首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 109 毫秒
1.
An efficient route for the synthesis of novel 7-aryl and 7-spiropyrazolo[4\(^{\prime }\),3\(^{\prime }\):5,6]pyrido[2,3-d]pyrimidine derivatives is described. These compounds were obtained by a cyclocondensation reaction between pyrazolopyridinediamines 4 and aldehydes 5 or cyclic ketones 6 in the presence of acetic acid as catalyst. This procedure provides the desired compounds in good yields under a simple two-step methodology. The obtained compounds were evaluated as AChE inhibitors and showed weak AChe inhibition with \(\hbox {IC}_{50} = 115{-}470 \, \upmu \hbox {M}\).  相似文献   

2.
Spectral dispersions of index of refraction \({n(\lambda )}\) and extinction coefficient \({\kappa (\lambda )}\) of undoped amorphous selenium (a-Se) films of three thicknesses (d?≈?0.5, 0.75, and 1.0 µm) were evaluated by analyzing experimental room-temperature normal-incidence transmittance-wavelength (\({{T_{{\text{exp}}}}(\lambda )} - \lambda\)) data (λ =?400–1100 µm) of their air-supported {a-Se film/thick glass slide}-stacks using Swanepoel’s transmission envelope theory of uniform films. Above a wavelength \({{\lambda _c}\,\, \approx \,\,640\;{\text{nm}}}\), as-measured \({{T_{{\text{exp}}}}(\lambda )}\,\, - \,\lambda\) spectra display well-resolved maxima and minima, with minor shrinkage in transparent and weak absorption regions (750–1100 nm). Below \({\lambda _{\text{c}}}\), a smeared sharp decline of \({{T_{{\text{exp}}}}(\lambda )}\) with decreasing λ, signifying strong absorption in a-Se films and existence of band-tail localized states. For λ > λ c, the \({n\,(\lambda )}\, - \,\lambda\) data retrieved from algebraic envelope procedures followed a Sellmeier-like dispersion relation, with the best-fit values of high-frequency dielectric constant \({{\varepsilon _\infty }\, \approx \,\,{\text{4.9}}}\), static index of refraction \({{n_{\text{0}}} = n\left( {E\, \to \,{\text{0}}} \right)\,\, \approx \,\,{\text{2.43}}}\), and resonance wavelength \({{\lambda _0}\, \approx \,490\,\,{\text{nm}}}\), which may be assigned to onset of photogeneration in a-Se. Urbach-like dependency of absorption coefficient \({\alpha (h{{\nu }})}\) of a-Se films on photon energy \({h{{\nu }}}\) was realized with an Urbach-tail breadth of 85 meV. All achieved optical parameters were found to be slightly dependent on film thickness. Findings of present algebraic analysis are consistent with reported literature results obtained on the basis of other optical analytical approaches.  相似文献   

3.
The K--induced production of \( \Lambda\)(1405) is investigated in K - d \( \rightarrow\) \( \pi\) \( \Sigma\) n reactions based on coupled-channels chiral dynamics, in order to discuss the resonance position of the \( \Lambda\)(1405) in the \( \bar{{K}}\) N channel. We find that the K - d \( \rightarrow\) \( \Lambda\)(1405)n process favors the production of \( \Lambda\)(1405) initiated by the \( \bar{{K}}\) N channel. The present approach indicates that the \( \Lambda\)(1405) -resonance position is 1420MeV rather than 1405MeV in the \( \pi\) \( \Sigma\) invariant-mass spectra of K - d \( \rightarrow\) \( \pi\) \( \Sigma\) n reactions. This is consistent with an observed spectrum of the K - d \( \rightarrow\) \( \pi^{{+}}_{}\) \( \Sigma^{{-}}_{}\) n with 686-844MeV/c incident K- by bubble chamber experiments done in the 70s. Our model also reproduces the measured \( \Lambda\)(1405) production cross-section.  相似文献   

