Synthesis,Structure and Norbornene Polymerization Catalyzed by Bis{1-[[(3- ethyl-6-methyl-2-pyridinyl)imino]methyl- enyl]-2-naphthalenolato-N,O}nickel( Ⅱ)

The title complex bis{1-[[(3-ethyl-6-methyl-2-pyridinyl)imino]methylenyl]- 2-na- phthalenola-to-N,O}nickel has been synthesized by the reaction of 1-[[(3-ethyl-6-methyl-2- pyridinyl) imino] methylenyl]-2-naphthalenol with Ni(CH3 COO)2 ·4H2 O, and characterized by IR spectrum and single-crystal X-ray diffraction analysis. The crystal belongs to the orthorhombic system, space group Pbca with a = 11.100(2), b = 15.900(3), c = 18.000(4), V = 3176.8(11)3, C38 H34 N4 NiO2, Mr = 637.40, Z = 4, Dc = 1.333 g/cm3, μ = 0.651 mm-1, F(000) = 1336, the final R = 0.0783 and wR = 0.2119. This title compound was investigated for the catalytic behavior towards norbornene(NB) vinyl addition polymerization. And the complex exhibited good catalytic activity to catalyze norbornene polymerization using MAO as a cocatalyst.     

Synthesis,Structure and Norbornene Polymerization Catalyzed by Bis{(2-benzhydryl-4,6-dimethyl-phenyl)-(3,5-di-tert-butyl-2-methyl-benzylidene)-amine-N,O}nickel(Ⅱ)

The title complex bis{(2-benzhydryl-4,6-dimethyl-phenyl)-(3,5-di-tert-butyl-2-methyl-benzylidene)-amine-N,O}nickel has been synthesized by the reaction of(2-benzhydryl-4,6-dimethyl-phenyl)-(3,5-di-tert-butyl-2-methyl-benzylidene)-amine with Ni(CH_3COO)_2·4H_2O, and characterized by IR spectrum and single-crystal X-ray diffraction analysis. The crystal belongs to the monoclinic system, space group P2_1/c with a = 12.373(4), b = 18.434(7), c = 27.814(10) ?, β = 92.291(6)o, V = 6339(4) ?~3, C7 2H8 0N2 Ni O_2, M_r = 1064.09, Z = 4, D_c = 1.115 g/cm~3, μ = 0.350 mm~(-1), F(000) = 2280, the final R = 0.0846 and wR = 0.2926(I 2s(I)). This title compound was used as homogeneous catalysis of polymerization of norbornene, and the complex exhibited good catalytic activity to catalyze norbornene polymerization using MAO as a cocatalyst.     

Synthesis,Structure and Norbornene Polymerization Activity of a Novel Palladium(Ⅱ) Complex with N,OBis{1-[[(3-methyl-pyridin-2-yl)amino]methyl-phenyl]-2-hydroxy-3,5-di-tert-butylphenol} Ligand

The title complex bis{1-[[(3-methyl-pyridin-2-yl) amino] methyl-phenyl]-2-hydroxy-3,5-di-tert-butylphenol} palladium(C_(42)H_(56)O_2N_4Pd) has been synthesized by the reaction of 1-[[(3-methyl-pyridin-2-yl)amino]methyl-phenyl]-2-hydroxy-3,5-di-tert-butylphenol with Pd(OAc)_2, and was characterized by IR and elemental analyses(C, H, N). Single-crystal X-ray diffraction analysis of the complex revealed an almost parallelogram geometry of the metal center, space group P1 with a = 12.3870(13), b = 12.9673(12), c = 14.3998(4) ?, α = 67.53(2), β = 75.34(2), γ = 86.89(3)°, V = 2065.5(3) ?~3, M_r = 773.32, Z = 2, D_c = 1.243 g/cm~3, μ = 0.489 mm~(-1), F(000) = 816, the final R = 0.0649 and wR = 0.1567. The compound was investigated for the catalytic behavior towards norbornene(NB) vinyl addition polymerization. And the complex exhibits high catalytic activities up to 1.668 × 10~7 g of PNB(mol of Pd)~(-1) h~(-1) with high monomer conversion using methylaluminoxane(MAO) as the cocatalyst.     

