Phytochemical Characterization of Olea europaea L. Cultivars of Cilento National Park (South Italy) through NMR-Based Metabolomics

Olea europaea germplasm is constituted by a huge number of cultivars, each one characterized by specific features. In this context, endemic cultivars evolved for a very long period in a precise local area, developing very specific traits. These characteristics include the production and accumulation of phytochemicals, many of which are also responsible for the nutraceutical value of the drupes and of the oils therefrom. With the aim of obtaining information on the phytochemical profile of drupes of autochthonous cultivars of Cilento, Vallo di Diano and Alburni National Park, a metabolomics-based study was carried out on 19 selected cultivars. Multivariate data analysis of ¹H-NMR data and 2D NMR analyses allowed the rapid identification of metabolites that were qualitatively and/or quantitatively varying among the cultivars. This study allowed to identify the cultivars Racioppella, Guglia, Pizzulella, Oliva amara, and Racioppa as the richest in health-promoting phenolic compounds. Furthermore, it showed a significant variability among the different cultivars, suggesting the possibility of using metabolic fingerprinting approaches for cultivar differentiation, once that further studies aimed at assessing the influence of growing conditions and environmental factors on the chemical profiles of single cultivars are carried out.     

Non-invasive characterisation of SIX Japanese hand-guards (tsuba)

In this work we present a systematic study of Japanese sword hand-guards (tsuba) carried out by means of non-invasive techniques using neutrons. Several tsuba from different periods, belonging to the Japanese Section of the Stibbert Museum, were analysed using an innovative approach to characterise the bulk of the samples, coupling two neutron techniques, namely Time of Flight Neutron Diffraction (ToF-ND) and Nuclear Resonance Capture Analysis (NRCA). The measurements were carried out on the same instrument: the INES beam-line at the ISIS spallation pulsed neutron source (UK). NRCA analysis allows identifying the elements present in the sample gauge volume, while neutron diffraction is exploited to quantify the phase distribution and other micro-structural parameters of the metal specimen. The results show that all samples are made of high-quality metal, either steel or copper alloy, with noticeable changes in composition and working techniques, depending on the place and time of manufacturing.     

Quantum de Sitter algebra and some possible applications in cosmology

I summarize results recently obtained in collaboration with Amelino-Camelia, Bruno and Mandanici (preprint University of Rome “La Sapienza”, August, 2005) that concern an analysis of the path of a massless particle in a q-de Sitter space-time and an approximation scheme suitable for the corresponding analysis in a quantum FRW Universe. On the basis of some arguments in the quantum-gravity literature, the q deformation parameter is assumed to depend on both the Planck scale and the curvature, leading to results that are significantly different from those of other studies of Planck-scale effects in cosmology, where the possibility of an interplay between curvature and Planck scale was ignored. Presented at the International Colloquium “Integrable Systems and Quantum Symmetries”, Prague, 16–18 June 2005.     

On divisible designs and local algebras

We study the action of the group PGL(m,A) on the projective space PG(m − 1,A) over a finite commutative local algebra A in order to construct a class of divisible designs, denoted by D_m(d,A), which is the classical one of 2-designs (of points and of flats of fixed projective dimension) in the case where A is a field. We also study the constructed divisible designs with particular care for the case where d = m − 1. © 1995 John Wiley & Sons, Inc.     

Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement

Derivatives of the new ring system pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine were synthesized from the corresponding angular isomers, through a Dimroth rearrangement, in quantitative yields. Preliminary computational studies demonstrated that this class of compounds could be a good candidate as DNA intercalating agents.     

The site-selectivity of cycloadditions of nitrile oxides to β-aminocinnamonitriles. A remarkable solvent dependence

Cycloadditions of nitrile oxides to N-mono and unsubstituted β-aminocinnamonitriles are remarkably affected by the hydrogen acceptor ability of the solvent. Addition to C ? N bond predominates in non and weak hydrogen bond acceptor solvents because of the assistance of favourable hydrogen bonding effects. In strong hydrogen bond acceptor solvents the assistance is fully relieved and the regular addition to C ? C bond becomes prevalent.     

Acoplanar (e+e−) pairs and radiative corrections

Further proof is given for the inadequacy of the peaking approximation in first-order radiative corrections, via the observation of 429 non-coplanar (e⁺e^?) events. The energy dependence of this effects is measured in the s-range 1.44 to 9.0 GeV², and represents another proof of the validity of QED.