4.
Let G n ? Diff+(S 1) be the stabilizer of n given points of S 1. How much information do we lose if we restrict a positive energy representation \(U^c_h\) associated to an admissible pair (c, h) of the central charge and lowest energy, to the subgroup G n ? The question, and a part of the answer originate in chiral conformal QFT. The value of c can be easily “recovered” from such a restriction; the hard question concerns the value of h. If c ≤ 1, then there is no loss of information, and accordingly, all of these restrictions are irreducible. In this work it is shown that \(U^c_{h}|_{G_n}\) is always irreducible for n =  1 and, if h =  0, it is irreducible at least up to n ≤  3. Moreover, an example is given for c >  2 and certain values of \(h \neq \tilde{h}\) such that \(U^c_{h}|_{G_1}\simeq U^c_{\tilde{h}}|_{G_1}\) . It is also concluded that for these values \(U^c_{h}|_{G_n}\) cannot be irreducible for n ≥  2. For further values of c, h and n, the question is left open. Nevertheless, the example already shows that, on the circle, there are conformal QFT models in which local and global intertwiners are not equivalent.  相似文献   

5.
We consider bond percolation on \({\mathbb {Z}}^d\times {\mathbb {Z}}^s\) where edges of \({\mathbb {Z}}^d\) are open with probability \(p<p_c({\mathbb {Z}}^d)\) and edges of \({\mathbb {Z}}^s\) are open with probability q, independently of all others. We obtain bounds for the critical curve in (pq), with p close to the critical threshold \(p_c({\mathbb {Z}}^d)\). The results are related to the so-called dimensional crossover from \({\mathbb {Z}}^d\) to \({\mathbb {Z}}^{d+s}\).  相似文献   

6.
Let {M k } be a degenerating sequence of finite volume, hyperbolic manifolds of dimension d, with d = 2 or d = 3, with finite volume limit M . Let \({Z_{M_{k}} (s)}\) be the associated sequence of Selberg zeta functions, and let \({{\mathcal{Z}}_{k} (s)}\) be the product of local factors in the Euler product expansion of \({Z_{M_{k}} (s)}\) corresponding to the pinching geodesics on M k . The main result in this article is to prove that \({Z_{M_{k}} (s)/{\mathcal{Z}}_{k} (s)}\) converges to \({Z_{M_{\infty}} (s)}\) for all \({s \in \mathbf{C}}\)with Re(s) > (d ? 1)/2. The significant feature of our analysis is that the convergence of \({Z_{M_{k}} (s)/{\mathcal{Z}}_{k} (s)}\) to \({Z_{M_{\infty}} (s)}\) is obtained up to the critical line, including the right half of the critical strip, a region where the Euler product definition of the Selberg zeta function does not converge. In the case d = 2, our result reproves by different means the main theorem in Schulze (J Funct Anal 236:120–160, 2006).  相似文献   

7.
Let μ be an arbitrary composition of M + N and let \({\mathfrak{s}}\) be an arbitrary \({0^{M}1^{N}}\)- sequence. A new presentation, depending on \({\mu \rm and \mathfrak{s}}\), of the super Yangian YM|N associated to the general linear Lie superalgebra \({\mathfrak{gl}_{M|N}}\) is obtained.  相似文献   

8.
In the structure-dynamic approach of nanoionics, the method of a uniform effective field \( {F}_{\mathrm{eff}}^{j,k} \) of a crystallographic planeX j has been substantiated for solid electrolyte nanostructures. The \( {F}_{\mathrm{eff}}^{j,k} \)is defined as an approximation of a non-uniform field \( {F}_{\mathrm{dis}}^j \)of X j with a discrete- random distribution of excess point charges. The parameters of \( {F}_{\mathrm{eff}}^{j,k} \)are calculated by correction of the uniform Gauss field \( {F}_{\mathrm{G}}^j \) of X j . The change in an average frequency of ionic jumps X k ?→?X k?+?1 between adjacent planes of nanostructure is determined by the sum of field additives to the barrier heights η k , k?+?1, and for \( {F}_{\mathrm{G}}^j \) and \( {F}_{\mathrm{dis}}^j \), these sums are the same decimal order of magnitude. For nanostructures with length ~4 nm, the application of \( {F}_{\mathrm{G}}^j \) (as \( {F}_{\mathrm{eff}}^{j,k} \)) gives the accuracy ~20 % in calculations of ion transport characteristics. The computer explorations of the “universal” dynamic response (Reσ ??∝?ω n ) show an approximately the same power n < ≈1 for\( {F}_{\mathrm{G}}^j \) and \( {F}_{\mathrm{eff}}^{j,k} \).  相似文献   

