A novel and facile synthesis of N-cyclohexyl-benzofurans by one-pot three-component reaction

Abstract  

A simple and efficient synthesis of N-cyclohexyl-benzofuran derivatives was achieved via a one-pot three-component reaction of cyclohexylisocyanide, an aromatic aldehydes, and phenols in DMF for 10 h with good yields.     

Flow visualization of supersonic transverse jet over Mach 2 freestream of a sharp cone

Graphical abstract  

     

Visualizations of the flow around a swimmer in turbulent regime

Graphical abstract  

     

Development of a model of focal pneumococcal pneumonia in young rats

Background  

A recently licensed pneumococcal conjugate vaccine has been shown to be highly effective in the prevention of bacteremia in immunized children but the degree of protection against pneumonia has been difficult to determine.     

Breakup modes of a laminar hollow water jet

Graphical Abstract  

     

A Canadian national survey of attitudes and knowledge regarding preventive vaccines

Background  

Vaccines have virtually eliminated many diseases, but public concerns about their safety could undermine future public health initiatives.     

Entry of inclined hydrophobic and hydrophilic circular cylinders into water

Graphical Abstract  

     

Pattern of distribution and cycling of SLOB,Slowpoke channel binding protein,in <Emphasis Type="Italic">Drosophila</Emphasis>

Background  

SLOB binds to and modulates the activity of the Drosophila Slowpoke (dSlo) calcium activated potassium channel. Recent microarray analyses demonstrated circadian cycling of slob mRNA.     

Two-layer exchange flows over a dune: effect of large-scale bottom roughness

Graphical Abstract  

     

Probing local innate immune responses after mucosal immunisation

Background  

Intranasal immunisation is potentially a very effective route for inducing both mucosal and systemic immunity to an infectious agent.     

Sex-dependent gene expression in early brain development of chicken embryos

Background  

Differentiation of the brain during development leads to sexually dimorphic adult reproductive behavior and other neural sex dimorphisms. Genetic mechanisms independent of steroid hormones produced by the gonads have recently been suggested to partly explain these dimorphisms.     

Slowing of axonal regeneration is correlated with increased axonal viscosity during aging

Background  

As we age, the speed of axonal regeneration declines. At the biophysical level, why this occurs is not well understood.     

Numerical visualization of counter rotating vortex ring formation ahead of shock tube generated vortex ring

Graphical Abstract  

     

Coherent structures of the turbulent round jet in different focal lengths

Graphical abstract  

     

Growth Cone Pathfinding: a competition between deterministic and stochastic events

Background  

Growth cone migratory patterns show evidence of both deterministic and stochastic search modes.     

The life of a vortex in an axisymmetric jet

Graphical Abstract  

     

Imprinting modulates processing of visual information in the visual wulst of chicks

Background  

Imprinting behavior is one form of learning and memory in precocial birds. With the aim of elucidating of the neural basis for visual imprinting, we focused on visual information processing.     

Levamizole enhances immune responsiveness to intra-dermal and intra-muscular hepatitis B vaccination in chronic hemodialysis patients

Background  

Hemodialysis patient are at high risk for hepatitis B virus (HBV) infection.     

Usefulness of event-related potentials in the assessment of mild cognitive impairment

Background  

The aim of this study was to determine if changes in latencies and amplitudes of the major waves of Auditory Event-Related Potentials (AERP), correlate with memory status of patients with mild cognitive impairment (MCI) and conversion to Alzheimer's disease (AD).