Two-phase non-linear model for blood flow in asymmetric and axisymmetric stenosed arteries

The pulsatile flow of a two-phase model for blood flow through axisymmetric and asymmetric stenosed narrow arteries is analyzed, treating blood as a two-phase model with the suspension of all the erythrocytes in the core region as the Herschel-Bulkley material and plasma in the peripheral layer as the Newtonian fluid. The perturbation method is applied to solve the resulting non-linear implicit system of partial differential equations. The expressions for various flow quantities are obtained. It is found that the pressure drop, plug core radius, wall shear stress increase as the yield stress or stenosis height increases. It is noted that the velocity increases, longitudinal impedance decreases as the amplitude increases. For asymmetric stenosis, the wall shear stress increases non-linearly with the increase of the axial distance. The estimates of the increase in longitudinal impedance to flow of the two-phase Herschel-Bulkley material are significantly lower than those of the single-phase Herschel-Bulkley material. The results show the advantages of two-phase flow over single-phase flow in small diameter arteries with stenosis.     

A two-fluid model for pulsatile flow in catheterized blood vessels

The pulsatile flow of blood through a catheterized artery is analyzed, assuming the blood as a two-fluid model with the suspension of all the erythrocytes in the core region as a Casson fluid and the peripheral region of plasma as a Newtonian fluid. The resulting non-linear implicit system of partial differential equations is solved using perturbation method. The expressions for shear stress, velocity, flow rate, wall shear stress and longitudinal impedance are obtained. The variations of these flow quantities with yield stress, catheter radius ratio, amplitude, pulsatile Reynolds number ratio and peripheral layer thickness are discussed. It is observed that the velocity distribution and flow rate decrease, while, the wall shear, width of the plug flow region and longitudinal impedance increase when the yield stress increases. It is also found that the velocity increases, but, the longitudinal impedance decreases when the thickness of the peripheral layer increases. The wall shear stress decreases non-linearly, while, the longitudinal impedance increases non-linearly when the catheter radius ratio increases. The estimates of the increase in the longitudinal impedance are considerably lower for the present two-fluid model than those of the single-fluid model.     

一种确定均匀动脉壁面切应力的非线性方法

从Ling和Atabek提出的``局部流'理论出发，提出一种利用测量血液黏度、管轴上 的血流速度、压力和管径波形计算均匀动脉管壁切应力的非线性方法. 将这种方法与柳兆荣 等提出的利用测量血液黏度、管轴上的血流速度和平均管径计算切应力的线性方法比较，结 果表明，当管壁脉动幅度较小时，两种方法计算的压力梯度、流速剖面和管壁切应力差别较 小；而当管壁脉动幅度增大时，两种方法计算的压力梯度、流速剖面和管壁切应力差别增大. 对于小幅脉动均匀动脉，用线性方法计算管壁切应力有较高的精度；而对于大变形 均匀动脉，则需要考虑非线性因素对管壁切应力的影响. 由于作为输入量的血液黏度、轴心 血流速度、压力波形和管径波形可在活体上通过无损伤或微损伤的检测方法得到， 所提出的计算切应力的方法为在体或离体研究切应力与动脉重建的关系提供了方法学基础.     

Performance modeling and analysis of blood flow in elastic arteries

Nomenclature　　τ　　wallshearstressγshearrateτy yieldstressηc Cassonviscosityktheconsistencyindexnnon_Newtonianindexτp shearstressofthepthelementωangularvelocityRvessel’sradiusCwavespeedM　　magneticparameter (Hartmannnumber)u,w　velocitycomponentinther_andz_directions,respectivelyP　　pressureα　　unsteadinessparameter k , R meanparametersTp relaxationtimeofthepthelementρ densityIntroductionTheimportancetoatherogenesisofarterialflowphenomenasuchasflowseparation ,recirculationands…     

Magnetohydrodynamic approach of non-Newtonian blood flow with magnetic particles in stenosed artery

The non-Newtonian blood flow, together with magnetic particles in a stenosed artery, is studied using a magneto-hydrodynamic approach. The wall slip condition is also considered. Approximate solutions are obtained in series forms under the assumption that the Womersley frequency parameter has small values. Using an integral transform method, analytical solutions for any values of the Womersley parameter are obtained.Numerical simulations are performed using MATHCAD to study the influence of stenosis and magnetic field on the flow parameters. When entering the stenosed area, blood velocity increases slightly, but increases considerably and reaches its maximum value in the stenosis throat. It is concluded that the magnitude of axial velocity varies considerably when the applied magnetic field is strong. The magnitude of maximum fluid velocity is high in the case of weak magnetic fields. This is due to the Lorentz's force that opposes motion of an electrically conducting fluid. The effect of externally transverse magnetic field is to decelerate the flow of blood. The shear stress consistently decreases in the presence of a magnetic field with increasing intensity.     