9.
The hyperfine constants of the levels 2p 2 \((^{3}\)P)3s 4P J , 2p 2 \((^3\)P)3p 4P\(^o_J\) and 2p 2 \((^3\)P)3p 4D\(^o_J\), deduced by Jennerich et al. [Eur. Phys. J. D 40, 81 (2006)] from the observed hyperfine structures of the transitions 2p 2 \((^3\)P)3s 4P J \(\rightarrow\) 2p 2 \((^3\)P)3p 4P\(^o_{J'}\) and 2p 2 \((^3\)P)3s 4P J \(\rightarrow\) 2p 2 \((^3\)P)3p 4D\(^o_{J'}\) recorded by saturation spectroscopy in the near-infrared,strongly disagree with the ab initio values of Jönsson et al. [J. Phys. B: At. Mol.Opt. Phys. 43, 115006 (2010)].We propose a new interpretation of the recorded weak spectral lines. If the latter are indeed reinterpreted as crossover signals, a new set of experimental hyperfine constants is deduced, in very good agreement with the ab initio predictions.  相似文献   

10.
Let \({T=\mathbb R^d}\) . Let a function \({QT^2\to\mathbb C}\) satisfy \({Q(s,t)=\overline{Q(t,s)}}\) and \({|Q(s,t)|=1}\). A generalized statistics is described by creation operators \({\partial_t^\dagger}\) and annihilation operators ? t , \({t\in T}\), which satisfy the Q-commutation relations: \({\partial_s\partial^\dagger_t = Q(s, t)\partial^\dagger_t\partial_s+\delta(s, t)}\) , \({\partial_s\partial_t = Q(t, s)\partial_t\partial_s}\), \({\partial^\dagger_s\partial^\dagger_t = Q(t, s)\partial^\dagger_t\partial^\dagger_s}\). From the point of view of physics, the most important case of a generalized statistics is the anyon statistics, for which Q(s, t) is equal to q if s < t, and to \({\bar q}\) if s > t. Here \({q\in\mathbb C}\) , |q| = 1. We start the paper with a detailed discussion of a Q-Fock space and operators \({(\partial_t^\dagger,\partial_t)_{t\in T}}\) in it, which satisfy the Q-commutation relations. Next, we consider a noncommutative stochastic process (white noise) \({\omega(t)=\partial_t^\dagger+\partial_t+\lambda\partial_t^\dagger\partial_t}\) , \({t\in T}\) . Here \({\lambda\in\mathbb R}\) is a fixed parameter. The case λ = 0 corresponds to a Q-analog of Brownian motion, while λ ≠ 0 corresponds to a (centered) Q-Poisson process. We study Q-Hermite (Q-Charlier respectively) polynomials of infinitely many noncommutatative variables \({(\omega(t))_{t\in T}}\) . The main aim of the paper is to explain the notion of independence for a generalized statistics, and to derive corresponding Lévy processes. To this end, we recursively define Q-cumulants of a field \({(\xi(t))_{t\in T}}\). This allows us to define a Q-Lévy process as a field \({(\xi(t))_{t\in T}}\) whose values at different points of T are Q-independent and which possesses a stationarity of increments (in a certain sense). We present an explicit construction of a Q-Lévy process, and derive a Nualart–Schoutens-type chaotic decomposition for such a process.  相似文献   

11.
A library of hybrid molecules bearing thioglycoluril and (hetero)aromatic aldehyde thiosemicarbazone moieties was synthesized via a tandem hydrazone formation—ring contraction reaction of 5,7-dialkyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-ones with (hetero)aromatic aldehydes. All synthesized compounds were tested for their cytotoxic activity against rhabdomyosarcoma, A549, and MS human cancer cell lines by MTT-assay. Among the derivatives, (E)-4-benzylideneamino-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one 1f was found to have the most marked antiproliferative activity toward the tested cell lines (1f: IC\(_{50}= 20.6,\) 23.7, and 6.4 \(\upmu \)M, respectively). The IC\(_{50}\) value of thioglycoluril 1f against normal human embryonic kidney cells HEK293 was 72.5 \(\upmu \)M, which appeared to be 3–11-fold higher than IC\(_{50}\) values of 1f against human cancer cells.  相似文献   

