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1.
In this paper, we propose and analyze a tuberculosis (TB) model with exogenous re-infection. We assume that treated individual may be again infected by infectious individual. The model exhibits two bifurcations viz. transcritical bifurcation when the basic reproductive number R 0?=?1 and backward bifurcation where the disease transmission rate β plays as control parameter. The persistent of the model and, the local and global stability criteria of disease-free and endemic equilibria are discussed. By carrying out bifurcation analysis, it is shown that the model exhibits the bistability and undergoes the Hopf bifurcation when immunological memory is everlasting i.e. when σ?=?0. Lastly, some simulations are given to verify our analytical results.  相似文献   

2.
This paper considers an epidemic model of a vector-borne disease which has direct mode of transmission in addition to the vector-mediated transmission. The incidence term is assumed to be of the bilinear mass-action form. We include both a baseline ODE version of the model, and, a differential-delay model with a discrete time delay. The ODE model shows that the dynamics is completely determined by the basic reproduction number R0. If R0?1, the disease-free equilibrium is globally stable and the disease dies out. If R0>1, a unique endemic equilibrium exists and is locally asymptotically stable in the interior of the feasible region. The delay in the differential-delay model accounts for the incubation time the vectors need to become infectious. We study the effect of that delay on the stability of the equilibria. We show that the introduction of a time delay in the host-to-vector transmission term can destabilize the system and periodic solutions can arise through Hopf bifurcation.  相似文献   

3.
The global dynamics of an SIRS model with a nonlinear incidence rate is investigated. We establish a threshold for a disease to be extinct or endemic, analyze the existence and asymptotic stability of equilibria, and verify the existence of bistable states, i.e., a stable disease free equilibrium and a stable endemic equilibrium or a stable limit cycle. In particular, we find that the model admits stability switches as a parameter changes. We also investigate the backward bifurcation, the Hopf bifurcation and Bogdanov–Takens bifurcation and obtain the Hopf bifurcation criteria and Bogdanov–Takens bifurcation curves, which are important for making strategies for controlling a disease.  相似文献   

4.
Dynamical behavior of computer virus on Internet   总被引:2,自引:0,他引:2  
In this paper, we presented a computer virus model using an SIRS model and the threshold value R0 determining whether the disease dies out is obtained. If R0 is less than one, the disease-free equilibrium is globally asymptotically stable. By using the time delay as a bifurcation parameter, the local stability and Hopf bifurcation for the endemic state is investigated. Numerical results demonstrate that the system has periodic solution when time delay is larger than a critical values. The obtained results may provide some new insight to prevent the computer virus.  相似文献   

5.
The global dynamics of an SIRS model with a nonlinear incidence rate is investigated. We establish a threshold for a disease to be extinct or endemic, analyze the existence and asymptotic stability of equilibria, and verify the existence of bistable states, i.e., a stable disease free equilibrium and a stable endemic equilibrium or a stable limit cycle. In particular, we find that the model admits stability switches as a parameter changes. We also investigate the backward bifurcation, the Hopf bifurcation and Bogdanov–Takens bifurcation and obtain the Hopf bifurcation criteria and Bogdanov–Takens bifurcation curves, which are important for making strategies for controlling a disease.  相似文献   

6.
We extend a previous Gause-type predator–prey model to include a general monotonic and bounded seasonally varying functional response. The model exhibits rich dynamical behaviour not encountered when the functional response is not seasonally forced. A theoretical analysis is performed on the model to investigate the global stability of the boundary equilibria and the existence of periodic solutions. It is shown that, under certain well-defined conditions, the Poincaré map of the model undergoes a Hopf bifurcation leading to the appearance of a quasi-periodic solution. Numerical results are given for the Poincaré sections and bifurcation diagrams for Holling-types II and III functional responses, using the amplitude of seasonal variation as bifurcation parameter. The model shows a rich variety of behaviour, including period doubling, quasi-periodicity, chaos, transient chaos, and windows of periodicity.  相似文献   

7.
In this paper, we study the dynamics of a mathematical model on primary and secondary cytotoxic T-lymphocyte (CTL) response to viral infections by Wodarz et al. This model has three equilibria and their stability criteria are discussed. The system transitions from one equilibrium to the next as the basic reproductive number, R0, increases. When R0 increases even further, we analytically show that periodic solutions may arise from the third equilibrium via Hopf bifurcation. Numerical simulations of the model agree with the theoretical results and these dynamics occur within biologically realistic parameter range. The normal form theory is also applied to find the amplitude, phase and stability information on the limit cycles. Biological implications of the results are discussed.  相似文献   

8.
In this paper, we propose a delayed computer virus propagation model and study its dynamic behaviors. First, we give the threshold value R0 determining whether the virus dies out completely. Second, we study the local asymptotic stability of the equilibria of this model and it is found that, depending on the time delays, a Hopf bifurcation may occur in the model. Next, we prove that, if R0 = 1, the virus-free equilibrium is globally attractive; and when R0 < 1, it is globally asymptotically stable. Finally, a sufficient criterion for the global stability of the virus equilibrium is obtained.  相似文献   

9.
We formulated and studied a predator–prey system with migrating prey and disease infection in both species. We used Lotka–Volterra type functional response. Mathematically, we analyzed the dynamics of the system such as existence of non negative equilibria, their stability. The basic reproduction number R0 for the proposed mathematical model is calculated. Disease is endemic if R0 > 1. Model is simulated by assuming hypothetical initial values and parameters.  相似文献   

10.
In this paper a mathematical model of AIDS is investigated. The conditions of the existence of equilibria and local stability of equilibria are given. The existences of transcritical bifurcation and Hopf bifurcation are also considered, in particular, the conditions for the existence of Hopf bifurcation can be given in terms of the coefficients of the characteristic equation. The method extends the application of the Hopf bifurcation theorem to higher differential equations which occur in biological models, chemical models, and epidemiological models etc.This project is supported by the National Science Foundation Tian Yuan Terms and LNM Institute of Mechanics Academy of Science.This project is supported by the National and Yunnan Province Natural Science Foundation of China.  相似文献   

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