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991.
Vakhtang Kokilashvili Mieczysław Mastyło Alexander Meskhi 《Journal of Mathematical Analysis and Applications》2015
The main aim of this paper is to study a general multisublinear operators generated by quasi-concave functions between weighted Banach function lattices. These operators, in particular, generalize the Hardy–Littlewood and fractional maximal functions playing an important role in harmonic analysis. We prove that under some general geometrical assumptions on Banach function lattices two-weight weak type and also strong type estimates for these operators are true. To derive the main results of this paper we characterize the strong type estimate for a variant of multilinear averaging operators. As special cases we provide boundedness results for fractional maximal operators in concrete function spaces. 相似文献
992.
María Cuartero Jonathan Sabaté del Río Pascal Blondeau Joaquín A. Ortuño F. Xavier Rius Francisco J. Andrade 《Analytica chimica acta》2014
The development of a solid-contact potentiometric sensor based on conducting rubbers using a carbon nanotubes ink is described here. Commercial rubbers are turned into conductive ones by a simple and versatile method, i.e. painting an aqueous dispersion of single-walled carbon nanotubes on the polymer surface. On this substrate, both the working ion-selective electrode and the reference electrode are built in order to form an integrated potentiometric cell. As a proof-of-principle, selective potassium electrodes are fully characterized giving comparable performances to conventional electrodes (sensitivity, selectivity, stability, linear range, limit of detection and reproducibility). As an application of the rubber-based electrodes, a bracelet was constructed to measure potassium levels in artificial sweat. Since rubbers are ubiquitous in our quotidian life, this approach offers great promise for the generation of chemical information through daily objects. 相似文献
993.
Synthesis and Characterization of New Cross‐like Porphyrin–Naphthalocyanine and Porphyrin–Phthalocyanine Pentads 下载免费PDF全文
Mário J. F. Calvete João P. C. Tomé José A. S. Cavaleiro 《Journal of heterocyclic chemistry》2014,51(Z1):E202-E208
Synthesis and characterization of new cross‐like porphyrin–naphthalocyanine and porphyrin–phthalocyanine systems, where one naphthalocyanine and one phthalocyanine are the central moieties of the pentads, respectively, and in both cases substituted with four porphyrin units, in a cross‐shape structure. Porphyrin–naphthalonitrile and porphyrin–phthalonitrile adducts were prepared from the reaction of 5‐(p‐hydroxyphenyl)‐10,15,20‐triphenylporphyrin with the appropriate dihalogenated naphthalonitrile or phthalonitrile, respectively, to provide a straightforward cyclotetramerization in the presence of metallic magnesium, used as template. Spectroscopic characterization and initial photophysical assessment are also reported. 相似文献
994.
Rin Jang Ki Hun Kim Shabi Abbas Zaidi Won Jo Cheong Myeong Hee Moon 《Electrophoresis》2011,32(16):2167-2173
In this study, an open‐tubular capillary electrochromatography (OT‐CEC) column with a monolithic layer of molecularly imprinted polymer (MIP) based on methacrylic acid, ethylene glycol dimethacrylate, and 4‐styrenesulfonic acid was utilized for the simultaneous separation and characterization of phospholipid (PL) molecular structures by interfacing with electrospray ionization‐tandem mass spectrometry (ESI‐MS‐MS). Introducing an MIP‐based monolith along with charged species at the OT column made it possible to separate PL molecules based on differences in head groups and acyl chain lengths in CEC. For the interface of OT‐CEC with ESI‐MS‐MS, a simple nanospray interface utilizing a sheath flow was developed and the resulting OT‐CEC‐ESI‐MS‐MS was able to separate PL standards (phosphatidylserines, phosphatidylethanolamines, phosphatidylglycerols, phosphatidic acid, and lysophosphatidylglycerols). The developed method was applied to human urinary lipid extracts, and resulted in the separation and structural identification of 18 molecules by data‐dependent collision‐induced dissociation. 相似文献
995.
Understanding how glycosylation affects protein structure, dynamics, and function is an emerging and challenging problem in biology. As a first step toward glycan modeling in the context of structural glycobiology, we have developed Glycan Reader and integrated it into the CHARMM-GUI, http://www.charmm-gui.org/input/glycan. Glycan Reader greatly simplifies the reading of PDB structure files containing glycans through (i) detection of carbohydrate molecules, (ii) automatic annotation of carbohydrates based on their three-dimensional structures, (iii) recognition of glycosidic linkages between carbohydrates as well as N-/O-glycosidic linkages to proteins, and (iv) generation of inputs for the biomolecular simulation program CHARMM with the proper glycosidic linkage setup. In addition, Glycan Reader is linked to other functional modules in CHARMM-GUI, allowing users to easily generate carbohydrate or glycoprotein molecular simulation systems in solution or membrane environments and visualize the electrostatic potential on glycoprotein surfaces. These tools are useful for studying the impact of glycosylation on protein structure and dynamics. 相似文献
996.
