THE COUPLE MOTION BETWEEN VESSEL WALL AN DBLOOD IN THE ENTRANCE REGION OF A TAPERED VESSEL

ＴＨＥＣＯＵＰＬＥＭＯＴＩＯＮＢＥＴＷＥＥＮＶＥＳＳＥＬＷＡＬＬＡＮＤＢＬＯＯＤＩＮＴＨＥＥＮＴＲＡＮＣＥＲＥＧＩＯＮＯＦＡＴＡＰＥＲＥＤＶＥＳＳＥＬＣｅｎＲｅｎ－ｊｉｎｇ（岑人经）ＱｉｎＣｈａｎ（秦婵）ＴａｎＺｈｅ－ｄｏｎｇ（谭哲东）（ＳｏｕｔｈＣ...     

Boundary layer development of pulsatile blood flow in a tapered vessel

Assuming that the tapered angle is small,the problems of developing flow under unsteady oscillatory condition are studied in this paper.The formula of velocity distribution is obtained.The analyses for the results show that the blood flow in a converging tapered vessel remains a developing flow throughout the length,and the effects of tapered angle on the developing flow are increased with the increment of the tapered angle.     

Stress concentrations around multiple windows in a high-pressure vessel

A pressure vessel with four radial windows was designed in which to conduct equation-of-state experiments at pressures up to 1 GPa (145,000 psi). To determine the relative safety of the vessel, the stress distribution in the cylindrical sidewalls, particularly the stress concentration near the window openings, was studied. Conventional analysis was used for the initial evaluation but was found to give somewhat higher stress values than were actually present. Better determinations of the stress distribution were obtained by photoelastic analysis of a model of the pressurevessel linear and by proof tests with strain gages of the actual liner and the assembled pressure vessel. Apparently, the tapered sapphire windows, loaded in compression by the internal pressure in the vessel, modify the stress distribution sufficiently to allow operation at higher pressures than otherwise would be attainable. Design features of the pressure vessel are presented, together with a synoptic stress analysis, a photoelastic analysis, and results of the strain-gage studies.     

Role of response to changes in flow rate in the regulation of vessel radius and blood flow

Estimates are presented for the effect of susceptibility of the inner surface of the blood vessel wall to shear stress on changes in diameter and volume blood flow rate. The model of thin-walled vessel with radius controlled by two parameters is used. The effect of rheological factors, hematocrit, and oxygen content in blood on the value of vessel response to a change in shear stress is considered. The estimates showed that the contribution of the vessel response in question to a change in blood volume flow rate amounts tens per cent. The influence of rheological (Fahraeus and Fahraeus-Lindqvist) effects on flow rate lies within several per cent. The role of the vessel response considered increases with anaemia: at low hematocrit its contribution to increase in flow rate exceeds 10%. Variation of oxygen concentration within the normal range has almost no effect on the hemodynamic parameters. With hypoxia, on the contrary, the participation of this response on changes in flow rate weakens: in severe hypoxia decrease in blood flow rate owing to a change in oxygen concentration equals approximately 9%.     

The blood flow and the motion of vessel wall

The correlation problem between the blood flow and the motion of vessel wall in the mammalian circulatory system is discussed in this paper. Supposing the blood flow is under the stable oscillatory condition, a set of formulas for velocity distribution, pressure distribution, displacement of vessel wall and constraining stress are obtained. Kuchar’s formulas are extended from steady flow to unsteady oscillatory flow by means of the formulas obtained in this paper. The problem of elasticity effect of vessel wall is also discussed.     

Pulsatile blood flow in a resistance vessel

The quasi-one-dimensional Newtonian fluid flow in an active vessel in which the inlet pressure oscillates about a mean value is considered. The vascular wall is assumed to display the Bayliss effect and a reaction to changes in blood flow. The first is characterized by the dependence of the contractility of the vascular smooth-muscle cells on the intravascular pressure and the second by the sensitivity of the endothelial cells to the wall shear stress. The dependence of the period-average radius and blood flow rate on the mean value and pulsation amplitude and frequency of the inlet pressure is investigated numerically. The characteristics are compared for the passive vessel, the vessel with the Bayliss effect, and the vessel with both reactions.     

局部扩张动脉管血液振荡流的切应力分布

本文求解局部缓慢扩张动脉管中血液振荡流的基本方程，得到血管内血液的流速与压力梯度的关系。通过导出压力梯度沿局部扩张管轴向的变化特性。建立利用扩张段上游血管均匀段中心流速波形确定局部扩张管中血液流的速度和切应力分布的方法，文章以人体颈动脉余弦扩张为例进行分析。详细讨论了局部扩张对血管壁切应力及其梯度分布的影响。数值结果表明，在与刚性均匀管中管壁切应力沿轴向保持不变不同，在局部扩张段，管壁切应力将随着血管半径的增大而减小，因而管壁切应力梯度一般不为零，甚至在某些位置达到相当大的数值。另外，随着血管扩张程度的增加，管壁切应力还将进一步减小，而且管壁切应力梯度也将进一步增大，血管扩张导致管壁切应力的这些变化将直接影响血管壁的结构和功能，使其产生适应性的变化。     