Synthesis,Structure and Norbornene Polymerization Activity of a Novel Palladium(Ⅱ) Complex with N,N-bis(2-benzoyl-3-oxobutane)-trans-1,2-diaminocyclohexane Ligand

The title complex N,N-bis(2-benzoyl-3-oxobutane)-trans-1,2-diaminocyclohexane-palladium(C28H28N2PdO4) has been synthesized by the reaction of N,N-bis(2-benzoyl-3-oxobutane)-trans-1,2-diamino-cyclohexane with PdCl2,and characterized by elemental analysis,IR spectrum,WAXD and TG.The spatial structures of the complex have been confirmed by single-crystal X-ray diffraction analysis.The compound crystallizes in the monoclinic system,space group C2/c with a = 29.763(6),b = 10.320(2),c = 18.921(4) ,β = 102.75(3)°,V = 5668(2) 3,C28H28N2PdO4·CH3OH,Mr = 594.97,Z = 8,Dc = 1.394 g/cm3,μ(MoKα) = 0.694 mm-1,F(000) = 2448,T = 293(2) K,R = 0.0572 and wR = 0.1347(I 2(I)).The compound was investigated for the catalytic behavior towards norbornene(NB) vinyl addition polymerization.And the palladium complex showed excellent catalytic activity up to 9.97×106 g of PNB(mol of Pd)-1 h-1 with high monomer conversion using methylaluminoxane(MAO) as a cocatalyst.     

Synthesis, Structure and Norbornene Polymerization Catalyzed by Palladium Complex Bearing the 1,3-Diphenyl-2-((quinolin-8-ylamino)-methylene)-propane-1,3-dione Ligand

The title complex 1,3-diphenyl-2-((quinolin-8-ylamino)methylene)propane-1,3-dione-palladium was synthesized by the reaction of 1,3-diphenyl-2-((quinolin-8-ylamino)-methylene)propane-1,3-dione with PdCl2 , and characterized by IR spectrum and single-crystal X-ray diffraction analysis. The crystal belongs to the orthorhombic system, space group P21212 with a = 21.838(4), b = 8.3952(17), c = 11.497(2), V = 2107.9(7)3 , C25H17ClN2O2Pd, Mr = 519.26, Z = 4, Dc = 1.636 g/cm3 , μ = 1.032 mm-1 , F (000) = 1040, the final R = 0.0307 and wR = 0.0778. This compound was investigated for the catalytic behavior towards norbornene (NB) vinyl addition polymerization. And the complex exhibits excellent catalytic activities up to 2.18×108 g of PNB (mol of Pd)-1 h-1 with high monomer conversion using methylaluminoxane (MAO) as the cocatalyst.     

Synthesis,Structure and Norbornene Polymerization Catalyzed by Nickel(Ⅱ) Complex Bearing N,O-bis(1-(6-ethylpyridin-2-ylimino)-methylenyl)naphthalen-2-ol Ligand

The title complex bis{1-{[(6-ethyl-2-pyridinyl)imino]methylenyl}-2-naphthalenolato-N,O}-nickel(Ⅱ)(C36H32N4O2Ni) has been synthesized by the reaction of 1-{[(6-ethyl-2-pyridinyl)imino]methylenyl}-2-naphthalenol with Ni(CH3COO)2·4H2O, and characterized by IR spectrum, elemental analysis and TG. The complicated space structure has been confirmed by single-crystal X-ray diffraction analysis. The crystal belongs to the monoclinic system, space group P21/c with a = 11.410(4), b = 14.382(4), c = 18.121(6) , β = 97.147(6)°, V = 2950.5(16) 3, C36H32N4O2Ni, Mr = 611.37, Z = 4, Dc = 1.376 g/cm3, μ = 0.698 mm-1, F(000) = 1280, the final R = 0.0519 and wR = 0.1493(Ⅰ 2δ(Ⅰ)). This title compound was used as precatalysts for the polymerisation of norbornene. When activated with MAO, the complex exhibited excellent catalytic activity up to 1.98 × 107 g of PNB(mol of Ni)-1 h-1 with high monomer conversion.     

