Total Valuation Rings of Ore Extensions

We consider extensions of a total valuation ring V of a skew field K to the Ore extension K(X;σ, δ) for an endomorphism σ of K and a σ-derivation δ. It is shown that there exists an extension R of V with X ∈ R, such that ${\overline X}$ is transcendental over V/J(V) if and only if (σ,δ) is compatible with V, where ${\overline X} = X + J(R^(1))$ . In the case V is invariant, it is established that there is an invariant extension R of V in K(X;σ,δ) such that ${\overline X}$ is transcendental if and only if σ(a)V = aV and δ(a) ∈ aV for all a ∈ K.     

Geometric Dynamics

A kinematic differential system on a Riemann (or semi-Riemann) manifold induces a Lorentz-Udrite world-force law, i.e., any local group with one parameter (any local flow) on a Riemann (or semi-Riemann) manifold induces the dynamics of the given vector field or of an associated particle, which will be called geometric dynamics.The cases of Riemann-Jacobi or Riemann-Jacobi-Lagrange structures are imposed by the behavior of an external tensor field of type (1,1). The case of the Finsler-Jacobi structure appears if the initial metric is chosen such that the energy of the given vector field is constant (Sec. 1). At the end of Sec. 1 are formulated open problems regarding some extensions of geometric dynamics.Adequate structures on the tangent bundle describe the geometric dynamics in the Hamilton language (Sec. 2).Section 3 proves the existence of a Finsler-Jacobi structure induced by an almost contact metric structure.The theory is applied to electromagnetic dynamical systems (the starting point of our theory), offering new principles of unification of the gravitation and the electromagnetism. Also, here, one enounces open problems regarding the geometric dynamics induced by the electric intensity and magnetizing force (Sec. 4).From the geometrical point of view, we create a wider class of Riemann-Jacobi, Riemann-Jacobi-Lagrange, or Finsler-Jacobi manifolds ensuring that all trajectories of a given vector field are geodesics. Having T₁M²ⁿ⁺¹ in mind, the problem of creating a wider class of Riemannian manifolds, in which there exists a vector field such that (1) all trajectories of the vector field are geodesics; (2) the flow defined by is incompressible; (3) the condition which corresponds to the property that is the associate vector field of the contact structure is satisfied;was studied intensively by S. Sasaki. The results were not satisfactory, but Sasaki discovered (, , )-structures [10].AMS Subject Classification (1991): 70H35, 53C22, 58F25, 83C22     

Shaping of intense ion beams into hollow cylindrical form

A specifically tailored plasma lens could shape a high-energy, heavy-ion beam into the form of a hollow cylinder without loss of beam intensity. It has been experimentally confirmed that both a positive as well as a negative radial gradient of the current density in the active plasma lens can be the underlying principle. Calculations were performed that yield the ideal current density distribution for both cases. A numerical simulation of an experiment with an intense ion beam highlights that the shaping of the beam increases the achievable compression in a lead sample.     

Sharp Lower Bounds for the Dimension of the Global Attractor of the Sabra Shell Model of Turbulence

In this work we derive lower bounds for the Hausdorff and fractal dimensions of the global attractor of the Sabra shell model of turbulence in different regimes of parameters. We show that for a particular choice of the forcing term and for sufficiently small viscosity term ν, the Sabra shell model has a global attractor of large Hausdorff and fractal dimensions proportional to log  ν ⁻¹ for all values of the governing parameter ε, except for ε =1. The obtained lower bounds are sharp, matching the upper bounds for the dimension of the global attractor obtained in our previous work. Moreover, the complexity of the dynamics of the shell model increases as the viscosity ν tends to zero, and we describe a precise scenario of successive bifurcations for different parameters regimes. In the “three-dimensional” regime of parameters this scenario changes when the parameter ε becomes sufficiently close to 0 or to 1. We also show that in the “two-dimensional” regime of parameters, for a certain non-zero forcing term, the long-term dynamics of the model becomes trivial for every value of the viscosity. AMS Subject Classifications: 76F20, 76D05, 35Q30     

Metabolic compartmentalization in the human cortex and hippocampus: evidence for a cell- and region-specific localization of lactate dehydrogenase 5 and pyruvate dehydrogenase

Background  

For a long time now, glucose has been thought to be the main, if not the sole substrate for brain energy metabolism. Recent data nevertheless suggest that other molecules, such as monocarboxylates (lactate and pyruvate mainly) could be suitable substrates. Although monocarboxylates poorly cross the blood brain barrier (BBB), such substrates could replace glucose if produced locally.     

A stochastic Lagrangian representation of the three‐dimensional incompressible Navier‐Stokes equations

In this paper we derive a probabilistic representation of the deterministic three‐dimensional Navier‐Stokes equations based on stochastic Lagrangian paths. The particle trajectories obey SDEs driven by a uniform Wiener process; the inviscid Weber formula for the Euler equations of ideal fluids is used to recover the velocity field. This method admits a self‐contained proof of local existence for the nonlinear stochastic system and can be extended to formulate stochastic representations of related hydrodynamic‐type equations, including viscous Burgers equations and Lagrangian‐averaged Navier‐Stokes alpha models. © 2007 Wiley Periodicals, Inc.     

Synthesis, structure determination, and (radio-)fluorination of novel functionalized phosphanes suitable for the traceless Staudinger ligation

An elegant and efficient synthesis approach for the preparation of novel benzoate and nicotinate containing phosphanes is presented. This reaction path has a broad substrate scope. Thus, various functionalized phosphanes were obtained in high yields using an esterification procedure under Steglich conditions. A facile blocking of the phosphorus atom with BH₃ was carried out. BH₃ as easily insertable and removable protecting group enables a further derivatization of the benzoate residue. The prepared phosphane derivatives proved to be valuable labeling building blocks for the implementation of a bioorthogonal (radio-)fluorination strategy and were applied for labeling purposes using the traceless Staudinger ligation. For this purpose, a selection of azide-functionalized small organic and bioactive sample molecules was prepared. Furthermore, a mild and selective (radio-)fluorination of these derivatives is demonstrated adopting this bioorthogonal ligation method.     

Benzene triradicals: stabilization or destabilization?

A new group additivity scheme has been developed to evaluate the stabilization/destabilization effects of benzene triradicals. It is shown that benzene triradicals manifest a significant destabilization effect and not stabilization effect as previously thought.