计算动脉血管发展流动的新差分格式

在引用守恒型N—S方程和SIMPLE方法的基础上，对血管发展流动的控制方程提出了新的差分格式。算例结果表明：本差分格式对血管发展流动的数值研究是可行的。     

平行平板流动腔脉动流切应力的计算

高度远小于横向和纵向几何尺寸的矩形平行平板流动腔是人们用以体外研究细胞在切应力作用下力学行为的主要工具之一。大多数研究者主要对定常层流情进行研究。本文通过对矩形平行平板流动腔内的层流脉动流进行详细分析,给出腔内速和腔室底部切应力的准确计算公式。当Ｗｏｍｅｒｓｌｅｙ数较小时,准确公式简化为准定常公式。数值计算结果表明,在脉动流条件下,对于人们常用的流动腔几何尺寸,准定常公式具有相当高的精度。这为在脉     

Steady flow through a slender tapered vessel with a partially permeable wall and closed end

We study the flow of a viscous fluid through a slender tapered tube whose radius may reduce to zero. The vessel is closed at the end, so that the flow is made possible owing to the fact that a portion of the tube wall is permeable. The smallness of the tube aspect ratio is exploited using an upscaling technique leading to a degenerate differential equation for pressure. Solutions are found either in explicit form or as power series expansions. This class of flows may represent, though in a largely approximated way, the blood flow though a coronary artery.     

Pulsatile flows in a lateral aneurysm anchored on a stented and curved parent vessel

We present particle tracking velocimetry measurements and flow visualization of pulsatile flow fields in a stented cerebrovascular lateral aneurysm model with a wide ostium anchored on a curved parent vessel. Among the stent parameters, the blocking ratioC _α ranging from 0% to 75% was selected to study its effect on the changes of intra-aneurysmal hemodynamics for the reference of minimally invasive endovascular aneurysm treatment. The Womersley number was 3.9 and the mean, peak, and minimal Reynolds numbers based on the bulk average velocity and diameter of the parent vessel were 600, 850, and 300, respectively. The results are characterized in terms of velocity vector field, coded streak images, region averaged velocity, vorticity, and wall shear stress. A critical range ofC _α related to the inflow location as well as the shape and number of intra-aneurysmal vortices is identified. The intra-aneurysmal flow activity, vortex strength, and wall shear stress are found to decrease with increasingC _α. Among theC _α examined,C _α=75% is the most favorable in attenuating the risk of aneurysmal rupture and promoting intra-aneurysmal thrombus.     

Interstitial fluid flow: simulation of mechanical environment of cells in the interosseous membrane

In vitro experiments have shown that subtle fluid flow environment plays a significant role in living biological tissues,while there is no in vivo practical dynamical measurement of the interstitial fluid flow velocity.On the basis of a new finding that capillaries and collagen fibrils in the interosseous membrane form a parallel array,we set up a porous media model simulating the flow field with FLUENT software,studied the shear stress on interstitial cells’ surface due to the interstitial fluid flow,and analyzed the effect of flow on protein space distribution around the cells.The numerical simulation results show that the parallel nature of capillaries could lead to directional interstitial fluid flow in the direction of capillaries.Interstitial fluid flow would induce shear stress on the membrane of interstitial cells,up to 30 Pa or so,which reaches or exceeds the threshold values of cells’ biological response observed in vitro.Interstitial fluid flow would induce nonuniform spacial distribution of secretion protein of mast cells.Shear tress on cells could be affected by capillary parameters such as the distance between the adjacent capillaries,blood pressure and the permeability coefficient of capillary’s wall.The interstitial pressure and the interstitial porosity could also affect the shear stress on cells.In conclusion,numerical simulation provides an effective way for in vivo dynamic interstitial velocity research,helps to set up the vivid subtle interstitial flow environment of cells,and is beneficial to understanding the physiological functions of interstitial fluid flow.     

箱形梁剪力滞效应分析中的翘曲位移函数及广义内力研究

以薄壁箱梁的弯曲计算理论为基础,从分析翼缘板的面内剪切变形和弯曲剪力流的分布规律入手,从理论上证明二次抛物线是箱形梁剪力滞效应分析中的合理翘曲位移函数。选取剪力滞效应引起的附加挠度作为广义位移,用基于最小势能原理的能量变分法建立箱形梁剪力滞效应分析的控制微分方程和边界条件。对箱梁横截面上新出现的广义内力给出严密定义,并建立了剪力滞翘曲应力的简便计算公式,它与初等梁弯曲应力公式具有相同的形式。对一个简支箱梁模型的计算表明,计算值与实测值吻合良好,从而证实了本文的分析方法和建立的公式是正确的。不同于弯矩的分布,剪力滞广义力矩具有快速衰减的分布特征。对集中荷载作用下的简支箱梁算例,剪力滞效应使其跨中挠度增大达12%,工程实践中必须认真对待。     