Synthesis,Structure and Catalytic Activity of a Palladium(Ⅱ) Complex Based on 4-Chloro-2-[(6-methyl-pyridin-2-ylimino)-methyl]-phenol Ligand

The title complex bis{4-chloro-2-[(6-methyl-pyridin-2-ylimino)-methyl]-phenol}-palladium(Ⅱ)(C_(26)H_(20)Cl_2N_4O_2Pd) has been synthesized by the reaction of 4-chloro-2-[(6-methylpyridin- 2-ylimino)-methyl]-phenol with Pd(CH_3COO)_2, and characterized by IR spectrum and elemental analysis. Single-crystal X-ray diffraction analysis results further confirmed the molecular structures. The crystal belongs to the monoclinic system, space group P2_1/c with a = 4.1324(2), b = 23.5432(16), c = 11.8943(8) ?, β = 91.238(5)o, V = 1156.93(12) ?~3, C_(26)H_(20)Cl_2N_4O_2Pd, M_r = 597.76, Z = 2, D_c = 1.716 g/cm~3, μ = 1.067 mm~(-1), F(000) = 600, the final R = 0.0247 and w R = 0.0677(I 2σ(I)). In the presence of methylaluminoxane(MAO), the complex exhibits excellent catalytic activities(1.737×10~7 g of PNB(mol of Pd)~(-1)·h~(-1)) in the vinyl polymerization of norbornene.     

Synthesis, Crystal Structure and Catalytic Behavior of 1-Ethyl-3-benyl-imidazolyl Tetranuclear N-Heterocyclic Carbene Silver Bromide

The title complex [Ag(carbene)2]2[Ag2Br4] has been synthesized by the reaction of Ag2O with 1-ethyl-3-benyl-imidazolium bromide in DMSO at room temperature, and characterized by elemental analysis, 1H NMR and single-crystal X-ray diffraction analysis. It crystallizes in triclinic, space group P with a = 10.1597(10), b =11.0646(11), c = 13.0245(14) , α = 102.230(2), β = 90.606, γ = 113.9250(10)o, V = 1300.3(2) 3, Mr = 748.06, Z = 2, Dc = 1.911 g/cm3, μ(MoKα) = 4.60 mm-1 and F(000) = 728. The structure was refined to R = 0.0316 and wR = 0.0835 for 3744 observed reflections with I > 2σ(I). The title compound crystallizes as a centrosymmetric tetranuclear compound. One half of the molecule comprises the asymmetric unit of the structure. The Ag(1) atom is nearly linear or T-shaped when the Ag(1)-Ag(2) interaction is taken into consideration, which is bi-coordinated by two carbene carbon atoms. The Ag(2) atom adopts tetrahedral geometry. The catalytic behavior of the title complex has been investigated, and the results indicate it has a highly catalytic activation for L-lactide polymerization.     

