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1.
Siva S. Panda 《合成通讯》2013,43(5):729-735
A simple and efficient procedure for the synthesis of 2-arylbenzimidazoles through a one-pot condensation of o-phenylenediamines with aryl aldehydes in water is described. Short reaction time, large-scale synthesis, easy and quick isolation of the product, and excellent yield are the main advantages of this procedure. 相似文献
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FeCl3-doped polyaniline nanoparticles efficiently catalyze the synthesis of 2-substituted benzimidazoles by the reaction of aldehydes with o-phenylenediamine. Synthesis and characterization of the catalyst are described, and the obtained results confirms good dispersion of the FeCl3 on the polyaniline. Simple workup, mild reaction conditions, low cost, easy separation, and reusability of the catalyst are some advantages of this method. 相似文献
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I. V. Magedov S. A. Maklakov Yu. I. Smushkevich 《Chemistry of Heterocyclic Compounds》2005,41(4):449-451
A new procedure has been developed for the synthesis of indomethacin by the Fischer reaction, based on the acylation of sodium 2-(4-methoxyphenyl)-1-hydrazosulfonate with 4-chlorobenzoyl chloride and subsequent interaction with levulinic acid in the presence of formic acid.__________Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 530–532, April, 2005. 相似文献
4.
An Unexpected Role of Carbon Disulfide: A New and Efficient Method for the Synthesis of 2‐Substituted Benzimidazoles 下载免费PDF全文
A new and efficient methodology for the synthesis of 2‐substituted benzimidazoles is described. In this procedure, CS2 unexpectedly facilitated the cyclization reaction between benzene‐1,2‐diamine and benzenecarbaldehydes in CH2Cl2 at room temperature. The reactions occur under mild conditions require simpler equipment and easier workup procedures. 相似文献
5.
新型席夫碱大环化合物的合成 总被引:5,自引:0,他引:5
利用Mn2+, Ba2+作为模板离子, 由邻苯二胺和α,ω-二(3'-羟基-4'-甲酰苯氧基)取代烷[即1,4-二(3'-羟基-4'-甲酰苯氧基)丁烷、1,6-二(3'-羟基-4'-甲酰苯氧基)己烷、1,8-二(3'-羟基-4'-甲酰苯氧基)辛烷]反应分别合成了系列新型大环席夫碱化合物Ln (n=4, 6, 8). Mn2+用于L4合成, 并在洗涤时自动解络; L6和L8的合成以Ba2+模板, L6和L8的Ba2+配合物经与Na2SO4水溶液反应解络, 得到自由大环配体L6和L8. 上述新型大环席夫碱化合物采用元素分析, 1H NMR, IR, 紫外-可见光谱和MS等进行组成和结构表征. 相似文献
6.
Jelem Restrepo José Salazar Simón E. López 《Phosphorus, sulfur, and silicon and the related elements》2013,188(12):2311-2320
Abstract We describe a rapid and convenient methodology for the preparation of diverse 3-aryl and 3-trifluoromethyl 4H-1,2,4-benzothiadiazine-1,1-dioxides in a one-pot microwave-promoted reaction between 2-aminobenzenesulfonamides and benzaldehydes, trifluoroacetic acid or benzoic acids. GRAPHICAL ABSTRACT 相似文献
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5‐Amino‐3,4‐diphenylthieno[2,3‐c]pyridazine‐6‐carbonitrile 2a was reacted with propylene diamine to give tetrahydropyrimidinyl derivative 3 . The latter compound ( 3 ) underwent certain cyclocondensation reactions to produce pyrimidothienopyridazines 4–6 . Also, the reactions of 5‐amino‐3,4‐diphenylthieno[2,3‐c]pyridazine‐6‐carboxamide with heterocyclic aldehydes and/or cycloalkanones were carried out and their products were identified. Moreover, some novel pyridazinothienopyrimidobenzimidazoles 14–17 were synthesized. 相似文献
9.
Ali Reza Kiasat Foad Kazemi Froogh Khosravian 《Phosphorus, sulfur, and silicon and the related elements》2013,188(2):427-431
Alcohols are easily converted to their corresponding dialkyl sulfite under mild reaction conditions using Na2SO3/SOCl2 in moderate to good isolated yields. 相似文献
10.
Asymmetric Synthesis of Allylic Sulfonic Acids: Enantio‐ and Regioselective Iridium‐Catalyzed Allylations of Na2SO3 下载免费PDF全文
Wei Liu Prof. Dr. Xiao‐ming Zhao Hong‐bo Zhang Liang Zhang Ming‐zhu Zhao 《Chemistry (Weinheim an der Bergstrasse, Germany)》2014,20(51):16873-16876
An enantioselective allylation reaction of allylic carbonates with sodium sulfite (Na2SO3) catalyzed by Ir complex was accomplished, providing allylic sulfonic acids in good to excellent yields with a high level of enantio‐ and regioselectivities. (R)‐2‐Phenyl‐2‐sulfoacetic acid, a key intermediate for the synthesis of Cefsulodin and Sulbenicillin, was synthesized as well. 相似文献
11.
