus machine learning-based models for the prediction of novel small molecules as potential anti-tubercular agents

Molecular Diversity - Tuberculosis (TB) is an infectious disease and the leading cause of death globally. The rapidly emerging cases of drug resistance among pathogenic mycobacteria have been a...