新型尼龙214,414,614,814,1014和1214的合成与表征

用熔融缩聚法基于十四碳二酸合成了一系列偶偶尼龙，包括尼龙2 14，4 14， 6 14，8 14，10 14，12 14。用红外光谱、元素分析、核磁共振、差示扫描热分析 、热失重分析、热机械分析、粘度法对合成尼龙的结构与性能进行了表征。同时还 初步研究了尼龙12 14的物理性能，发现其物理性能介于尼龙66和聚乙烯之间。     

Synthesis of 14-deoxy-14α-strophanthidin

Synthesis of the title compound (XVIII) from pregnanolone benzoate (I) is described. Characteristic features of this approach are the protection of the 19-hydroxyl as methyl ether and introduction of the 5β-hydroxyl by hypobromous acid addition with participation of the 19-substituent.     

Die Methanolyseprodukte von 14-Brom-codeinon-dimethylacetal: (14S)-14-Methoxy-codeinon

Zusammenfassung Beim Erhitzen von 14-Brom-codeinon-dimethylacetal (1) in absol. Methanol mit einer äquivalenten Menge Na₂CO₃ entstehen die drei isomeren Methoxycodeinon-acetale3, 4 und5 sowie die beiden Indolino-codeinonderivate6 und7. Die Strukturen und Konfigurationen der Verbindungen3–6 werden auf Grund der NMR- und IR-Spektren sowie durch Umwandlung in bekannte Verbindungen bewiesen.

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The methanolysis of 14-bromo-codeinone dimethyl acetal

14-Bromocodeinone dimethyl acetal (1) reacts in methanol containing sodium carbonate (0.5 moles) to give the three isomeric methoxycodeinone acetals3, 4, and5 besides the indolino-codeinones6 and7. The structures and configurations of3–6 were established on the basis of NMR- and IR-spectroscopy and by conversion to known compounds.

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Herrn Prof.E. Ziegler mit den besten Wünschen zum 60. Geburtstag gewidmet.     

Kohlenstoff 14

Ohne Zusammenfassung     

14-hydroxysteroids

Conclusions Employing a number of chemical transformations, as well as the IR and NMR spectra, we corroborated the anti-cis-configuration for the 3-methyl ether of 14-hydroxy-9(11)-dehydro-8-D-homoestrone, which was proposed previously on the basis of the mass-spectrometric fission data.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 1, pp. 96–100, January, 1973.     

X-ray photoelectron study of relaxation processes in Ni72Mo14B14 and Ni72Nb14B14 melts

The time dependence of the chemical structure of the surface layers of nickel melts is investigated for the first time by X-ray photoelectron spectroscopy. Changes in the chemical structure of amorphous alloys obtained from the same melts are investigated according to depth. Translated fromZhumal Struktumoi Khimii, Vol. 39, No. 6, pp. 1103–1106, November–December, 1998.     

Potential of Si14Ge14 and B14P14 nanocages as electrodes of metal-ion batteries: a theoretical investigation

Journal of Solid State Electrochemistry - In this study, the potential of Si14Ge14 and B14P14 as anode electrodes in metal-ion batteries by using of the density functional theory was investigated....     

Δ<Superscript>8(14)</Superscript>-14α-deoxy- and 14α-deoxy-14α-hydroperoxyecdysteroids

Δ⁸⁽¹⁴⁾-14α-deoxy- and 14α-deoxy-14α-hydroperoxyecdysteroids were synthesized, the reduction of Δ⁸⁽¹⁴⁾-14α-deoxy-20-hydroxyecdysone diacetonide at treatment with complex hydrides of alkali metals was investigated, and the stereochemistry of the obtained 6-hydroxy derivative and its acetate was established.     

Synthesis of 14-Bromo and 14-Hydroxy Baccatin III Derviatives

Numerous efforts towards synthesis of anticancer drug paclitaxel (Taxol(r), 1a) with improved activities led to the modification at 13-phenylisoserine side chain and different positions of its core structure-baccatin III 1c1. At the same time, the activities of searching new taxoids for starting materials of new semi-synthetic paclitaxel analogs from Taxus spp. plant have not ever been stopped. Among these taxoids, 14?-hydroxy-10-deacetylbaccatin III 22 and 13-acetyl-9-dihydrobaccatin III …     

14 verschiedene Arzneimittel

Ohne Zusammenfassung     

METALLOLES-14 CHEMISTRY

Abstract

In order to obtain β-functionalized 1-sila (or germa)-cyclopent-2-enes (M = Si, Ge; R¹, R² = Me or Ph; R³, R⁴ = H or Me) (I) various oxidation methods of metallacyclopent-3-enes have been examinated. The resulting metallacyclopent-4-ene-3-ols (I, X = OH) were converted into phenylcarbamates (I = OC(O)NHPh) or S-methylxanthates (I = OC(S)SMe) and their utility as intermediates in the synthesis of metalloles (siloles and germoles) was investigated.

Depending on the experimental conditions, catalytic dehydration of metallacyclopentenols or thermolysis of carbamates or xanthates give various dienes via four different reaction processes: i) β-elimination C-M; ii) β-elimination C-H; iii) isomerization of C-methylated metalloles; iv) catalytic demetallation.

The thermolysis of arylcarbamates is the best method for conversion of I to metalloles, specially for the synthesis of remarkably dimerization-stable 1,1-R¹R²-3,4-dimethylmetalloles (≥ 80% yield). A one pot synthesis of these stable metalloles from the corresponding alcohol and phenyl isocyanate is proposed.

Unstable monomeric metalloles are stabilized by transition metal complexes or trapped by a (4 + 2) cycloaddition.