Synthesis,Crystal Structure and Norbornene Polymerization of a Palladium(Ⅱ) Complex Based on Phenoxyimine Ligand

The title complex N,O-bis{2-[[(2,6-benzhydryl-4-methylphenyl)imino]-methyl]-phenol}-palladium(II)(C_(80)H_(64)N_2O_2 Pd) has been synthesized by the reaction of 2-[[(2,6-benzhydryl-4-methylphenyl)imino]-methyl]-phenol with Pd(CH_3COO)_2, and characterized by IR spectrum and elemental analysis. The spatial structure of the complex has been verified by single-crystal X-ray diffraction analysis. The compound belongs to the monoclinic system, space group P21/n with a = 13.492(3), b = 16.924(3), c = 14.135(3) ?, β = 97.84(3)°, V = 3197.4(11) ?~3, C_(80)H_(64)N_2O_2 Pd, Mr = 1191.73, Z = 2, Dc = 1.238 Mg/m~3, μ = 0.339 mm~(-1), F(000) = 1240, T = 293(2) K, the final R = 0.0593 and wR = 0.1192(I 2s(I)). The compound showed excellent catalytic activity up to 1.130 × 10~7 g of PNB(mol of Pd)~(-1)h~(-1) for the addition polymerization of norbornene by using methylaluminoxane(MAO) as a cocatalyst.     

Synthesis,Crystal Structure and Characterization of a Nickel Complex Based on Phenoxyimine Ligand and Catalysis of the Vinyl Polymerization of Norbornene

The title complex N,O-bis{2-[[(2-benzhydryl-4,6-dimethylphenyl)imino]-methyl]-phenol}-nickel(II)(C_(56)H_(48)N_2NiO_2) has been synthesized by the reaction of 2-[[(2-benzhydryl-4,6-dimethylphenyl)mino]-methyl]-phenol with Ni(CH_3COO)_2·4 H_2O, and characterized by elemental analysis and IR spectrum. The spatial structure of the complex has been confirmed by single-crystal X-ray diffraction analysis. The compound belongs to the monoclinic system, space group C2/c with a = 39.035(8), b = 13.276(3), c = 17.679(4) ?, β = 98.06(3)°, V = 9071(3) ?~3, C_(56)H_(48)N_2NiO_2, M_r = 839.67, Z = 8, D_c = 1.230 Mg/m~3, μ = 0.472 mm~(-1), F(000) = 3536, T = 293(2) K, the final R = 0.0675 and w R = 0.1345(I 2s(I)). The compound showed excellent catalytic activity up to 1.268 × 10~7 g of PNB(mol of Ni)~(-1)h~(-1) for the addition polymerization of norbornene by using methylaluminoxane(MAO) as a cocatalyst.     

A Novel Phenoxyimine-based Schiff Base Ligand and Its Mononuclear Nickel(Ⅱ) Complex:Synthesis,Crystal Structure,Norbornene Polymerization and Catalytic Activity

A novel phenoxyimine-based Schiff base ligand and its mononuclear complex [C_(58)H_(52)N_2NiO_2](L = 2-benzhydryl-4-dimethoxy-3,5-dimethyl-salicylaldehyde) has been synthesized and characterized by IR spectrum, elemental analysis, TG, WAXD spectra, ~1H NMR and ~(13)C NMR. In addition, the molecular structure has been measured by single-crystal X-ray diffraction analysis. The crystal belongs to the monoclinic system, space group P2_1/c with a = 14.510(6), b = 18.573(7), c = 20.961(6) ?, β = 123.453(19)°, V = 4713(3) ?~3, M_r = 867.73, Z = 4, D_c = 1.223 g/cm~3, μ = 0.456 mm~(-1), F(000) = 1832, the final R = 0.0685 and wR = 0.1758(I 2σ(I)). The complex was used as homogeneous catalysis of polymerization of norbornene, and the MAO as cocatalyst. The nickel complex exhibited good catalytic activity up to 1.913 × 10~7 g of PNB(mol of Ni)~(-1)h~(-1),and the yields of these reactions depend on the nature of the substituent in the aromatic ring.     