Computational Modelling of Non-Newtonian Effects on Flow in Channels with Moving Wall Indentations

Non-Newtonian effects in a channel with moving wall indentations are assessed numerically by a finite volume method for solving the unsteady incompressible Navier-Stokes equations and using a power-law model exhibiting shear thinning viscosity and Casson's model as the constitutive equations for the non-Newtonian fluid. The computations show that for a non-Newtonian fluid, there are differences in the velocity profiles and in the structure and size of the reversed flow regions as compared with the corresponding Newtonian fluid. The comparison of non-Newtonian and Newtonian wall shear stress reveals a slight decrease in the magnitude on the average for the non-Newtonian case, eventually resulting in the strength of the “wave train” being slightly weaker than those corresponding to a Newtonian fluid.     

Mathematical modelling of couple stresses on fluid flow in constricted tapered artery in presence of slip velocity-effects of catheter

This paper explores the mathematical model for couple stress fluid flow through an annular region. The above model is used for studying the blood flow be-tween the clogged （stenotic） artery and the catheter. The asymmetric nature of the stenosis is considered. The closed form expressions for the physiological parameters such as impedance and shear stress at the wall are obtained. The effects of various geomet-ric parameters and the parameters arising out of the fluid considered are discussed by considering the slip velocity and tapering angle. The study of the above model is very significant as it has direct applications in the treatment of cardiovascular diseases.     

局部狭窄血管中血液振荡流的速度和切应力

本文建立一种分析局部缓慢狭窄血管中血液振荡流的数学模型，给出了血液的轴向流速，径向流速和切应力的包含压力梯度项的解析表达式，并讨论了血管内由局部狭窄引起的压力梯度沿轴向变化的规律。文章以局部余弦狭窄为例进行数值计算，详细讨论上游均匀管段压力梯度的定常部分和不同次谐波对狭窄管段内流速和切应力的影响。数值结果表明，与均匀管情况相比，在狭窄段内，血液振荡流轴向流速无论平均值还是脉动幅值均明显增大，且径向流速不再为零。但径向流速仍远小于轴向流速。同时，切应力也不再仅由轴向流速梯度提供，径向流速梯度也将产生切应力，但是在计算管壁切向上的切应力时，径向流速梯度的贡献仍相当大。与均匀管管壁切应力沿流运方向保持恒定不同。狭窄管管壁切应力（平均值和脉动值）将随着狭窄高度的增大而增大，在狭窄最大高度处达到最大，因而沿流动方向产生了较大的切应力梯度。     

A Two-Layer Mathematical Model of Blood Flow in Porous Constricted Blood Vessels

In this paper, we discussed a mathematical model for two-layered non-Newtonian blood flow through porous constricted blood vessels. The core region of blood flow contains the suspension of erythrocytes as non-Newtonian Casson fluid and the peripheral region contains the plasma flow as Newtonian fluid. The wall of porous constricted blood vessel configured as thin transition Brinkman layer over layered by Darcy region. The boundary of fluid layer is defined as stress jump condition of Ocha-Tapiya and Beavers–Joseph. In this paper, we obtained an analytic expression for velocity, flow rate, wall shear stress. The effect of permeability, plasma layer thickness, yield stress and shape of the constriction on velocity in core & peripheral region, wall shear stress and flow rate is discussed graphically. This is found throughout the discussion that permeability and plasma layer thickness have accountable effect on various flow parameters which gives an important observation for diseased blood vessels.     

Self-similar solution of the unsteady mixed convection flow in the stagnation point region of a rotating sphere

An analysis is performed to present a new self-similar solution of unsteady mixed convection boundary layer flow in the forward stagnation point region of a rotating sphere where the free stream velocity and the angular velocity of the rotating sphere vary continuously with time. It is shown that a self-similar solution is possible when the free stream velocity varies inversely with time. Both constant wall temperature and constant heat flux conditions have been considered in the present study. The system of ordinary differential equations governing the flow have been solved numerically using an implicit finite difference scheme in combination with a quasilinearization technique. It is observed that the surface shear stresses and the surface heat transfer parameters increase with the acceleration and rotation parameters. For a certain value of the acceleration parameter, the surface shear stress in x-direction vanishes and due to further reduction in the value of the acceleration parameter, reverse flow occurs in the x–component of the velocity profiles. The effect of buoyancy parameter is to increase the surface heat transfer rate for buoyancy assisting flow and to decrease it for buoyancy opposing flow. For a fixed buoyancy force, heating by constant heat flux yields a higher value of surface heat transfer rate than heating by constant wall temperature.     

