pH responsive self-healing hydrogels formed by boronate-catechol complexation

Here we report the synthesis and characterization of pH-responsive, self-healing hydrogels based on boronate-catechol complexation.     

Machine Learning Informs RNA-Binding Chemical Space**

Small molecule targeting of RNA has emerged as a new frontier in medicinal chemistry, but compared to the protein targeting literature our understanding of chemical matter that binds to RNA is limited. In this study, we reported R epository O f BI nders to N ucleic acids (ROBIN), a new library of nucleic acid binders identified by small molecule microarray (SMM) screening. The complete results of 36 individual nucleic acid SMM screens against a library of 24 572 small molecules were reported (including a total of 1 627 072 interactions assayed). A set of 2 003 RNA-binding small molecules was identified, representing the largest fully public, experimentally derived library of its kind to date. Machine learning was used to develop highly predictive and interpretable models to characterize RNA-binding molecules. This work demonstrates that machine learning algorithms applied to experimentally derived sets of RNA binders are a powerful method to inform RNA-targeted chemical space.     

非磁性替代原子对Ce_2Co_(17)居里温度和饱和磁化强度的影响

用真空电弧熔炼法制备了Ce2 Co17-xMx(M =Ga ,Al和Si)化合物。通过X射线衍射和磁性测量手段 ,研究了非磁性替代原子Ga,Al和Si的加入对Ce2 Co17化合物的居里温度和饱和磁化强度的影响 ,其中Si在Ce2 Co17化合物中的固溶度最小 ,并使居里温度和饱和磁化强度下降幅度最大。     

ChemInform Abstract: Ab Initio Study of the Endohedral Complexes of C60, Si60, and Ge60

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.     

ChemInform Abstract: Mechanism of Gas Phase Oxidizing and Reducing Action of N2H4 in the Presence of HO- Ion.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.     

ChemInform Abstract: Crystal Structure of the Binuclear Fluoro Compound Cs3Ga2F9.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.     

ChemInform Abstract: Structural and Thermal Properties of the Tetragonal Cobalt Manganese Spinels MnxCo3-xO4 (1.4 < x < 2.0).

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.     

ChemInform Abstract: Computational Studies of Atmospheric Chemistry Species. Part 7. An ab initio Study of the N2×××O2 Heterodimer.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.