Synthesis and Characterization of a Palladium Complex Supported by Bidentate Ligand and Catalysis of the Vinyl Polymerization of Norbornene

The title complex N,O-bis{[2-[(2,4-dimethylphenyl)imino]-5-methoxyl]-phenol}-palladium(Ⅱ)(CC_(32)H_(32)N_2O_4Pd) has been synthesized by the reaction of 2-[(2,4-dimethylphenyl)imino]-5-methoxyl-phenol with Pd(CH_3COO)_2,and characterized by elemental analysis,IR spectrum and single-crystal X-ray diffraction analysis.The crystal belongs to the monoclinic system,space group P2_1/c with a = 12.058(2),b = 8.3624(17),c = 14.735(3) ?,β = 107.66(3)°,V = 1415.7(5)?~3,C_(32)H_(32)N_2O_4Pd,Mr = 615,Z = 2,D_c = 1.443 Mg/m~3,μ = 0.695 mm~(-1),F(000) = 632,T = 293(2) K,the final R = 0.0514 and w R = 0.1356(I 2s(I)).Under the co-catalysis of methylaluminoxane(MAO),the palladium compound exhibited favorable catalytic activity for the polymerization of norbornene(NB).     

Synthesis,Crystal Structure and Catalytic Activity of a Dinuclear Aluminum Alkyl Complex

Treatment of indolyl-3-aldimines(3-~tBuN=CH)C_8H_5NH with AlMe_3 afforded the deprotonated indolyl aluminum complex cis-[(μ-η~1:η~1-3-~tBuN=CH)C_8H_5NAlMe_2]_2,and its crystal structure was determined by X-ray single-crystal diffraction.The crystal belongs to the orthorhombic system,space group P2_12_12 with a = 14.590(9),b = 15.860(2),c = 13.266(8) A,μ=0.118 mm~(-1),M_r = 512.64,V= 3069.5(3) A~3,Z = 4,D_c= 1.109 g/cm~3,F(000) = 1104,R= 0.0451 and wR = 0.0937 for 4978 observed reflections with I 2σ(I).In addition,the title compound exhibited a high catalytic activity toward the addition of amines to carbodiimide to form guanidines.     

Nickel(Ⅱ) Complex Bearing a Salicylaldimine Ligand:Synthesis,Crystal Structure and Application in Norbornene Polymerization

A novel salicylaldimine ligand and its mononuclear nickel complex [NiL](L = 2-[[[2,6-bis(diphenylmethyl)-4-methylphenyl]imino]methyl]phenol) have been synthesized and characterized by IR spectrum, elemental analysis and thermogravimetry(TG). The molecular structure of the complex has been measured by single-crystal X-ray diffraction analysis. The crystal belongs to the monoclinic system, space group P2_1/n with a = 13.281(3), b = 16.938(3), c = 13.981(3) ?, β = 97.03(3)o, V = 3121.2(11) ?~3, C_(80)H_(64)N_2O_2Ni, M_r = 1144.04, Z = 2, D_c = 1.217 Mg/m~3, μ = 0.361 mm~(-1), F(000) = 1204, the final R = 0.0582 and wR = 0.1108(I 2s(I)). The compound showed excellent catalytic activity up to 12.78 × 10~6 g of PNB(polynorbornene)(mol of Ni)~(-1) h~(-1) for the addition polymerization of norbornene(NB) by using methylaluminoxane(MAO) as a cocatalyst.     

A Dinuclear Cu(Ⅱ)-based Coordination Framework with Two-fold Interpenetrated 3D pcu Topology Displaying Catalytic Activity

A new Cu(Ⅱ) coordination polymer, [Cu2(mip)2(bmix)]n(bmix = 1,4-bis(2-methylimidazole-1-ylmethyl)benzene, H2 mip = 5-methylisophthalic acid), has been hydrothermally synthesized and characterized by elemental analyses, IR, TGA and single-crystal X-ray diffraction. The title compound belongs to the triclinic system, space group P1 with a = 9.435(5), b = 12.241(6), c = 13.666(6), β = 94.396(8)o, V = 1565.5(13) 3, Z = 2, C34H30Cu2N4O8, Mr = 749.70, Dc = 1.590 g/cm3, μ = 1.419 mm-1 and F(000) = 768. The title metal-organic coordination polymer exhibits the first two-fold interpenetrated pcu topological structure assembled by two types of dinuclear copper(Ⅱ) clusters and a flexible bis(imidazole)-based ligand. In addition, the fluorescence and catalytic performances of the complex for the degradation of Congo red azo dye in Fenton-like process were presented.     