The Falkner–Skan Wedge Flows of Power-Law Fluids Embedded in a Porous Medium

The non-Darcy flow characteristics of power-law non-Newtonian fluids past a wedge embedded in a porous medium have been studied. The governing equations are converted to a system of first-order ordinary differential equations by means of a local similarity transformation and have been solved numerically, for a number of parameter combinations of wedge angle parameter m, power-law index of the non-Newtonian fluids n, first-order resistance A and second-order resistance B, using a fourth-order Runge–Kutta integration scheme with the Newton–Raphson shooting method. Velocity and shear stress at the body surface are presented for a range of the above parameters. These results are also compared with the corresponding flow problems for a Newtonian fluid. Numerical results show that for the case of the constant wedge angle and material parameter A, the local skin friction coefficient is lower for a dilatant fluid as compared with the pseudo-plastic or Newtonian fluids.     

Laminar,transitional and turbulent annular flow of drag-reducing polymer solutions

Mean and rms axial velocity-profile data obtained using laser Doppler anemometry are presented together with pressure-drop data for the flow through a concentric annulus (radius ratio κ = 0.506) of a Newtonian (a glycerine–water mixture) and non-Newtonian fluids—a semi-rigid shear-thinning polymer (a xanthan gum) and a polymer known to exhibit a yield stress (carbopol). A wider range of Reynolds numbers for the transitional flow regime is observed for the more shear-thinning fluids. In marked contrast to the Newtonian fluid, the higher shear stress on the inner wall compared to the outer wall does not lead to earlier transition for the non-Newtonian fluids where more turbulent activity is observed in the outer wall region. The mean axial velocity profiles show a slight shift (～5%) of the location of the maximum velocity towards the outer pipe wall within the transitional regime only for the Newtonian fluid.     

Analytical solutions for equations of unsteady flow of non-newtonian fluids in tube

This paper presents analytical solutions to the partial differential equations for unsteady flow of the second-order fluid and Maxwell fluid in tube by using the integral transform method. It can be used to analyse the behaviour of axial velocity and shear stress for unsteady flow of non-Newtonian visco-elastic fluids in tube, and to provide a theoretical base for the projection of pipe-line engineering.     

The micropolar fluid model for blood flow through a tapered artery with a stenosis

A micropolar model for axisymmetric blood flow through an axially nonsymmetreic but radially symmetric mild stenosis tapered artery is presented. To estimate the effect of the stenosis shape, a suitable geometry has been considered such that the axial shape of the stenosis can be changed easily just by varying a parameter （referred to as the shape parameter）. The model is also used to study the effect of the taper angle Ф. Flow parameters such as the velocity, the resistance to flow （the resistance impedance）, the wall shear stress distribution in the stenotic region and its magnitude at the maximum height of the stenosis （stenosis throat） have been computed for different values of the shape parameter n, the taper angle Ф, the coupling number N and the micropolar parameter m. It is shown that the resistance to flow decreases with increasing the shape parameter n and the micropolar parameter m while it increases with increasing the coupling number N. So, the magnitude of the resistance impedance is higher for a micropolar fluid than that for a Newtonian fluid model. Finally, the velocity profile, the wall shear stress distribution in the stenotic region and its magnitude at the maximum height of the stenosis are discussed for different values of the parameters involved on the problem.     

Self-similar solution of the unsteady flow in the stagnation point region of a rotating sphere with a magnetic field

The unsteady flow and heat transfer of a viscous incompressible electrically conducting fluid in the forward stagnation point region of a rotating sphere in the presence of a magnetic field are investigated in this study. The unsteadiness in the flow field is caused by the velocity at the edge of the boundary layer and the angular velocity of the rotating sphere, both varying continuously with time. The system of ordinary differential equations governing the flow is solved numerically. For some particular cases, an analytical solution is also obtained. It is found that the surface shear stresses in x- and y-directions and the surface heat transfer increase with the acceleration, the magnetic and the rotation parameters whether the magnetic field is fixed relative to the fluid or body, except that the surface shear stress in x-direction and the surface heat transfer decrease with increasing the magnetic parameter when the magnetic field is fixed relative to the body. For a certain value of the acceleration parameter, the surface shear stress in the x-direction vanishes while the surface shear stress in the y-direction and the surface heat transfer remain finite. Also, below a certain value of the acceleration parameter, reverse flow occurs in the x-component of the velocity profile. Received on 18 May 1998     