12.
Photoreflectance spectra have been measured on the chalcopyrite semiconductor silver indium disulfide (\(\hbox {AgInS}_{2}\)) for light polarization \({\varvec{E}}\) perpendicular (\({\varvec{E}} \bot {c}\)) and parallel to the c-axis (\({\varvec{E}} \vert \vert {c}\)) at temperature between 10 and 300 K. The measured photoreflectance spectra revealed distinct structures at 1.8–2.1 eV. The lowest bandgap energies \(E_{0A}\), \(E_{0B}\), and \(E_{0C}\) of \(\hbox {AgInS}_{2}\) show unusual temperature dependence at low temperatures (\(\le\)140 K). The \(E_{0\alpha }\) (\(\alpha =A, B, C\)) is found to increase with increasing temperature from 10 to \(\sim\)140 K and decreases with a further increase in temperature. This result has been successfully explained by taking into account the effects of thermal expansion and electron–phonon interaction. The spin–orbit and crystal-field splitting parameters of \(\hbox {AgInS}_{2}\) are determined to be \(\Delta _{{\mathrm{so}}}=38\) meV and \(\Delta _{{\mathrm{cr}}}=-168\) meV at T = 10 K, respectively, and are discussed from an aspect of the electronic energy band structure consequences. The temperature dependence of spin–orbit and crystal-field splitting parameters of \(\hbox {AgInS}_{2}\) was also presented.  相似文献   

13.
A series of amino-substituted \(\alpha \)-cyanostilbene derivatives and their bile acid (cholic and deoxycholic acid) amides were designed and synthesized. A comparative study on the anticancer and antibacterial activity evaluation on the synthesized analogs was carried against the human osteosarcoma (HOS) cancer cell line, and two gram ?ve (E. coli and S. typhi) and two gram \(+\)ve (B. subtilis and S. aureus) bacterial strains. All the cholic acid \(\alpha \)-cyanostilbene amides showed an \(\hbox {IC}_{50}\) in the range 2–13 \(\upmu \hbox {M}\) against human osteosarcoma cells (HOS) with the most active analog (6g) possessing an \(\hbox {IC}_{50}\) of \(2\,\upmu \hbox {M}\). One of the amino-substituted \(\alpha \)-cyanostilbene, 4e, was found to possess an \(\hbox {IC}_{50}\) of \(3\,\upmu \hbox {M}\). An increase in the number of cells at the sub-\(\hbox {G}_{1}\) phase of the cell was observed in the in vitro cell cycle analysis of two most active compounds in the series (4e, 6g) suggesting a clear indication toward induction of apoptotic cascade. With respect to antibacterial screening, amino-substituted \(\alpha \)-cyanostilbenes were found to be more active than their corresponding bile acid amides. The synthesized compounds were also subjected to in silico study to predict their physiochemical properties and drug-likeness score.  相似文献   

14.
For the Ising model (with interaction constant J>0) on the Cayley tree of order k≥2 it is known that for the temperature TT c,k =J/arctan?(1/k) the limiting Gibbs measure is unique, and for T<T c,k there are uncountably many extreme Gibbs measures. In the Letter we show that if \(T\in(T_{c,\sqrt{k}}, T_{c,k_{0}})\), with \(\sqrt{k} then there is a new uncountable set \({\mathcal{G}}_{k,k_{0}}\) of Gibbs measures. Moreover \({\mathcal{G}}_{k,k_{0}}\ne {\mathcal{G}}_{k,k'_{0}}\), for k 0k0. Therefore if \(T\in (T_{c,\sqrt{k}}, T_{c,\sqrt{k}+1})\), \(T_{c,\sqrt{k}+1} then the set of limiting Gibbs measures of the Ising model contains the set {known Gibbs measures}\(\cup(\bigcup_{k_{0}:\sqrt{k}.  相似文献   

