Carbonylverbindungen als Kohlenstoffsäuren

Proton transfer to carbon bases (enols) and from carbon acids (ketones) determines the rate of ketonization and enolization reactions, respectively. Kinetic studies performed over the last two decades have provided absolute rate constants and reliable equilibrium constants for a broad range of prototropic reactions. Structure-reactivity and free energy relationships now form a reliable framework to predict the reactivity of the transient species involved in these fundamental reactions. Comparison of reaction rates in aqueous solution with rates achieved by enzymes reveals the striking efficiency of the latter.     

Tetrajodterephtalsäure-derivate als Röntgen-Kontrastmittel

New monoamides and diamides of tetraiodoterephthalic acid have been synthesized for evaluation as X-ray contrast agents. Solubility, toxicity, bilitropism, urotropism, and in some cases cholecystographic quality of these compounds are given.