弯曲动脉的血流动力学数值分析

利用计算流体力学的理论和方法对弯曲动脉中的血流动力学进行数值分析，是研究心血管疾病流体动力学机理的一种行之有效的方法。本文将升主动脉、主动脉弓和降主动脉联系起来作为弯曲动脉几何模型，给出了血液流动的边界条件以及计算条件。根据生理脉动流条件，对狗的弯曲动脉几何模型内发展中的血液流动进行了有限元数值模拟，并利用可视化方法对血液流动的轴向速度、二次流、壁面切应力等计算结果进行了分析。研究结果表明，在弯管内侧壁处，同时存在主流方向和二次流方向的回流，此处容易形成涡流。弯管内侧壁比外侧壁的壁面切应力具有更强的脉动性。     

The Rayleigh and Stokes problems with an incompressible non-Newtonian fluid

Summary The Rayleigh problem or impulsive motion of a flat plate has been solved using a perturbation scheme when the surrounding fluid is representable by the constitutive equations of Oldroyd or Coleman and Noll. The shear stress and normal stress at the wall were expressed analytically for this unsteady motion. Further, an exact solution of the equations was found for a special case of the constitutive equations.The motion of the fluid above a harmonically oscillating plate or the Stokes problem has been determined for a special non-Newtonian fluid. The penetration of the shear wave into the fluid, the energy dissipation, the velocity profiles and the shear and normal stresses at the wall were expressed and compared to an equivalent Newtonian fluid.Some of the features of these non-Newtonian fluids were examined in simple shearing flows, and techniques to calculate some of the material constants discussed.     

Natural convection of non-Newtonian power-law fluid over axisymmetric and two-dimensional bodies of arbitrary shape in fluid-saturated porous media

Numerical analysis of the free convection coupled heat and mass transfer is presented for non-Newtonian power-law fluids with the yield stress flowing over a two-dimensional or axisymmetric body of an arbitrary shape in a fluid-saturated porous medium. The governing boundary layer equations and boundary conditions are cast into a dimensionless form by the similarity transformation. The resulting system of equations is solved by a finite difference method. The parameters studied are the rheological constants, the buoyancy ratio, and the Lewis number. Representative velocity, temperature, and concentration profiles are presented and discussed. It is found that the results depend strongly on the values of the yield stress parameter and the power-law index of the non-Newtonian fluid.     

重力和接触角对表面张力贮箱内液体流动的影响

采用流体体积函数方法数值模拟板式表面张力贮箱内液体的流动过程. 主要考虑了不同重力加速度和接触角等因素的影响. 发现在接触角等于10° 的前提下, 重力加速度小于10-2g₀, 液体沿着外侧导流叶片爬升至贮箱顶部; 当重力加速度小于10-3g₀ 时, 重力加速度的减小对液体爬升速度的影响较小. 在爬升过程中, 导流叶片附近液体的速度呈逐渐减小的趋势, 且重力加速度越小, 初始速度越大. 接触角对液体的爬升高度也会产生影响,接触角越小, 液体爬升至顶部的时间越短; 当接触角大于45° 时, 外侧导流叶片附近的液面不能爬升至顶端. 另外, 接触角越大, 液面高度的斜率越小,导流叶片附近液体的初始速度也越小.      

GPU accelerated simulations of three-dimensional flow of power-law fluids in a driven cube

Newtonian fluid flow in two- and three-dimensional cavities with a moving wall has been studied extensively in a number of previous works. However, relatively a fewer number of studies have considered the motion of non-Newtonian fluids such as shear thinning and shear thickening power law fluids. In this paper, we have simulated the three-dimensional, non-Newtonian flow of a power law fluid in a cubic cavity driven by shear from the top wall. We have used an in-house developed fractional step code, implemented on a Graphics Processor Unit. Three Reynolds numbers have been studied with power law index set to 0.5, 1.0 and 1.5. The flow patterns, viscosity distributions and velocity profiles are presented for Reynolds numbers of 100, 400 and 1000. All three Reynolds numbers are found to yield steady state flows. Tabulated values of velocity are given for the nine cases studied, including the Newtonian cases.