Mathematical modeling and parametric investigation of blood flow through a stenosis artery

In this study, a mathematical model is formulated to examine the blood flow through a cylindrical stenosed blood vessel. The stenosis disease is caused because of the abnormal narrowing of flow in the body. This narrowing causes serious health issues like heart attack and may decrease blood flow in the blood vessel. Mathematical modeling helps us analyze such issues. A mathematical model is considered in this study to explore the blood flow in a stenosis artery and is solved numerically with the finite difference method. The artery is an elastic cylindrical tube containing blood defined as a viscoelastic fluid. A complete parametric analysis has been done for the flow velocity to clarify the applicability of the defined problem. Moreover, the flow characteristics such as the impedance, the wall shear stress in the stenotic region, the shear stresses in the throat of the stenosis and at the critical stenosis height are discussed. The obtained results show that the intensity of the stenosis occurs mostly at the highest narrowing areas compared with all other areas of the vessel, which has a direct impact on the wall shear stress. It is also observed that the resistive impedance and wall shear pressure get the maximum values at the critical height of the stenosis.

     

Magnetically assisted gas-solid fluidization in a tapered vessel:Part II Dimensionless bed expansion scaling

The article presents an effort to create dimensionless scaling correlations of the overall bed porosity in the case of magnetically assisted fluidization in a tapered vessel with external transverse magnetic field. This is a stand of portion of new branch in the magnetically assisted fluidization recently created concerning employment of tapered vessels. Dimensional analysis based on "pressure transform" of the initial set of variables and involving the magnetic granular Bond number has been applied to deve...     

刚性圆管中血液周期振荡流的切应力分布

本文通过求解圆管内血液振荡流的基本方程，求得圆管内血液流的压力梯度与切应力之间的关系式。在此基础上，详细讲座了圆管中轴向流速和切变率谐波的变化规律，指出流速谐波和切变率谐波的幅值都将随着谐波次数的增大而逐渐减小。为了使所得结果便于应用。文章通过管轴向中心线流速与压力梯度之间的关系式，进一步给出一种利用管轴向中心线流速计算管内切应力分布的简便方法。该方法用于检测活体血管内血液振荡流的切应力分布，具有操作简单，精度较高的优点。最后，以人体颈动脉为例，讨论血液周期振荡流的切应力的分布特性。发现在任意时刻，除了邻近管壁处切应力急剧增大到一定数值之外，沿管截面切应力分布相当均匀且接近于零，呈现出与定常流不同的切应力分布特征。     

The steady/pulsatile flow and macromolecular transport in T-bifurcation blood vessels

IntroductionThefluiddynamicsofbloodcyclesystemplayanimportantroleinthepathogenesisofatherosclerosis.ThephysiologicalanatomyfoundthattheatherosclerosisappearsoftenatthebifurcationorcurvedflowareatoallkindsofRefs.[1 ,2 ] .Theshearstressvariesgreatlyinthoseareaandinfluencesthemacromoleculartransportacrossthebloodwall[3,4].Thus ,theinvestigationoftheflowandmacromoleculartransportinthesecomplexbloodvesselaandthecorrelationbetweenthemareinterestingtoresearchers.Intheseaspect,Liepschstudiedtheflowi…     

Photoelastic-coating analysis of a thermoplastic,rectangular-parallelepiped pressure vessel

Photoelastic-coating techniques were used to analyze the full-field stress distribution on the critical surface of a cast thermoplastic, rectangular-parallelepiped pressure vessel. Data were presented to illustrate principal-stress magnitudes and directions obtained by the oblique-incidence method. Results obtained from a rectangular-rosette strain gage and from the post-yield residual-fringe pattern were supportive of the experimental techniques employed.     

The spherical vessel with anisotropic creep properties considering large strains

The effect of material anisotropy on creep of pressurized thick-walled spherical vessel has been discussed considering the large strain theory. It is found that the creep strain varies with varying anisotropy of the material. The results obtained for the anisotropic case have been compared with those obtained for the isotropic case and it is observed that the stress and strain distribution in the wall of the vessel is strikingly different for the two cases.     

Simulation of heat and chemical reactions on Reiner Rivlin fluid model for blood flow through a tapered artery with a stenosis

In the present article, we have analyzed the effects of heat and mass transfer on Reiner Rivlin fluid model for blood flow through a tapered artery with a stenosis. The constitutive equations for a Reiner Rivlin fluid have been modelled in cylindrical coordinates. A perturbation series in dimensionless Reiner Rivlin fluid parameter (λ ₁ ≪ 1) have been used to obtain explicit forms for the velocity, temperature, concentration, resistance impedance, wall shear stress and shearing stress at the stenosis throat. The graphical results of different type of tapered arteries i.e. converging tapering, diverging tapering, non-tapered artery have been examined for different parameters of interest.