15.
We consider two ensembles of \(0-1\) \(n\times n\) matrices. The first is the set of all \(n\times n\) matrices with entries zeroes and ones such that all column sums and all row sums equal r, uniformly weighted. The second is the set of \(n \times n\) matrices with zero and one entries where the probability that any given entry is one is r / n, the probabilities of the set of individual entries being i.i.d.’s. Calling the two expectation values E and \(E_B\) respectively, we develop a formal relation
$$\begin{aligned} E({{\mathrm{perm}}}(A)) = E_B({{\mathrm{perm}}}(A)) e^{\sum _2 T_i}.\quad \quad \quad \quad \mathrm{(A1)} \end{aligned}$$
We use two well-known approximating ensembles to E, \(E_1\) and \(E_2\). Replacing E by either \(E_1\) or \(E_2\) we can evaluate all terms in (A1). For either \(E_1\) or \(E_2\) the terms \(T_i\) have amazing properties. We conjecture that all these properties hold also for E. We carry through a similar development treating \(E({{\mathrm{perm}}}_m(A))\), with m proportional to n, in place of \(E({{\mathrm{perm}}}(A))\).
  相似文献   

16.
A multiparametric family of 2D Toda \({\tau}\) -functions of hypergeometric type is shown to provide generating functions for composite, signed Hurwitz numbers that enumerate certain classes of branched coverings of the Riemann sphere and paths in the Cayley graph of S n . The coefficients \({{F^{c_{1}, . . . , c_{l}}_{d_{1}, . . . , d_{m}}}(\mu, \nu)}\) in their series expansion over products \({P_{\mu}P^{'}_{\nu}}\) of power sum symmetric functions in the two sets of Toda flow parameters and powers of the l + m auxiliary parameters are shown to enumerate \({|\mu|=|\nu|=n}\) fold branched covers of the Riemann sphere with specified ramification profiles \({ \mu}\) and \({\nu}\) at a pair of points, and two sets of additional branch points, satisfying certain additional conditions on their ramification profile lengths. The first group consists of l branch points, with ramification profile lengths fixed to be the numbers \({(n-c_{1}, . . . , n-c_{l})}\) ; the second consists of m further groups of “coloured” branch points, of variable number, for which the sums of the complements of the ramification profile lengths within the groups are fixed to equal the numbers \({(d_{1}, . . . , d_{m})}\). The latter are counted with signs determined by the parity of the total number of such branch points. The coefficients \({{F^{c_{1}, . . . , c_{l}}_{d_{1}, . . . , d_{m}}}(\mu, \nu)}\) are also shown to enumerate paths in the Cayley graph of the symmetric group S n generated by transpositions, starting, as in the usual double Hurwitz case, at an element in the conjugacy class of cycle type \({\mu}\) and ending in the class of type \({\nu}\), with the first l consecutive subsequences of \({(c_{1}, . . . , c_{l})}\) transpositions strictly monotonically increasing, and the subsequent subsequences of \({(d_{1}, . . . , d_{m})}\) transpositions weakly increasing.  相似文献   

17.
Treating the light-flavor constituent quarks and antiquarks whose momentum information is extracted from the data of soft light-flavor hadrons in pp collisions at \(\sqrt{s}=7\) TeV as the underlying source of chromatically neutralizing the charm quarks of low transverse momenta (\(p_{T}\)), we show that the experimental data of \(p_{T}\) spectra of single-charm hadrons \(D^{0,+}\), \(D^{*+}\) \(D_{s}^{+}\), \(\varLambda _{c}^{+}\) and \(\varXi _{c}^{0}\) at mid-rapidity in the low \(p_{T}\) range (\(2\lesssim p_{T}\lesssim 7\) GeV/c) in pp collisions at \(\sqrt{s}=7\) TeV can be well understood by the equal-velocity combination of perturbatively created charm quarks and those light-flavor constituent quarks and antiquarks. This suggests a possible new scenario of low \(p_{T}\) charm quark hadronization, in contrast to the traditional fragmentation mechanism, in pp collisions at LHC energies. This is also another support for the exhibition of the soft constituent quark degrees of freedom for the small parton system created in pp collisions at LHC energies.  相似文献   