997.
Huang C Soenen SJ Rejman J Lucas B Braeckmans K Demeester J De Smedt SC 《Chemical Society reviews》2011,40(5):2417-2434
Stimuli-responsive electrospun nanofibers are gaining considerable attention as highly versatile tools which offer great potential in the biomedical field. In this critical review, an overview is given on recent advances made in the development and application of stimuli-responsive fibers. The specific features of these electrospun fibers are highlighted and discussed in view of the properties required for the diverse applications. Furthermore, several novel biomedical applications are discussed and the respective advantages and shortcomings inherent to stimuli-responsive electrospun fibers are addressed (136 references). 相似文献
998.
Gupta R Sheth DM Boone TK Sevilla AB Fréchette J 《Langmuir : the ACS journal of surfaces and colloids》2011,27(24):14923-14929
Pinning of the triple contact line adversely affects electrowetting on dielectric. Electrowetting response of substrates with contact angle hysteresis ranging from 1° to 30° has been characterized, and the results are interpreted within the framework of electromechanics corrected for pinning. The relationship between contact angle hysteresis, threshold potential for liquid actuation, and electrowetting hysteresis is quantified. Our results demonstrate that a modified electrowetting equation, based on balance of forces (including the pinning forces) acting on the triple contact line and on the drop, describes the electrowetting response of substrates with significant contact angle hysteresis. Finally, the surface properties of PDMS Sylgard 184 were found to be influenced by the electric field. 相似文献
999.
Martins GV Mano JF Alves NM 《Langmuir : the ACS journal of surfaces and colloids》2011,27(13):8415-8423
In this paper, we describe the construction and characteristics of thermoresponsive, thin nanostructured films prepared by layer-by-layer sequential assembly of chitosan-graft-NIPAAm and alginate. FTIR and (1)H NMR spectra have confirmed the introduction of NIPAAm moieties onto the chitosan backbone. The LCST of the synthesized copolymer was found to be around 31-33 °C. The formation of the polyelectrolyte multilayers containing the copolymer and alginate was followed in situ by quartz crystal microbalance with dissipation monitoring technique and ex situ by UV-vis measurements. Our results revealed the linear increase of the multilayer film growth and the influence of the presence of salt. Moreover, AFM analysis has confirmed that PNIPAAm is able to reconform upon temperature swaps even when combined with other layers in a polyelectrolyte multilayer, demonstrating that the nanoassemblies are thermoresponsive. Preliminary results showed that, upon reducing culture temperature below PNIPAAm LCST, a gradual detachment of cell sheets from these PNIPAAm-based coatings has occurred. 相似文献
1000.
Mafalda Cruz SarraguçaSandra Oliveira Soares João Almeida Lopes 《Vibrational Spectroscopy》2011,56(2):184-192
The analytical determination of aminoglycosides in pharmaceutical formulations is very difficult due to the lack of chromophores or fluorophores. Several analytical methods have been developed along the years mainly based on derivatization reactions. The European Pharmacopeia (EP) and the United States Pharmacopeia (USP) describe a microbiological assay to the quantification of aminoglycosides. Near infrared spectroscopy (NIRS) can be used alternatively to analyse aminoglycosides without the need of derivatization reactions or other type of sample processing. A new NIRS based method was developed for the analysis of the aminoglycoside antibiotic neomycin. The method was developed with samples based on a commercial formulation containing neomycin sulphate and three excipients: lactose, talc and magnesium stearate. Synthetic and doped samples were manufactured for this purpose. Three lots of a commercial solid formulation were also used to assess the validity of the method to quantify neomycin sulphate in the industrial pharmaceutical product. The method proposes measurements in reflectance mode using a Fourier-transform near infrared (FT-NIR) spectrometer. Partial least squares regression was the multivariate method adopted to calibrate the NIR spectra with the neomycin sulphate mass fraction. The concentration of neomycin sulphate present in the commercial samples was confirmed by HPLC with pre-column derivatization with phenylisocyanate. Results show that neomycin sulphate was determined successfully in the commercial samples using the method calibrated with the doped samples (mass fraction error of 6.6%). Moreover, the synthetic samples were found to be unqualified to develop the method, producing a biased calibration. 相似文献