Khalid Mohammed Khan Ghulam Murtaza MaharviSafdar Hayat Zia-UllahM. Iqbal Choudhary Atta-ur-Rahman 《Tetrahedron》2003,59(29):5549-5554
Treatment of aromatic carboxylic acids and substituted toluenes with a mixture of sodium bromate and sodium hydrogen sulfite in a two-phase system gave the corresponding esters in good yield. The intermediate α-brominated toluene was formed by the in situ generated hypobromous acid. The α-bromotoluene underwent an intermolecular nucleophilic substitution reaction with aromatic carboxylic acids present in the reaction mixture to afford the corresponding esters. 相似文献
12.
Russavskaya N. V. Korchevin N. A. Alekminskaya O. V. Sukhomazova E. N. Levanova E. P. Deryagina E. N. 《Russian Journal of Organic Chemistry》2002,38(10):1445-1448
Reaction of thiols with dihaloalkanes in the system hydrazine hydrate-base leads to alkyl(chloroalkyl) sulfides with different positions of the chlorine atom with respect to sulfur. The developed one-step procedure for the synthesis of such unsymmetrical sulfides is most suitable for arenethiols and alkanethiols having a long polymethylene chain. The reaction mechanism is discussed. 相似文献
13.
A simple approach to preparation of benzimidazoles from o-phenylenediamines and DMF derivatives, only employing PhSiH3 as promoter without any other additives, was reported. This route provided moderate to high yields with a broad substrate scope. A plausible mechanism for the reaction is proposed based on the spectroscopic characterization (e.g., HRMS and 1H NMR) of the reaction mixture. 相似文献
14.
A novel and efficient route has been developed for the synthesis of benzimidazole derivatives via ligand-free CuBr-catalyzed oxidation and cyclization of 1,2-diamines derived from 1-fluoro-2-nitrobenzene and different arylamines as starting materials. 相似文献
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Kryukov A. I. Zin'chuk N. N. Korzhak A. V. Kuchmii S. Ya. 《Theoretical and Experimental Chemistry》2003,39(1):9-14
The formation of nanoparticles of metallic silver in the reduction of Ag+ ions catalyzed by colloidal Ag2S was investigated. It was established that the position of the surface plasmon resonance bands of the Ag nanoparticles is affected by the concentration of the catalyst, its particle size and the amount of particles with the same size, the stabilization conditions, the concentration of Ag+ ions, and the temperature at which the process is conducted. An explanation for the spectral changes that occur is proposed. 相似文献
17.
合成有机锗倍半硫化物的新方法 总被引:5,自引:0,他引:5
有机锗倍半硫化物的合成是有机锗抗癌药物研究中的热点之一。在路易斯碱(如吡啶或三乙胺)存在下,经有机锗三氯化物溶液中通干燥的硫化氢气体制得有机锗倍半硫化物的方法有许多缺点,如无法计算吸收的硫化氢的量、设备复杂、操作困难并产生硫化氢臭味和毒性。我们用无水硫化钠直接与有机锗三氯化物作用即可得到有机锗倍半硫化物。利用此法合成了8种有机锗倍半硫化物: 相似文献
18.
ZHENG Zhan-Ying SONG Hai-Bin TONG Jun YAN Dong-Wen LI Zheng-Ming CHEN Jian-Yu ZHANG Shu-Jun LIU Xing-Hai WANG Su-Hua 《结构化学》2008,27(7)
Monosulfuron is a novel sulfonylurea herbicide with ultra-low dosage invented and patented by Nankai University.Herein its sodium salt was firstly synthesized and crystal structure was determined by X-ray diffraction method.The title compound belongs to the triclinic system, space group P1- with a = 7.306(6), b = 9.446(8), c = 11.872(10)(A), α= 76.578(14), β= 78.049(13), γ= 77.620(14)°, V = 767.7(11)(A)3, Mr = 377.32, Z = 2, Dc = 1.632 g/cm3,μ= 0.283 mm-1, F(000) = 388, R = 0.0444 and wR = 0.1186.In the title compound, Na(1) coordinates with O(4) and O(5) from one monosulfuron molecule, N(4A) and O(5A) from the other monosulfuron molecule and the oxygen atom from H2O to give five coordination bonds.The title complex is further linked into a three-dimensional structure through π…π interactions and intermolecular hydrogen bonds between the oxygen and nitrogen atoms. 相似文献
19.
2,2-Dimethyl-4-methoxychromans (1–12) have been converted into 2,2-dimethyl-2H-chromenes (13–24) in acidic media. 相似文献
20.
碘促进的苯并咪唑及其衍生物的合成 总被引:3,自引:0,他引:3
在碘的氧化作用下,由伯醇和邻苯二胺一步合成了苯并咪唑及其衍生物。考察了碘和碳酸钾用量及温度对反应产率的影响,反应较佳的条件为n(o-ClC6H4CH2OH)∶n(o-phenylenediamine)∶n(I2)∶n(K2CO3)=1.0∶1.1∶5.0∶5.0,反应温度70℃,反应时间5 h。用方法A在较佳的反应条件下2-(2-氯苯基)苯并咪唑的产率可达86%,用方法B其产率达69%。没有选择传统的醛或酸作为反应底物,而是选择了伯醇在碘的氧化作用下直接合成了目标产物,反应为合成苯并咪唑及其衍生物的一个新方法,探讨了可能的反应机理。 相似文献