Synthesis,Structure and Norbornene Polymerization Activity of a Novel Palladium（ II ） Complex with N,N＇-bis（2-benzoyl-3-oxobutane）-trans-l,2- diaminocyclohexane Ligand

The title complex N,N＇-bis（2-benzoyl-3-oxobutane）-trans-l,2-diaminocyclo- hexane-palladium （C28H28N2PdO4） has been synthesized by the reaction of N,N＇-bis（2- benzoyl-3-oxobutane）-trans-l,2-diamino-cyclohexane with PdCI2, and characterized by ele- mental analysis, IR spectrum, WAXD and TG. The spatial structures of the complex have been confirmed by single-crystal X-ray diffraction analysis. The compound crystallizes in the monoclinic system, space group C2/c with a = 29.763（6）, b = 10.320（2）, c = 18.921（4） A, fl = 102.75（3）°, V = 5668（2） A3, C28H28N2PdO4·CH3OH, Mr = 594.97, Z = 8, Dc = 1.394 g/cm3, μ（MoKa） = 0.694 mm-1, F（000） = 2448, T= 293（2） K, R = 0.0572 and wR = 0.1347 （I〉 2σ（I））. The compound was investigated for the catalytic behavior towards norbornene （NB） vinyl addition polymerization. And the palladium complex showed excellent catalytic activity up to 9.97x 106g of PNB （mol of Pd）-1 h-1 with high monomer conversion using methylaluminoxane （MAO） as a cocatalyst.     

Crystal Structure, Nano-particle Morphology and Interaction with ATP of [ NH3 CH2 CH（ NH2 ） CH3 ]2 [ M（ Ⅵ ） O2 （ OC6 H4 O）2 ] （M = Mo0. 6 W0. 4 ） and Its Activity to Promote DNA Cleavage

The title complex [NH_3CH_2CH(NH_2)CH_3]_2 [M(Ⅵ)O_2(OC_6H_4O)_2](M= Mo_(0.6)W_(0.4))was synthesized via a simple solution-phase chemical route.The determination of single crystal X-ray diffraction revealed that the title compound is crystallized in a monoclinic system with P2(1)/n space group,a=1.0913(10)nm,b=1.0442(10)nm,c=1.8842(19)nm,α=90°,β=96.530(17)°,γ=90°,Z=4,and V=2.133(4)nm3.The mononuclear anionic unit [M(Ⅵ)O2(OC6H4O)2]2-displays chiral pseudo-octahedral [MO_6] coordination geometry and is linked by chiral cations via hydrogen bond and π…π stacking interaction.The transmission electron microscopy images show that the title complex is comprised of nano-particles with diameters ranging from 20 to 50 nm.The NMR study shows the 1H downfield chemical shifts of [NH_3CHaHbCH(NH_2)CH_3] cations in the title complex when it is mixed with adenosine-triphosphate(ATP),and the chemical shift difference between Ha and Hb is increased greatly,and most of the catecholate ligands dissociate from the central metal atoms.The DNA cleavage activity experiment reveals that DNA cleavage promoted by the title complex is lower than that by Na_2MoO_4 which possesses antitumor pro-perty,but higher than that by Na_2WO_4.     