18.
In this article, we construct the \(C \otimes \gamma _\mu C\) and \(C\gamma _5 \otimes \gamma _5\gamma _\mu C\) type currents to interpolate the vector tetraquark states, then carry out the operator product expansion up to the vacuum condensates of dimension-10 in a consistent way, and obtain four QCD sum rules. In calculations, we use the formula \(\mu =\sqrt{M^2_{Y}-(2{\mathbb {M}}_c)^2}\) to determine the optimal energy scales of the QCD spectral densities, moreover, we take the experimental values of the masses of the Y(4260 / 4220), Y(4360 / 4320), Y(4390) and Y(4660 / 4630) as input parameters and fit the pole residues to reproduce the correlation functions at the QCD side. The numerical results support assigning the Y(4660 / 4630) to be the \(C \otimes \gamma _\mu C\) type vector tetraquark state \(c\bar{c}s\bar{s}\), assigning the Y(4360 / 4320) to be \(C\gamma _5 \otimes \gamma _5\gamma _\mu C\) type vector tetraquark state \(c\bar{c}q\bar{q}\), and disfavor assigning the Y(4260 / 4220) and Y(4390) to be the pure vector tetraquark states.  相似文献   

19.
Let \({\mathfrak{D}}\) be the space consists of pairs (f, g), where f is a univalent function on the unit disc with f(0) = 0, g is a univalent function on the exterior of the unit disc with g(∞) = ∞ and f′(0)g′(∞) = 1. In this article, we define the time variables \({t_n, n\in \mathbb{Z}}\), on \({\mathfrak{D}}\) which are holomorphic with respect to the natural complex structure on \({\mathfrak{D}}\) and can serve as local complex coordinates for \({\mathfrak{D}}\) . We show that the evolutions of the pair (f, g) with respect to these time coordinates are governed by the dispersionless Toda hierarchy flows. An explicit tau function is constructed for the dispersionless Toda hierarchy. By restricting \({\mathfrak{D}}\) to the subspace Σ consists of pairs where \({f(w)=1/\overline{g(1/\bar{w})}}\), we obtain the integrable hierarchy of conformal mappings considered by Wiegmann and Zabrodin [31]. Since every C 1 homeomorphism γ of the unit circle corresponds uniquely to an element (f, g) of \({\mathfrak{D}}\) under the conformal welding \({\gamma=g^{-1}\circ f}\), the space Homeo C (S 1) can be naturally identified as a subspace of \({\mathfrak{D}}\) characterized by f(S 1) = g(S 1). We show that we can naturally define complexified vector fields \({\partial_n, n\in \mathbb{Z}}\) on Homeo C (S 1) so that the evolutions of (f, g) on Homeo C (S 1) with respect to ? n satisfy the dispersionless Toda hierarchy. Finally, we show that there is a similar integrable structure for the Riemann mappings (f ?1g ?1). Moreover, in the latter case, the time variables are Fourier coefficients of γ and 1/γ ?1.  相似文献   

20.
Contrary to the reaction \( \bar{{p}}\) p \( \rightarrow\) e + e - with a high-momentum incident antiproton on a free target proton at rest, in which the invariant mass M of the e + e - pair is necessarily much larger than the \( \bar{{p}}\) p mass 2m , in the reaction \( \bar{{p}}\) d \( \rightarrow\) e + e - n the value of M can take values near or below the \( \bar{{p}}\) p mass. In the antiproton-deuteron electromagnetic annihilation, this allows to access the proton electromagnetic form factors in the timelike region of q2 near the \( \bar{{p}}\) p threshold. We estimate the cross-section \(d\sigma _{\bar pd \to e^ + e^ - n} /d\mathcal{M}\) for an antiproton beam momentum of 1.5GeV/c. We find that near the \( \bar{{p}}\) p threshold this cross-section is about 1pb/MeV. The case of heavy-nuclei target is also discussed. Elements of experimental feasibility are presented for the process \( \bar{{p}}\) d \( \rightarrow\) e + e - n in the context of the \( \overline{{{\rm P}}}\) ANDA project.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号