Synthesis,Electrochemical and Fluorescent Properties of a New Zinc(Ⅱ) Complex through Self-assembly Reaction of 2,2'-Bipyridine-3,3'-dicarboxylic Acid

A new Zn(Ⅱ) complex [Zn(Phen)_2(C_(12)H_6O_4N_2)(H_2O)]·3H_2O with 2,2?-bipyridine-3,3?-dicarboxylic acid and 1,10-phenanthroline(Phen) as ligands was synthesized, and the crystal data are as follows: monoclinic, space group P2_(1/n), a=12.5581(11), b=17.3382(17), c=15.6687(14) ?, β=110.579(2)o, M_r=731.02, V=3193.9(5) ?~3, Dc=1.520 g/cm~3, Z=4, μ(Mo Kα)=0.833 mm~(-1), F(000)=1508, the final R=0.0431 and w R=0.0936. In the title complex, the central Zn(Ⅱ) ion is located in a distorted octahedral coordination environment. The electrochemical and fluorescent properties were studied. The title complex possesses irreversible electron transfer in the electrode reaction, and it has a strong emission peak in the range of 470~505 nm, with the excitation wavelength being 488 nm.     

Synthesis, Crystal Structure and Thermal Stability of a Saturated Dimeric Ce(Ⅲ)-chelated Complex Based on Benzoate and 1,10-Phenanthroline Ligands

The title complex, [Ce(BA)3phen]2 (BA = benzoate, phen = 1,10-phenanthroline),was prepared by the reaction of Ce(NO3)3·6H2O, benzoic acid and 1,10-phenanthroline. The complex was characterized by single-crystal X-ray diffraction, elemental analysis, IR spectra and TG-DTG techniques. The results show that the crystal is of triclinic, space group P(1) with a =10.912(2), b = 11.962(3), c = 12.474(3)(A), a = 104.889(3), β = 93.523(3), γ = 113.332(3)°,C66H46Ce2N4O12, Mr = 1366.90, V= 1420.2(6) (A)3, Z = 1, Dc = 1.598 g/cm3,μ = 1.652 mm-1, S =1.024 and F(000) = 682. The final R = 0.0391 and wR = 0.0947 for 4878 observed reflections with I ＞ 2σ(1). The structure of the title complex consists of two Ce(C6H5COO)3(C12H8N2) units,forming a binuclear molecule. Each Ce(Ⅲ) is coordinated by two O atoms of one bidentate chelating carboxylate group, five O atoms of two bidentate bridging and two tridentate chelating-bridging carboxylate groups, and two N atoms of one 1,10-phenanthroline molecule to complete a distorted monocapped square antiprism geometry. Its thermogravimetric analysis was determined by TG-DTG techniques.     

Crystal Structure, Nano-particle Morphology and Interaction with ATP of[NH3CH2CH(NH2)CH3]2[M(Ⅵ)O2(OC6H4O)2] (M=Mo0.6W0.4) and Its Activity to Promote DNA Cleavage

The title complex[NH3CH2CH(NH2)CH3]2[M(Ⅵ)O2(OC6H4O)2](M=Mo0.6W0.4)was synthesized via a simple solution-phase chemical route. The determination of single crystal X-ray diffraction revealed that the title compound is crystallized in a monoclinic system with P2(1)/n space group, a=1.0913(10) nm, b=1. 0442(10) nm,c=1.8842(19) nm, α=90°, β=96.530(17)°, γ=90°,Z=4, and V=2. 133(4) nm3. The mononuclear anionic unit [M(Ⅵ)O2(OC6H4O)2]2- displays chiral pseudo-octahedral [MO6] coordination geometry and is ges show that the title complex is comprised of nano-particles with diameters ranging from 20 to 50 nm. The NMR study shows the 1 H downfield chemical shifts of [NH3CHaHbCH(NH2)CH3] cations in the title complex when it is mixed with adenosine-triphosphate(ATP), and the chemical shift difference between Ha and Hb is increased greatly,and most of the catecholate ligands dissociate from the central metal atoms. The DNA cleavage activity experiment reveals that DNA cleavage promoted by the title complex is lower than that by Na2MoO4 which possesses antitumor property, but higher than that by Na2WO4.