Separation of the alkaloids deoxypeganine,peganol, and deoxyvasicinone by the HPLC method

Institute of Chemistry of Plant Substances Academy of Sciences of the Uzbek SSR, Tashkent. Scientific Center for Chromatography, Academy of Sciences of the Uzbek SSR. Institute of the Chemistry and Physics of Polymers, Academy of Sciences of the Uzbek SSR, Tashkent. Iranslated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 297–298, March–April, 1991.     

Effect of the irradiation of cotton seeds with pulses of concentrated light on the composition of the cottonseed oil

The presowing irradiation of cotton seeds with pulses of concentrated light (PCL) causes a change in a number of indices of the oil. When the seeds are stored, oxidative processes in them are intensified. In the oil of the harvested seeds some indices are restored.Institute of the Chemistry of Plant Substances of the Academy of Sciences of the Uzbek SSR, Tashkent, and S. V. Starodubtsev Institute of Technical Physics of the Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 777–780, November–December, 1980.     

Synthesis and membrane activity of new derivatives of 2,3-benzo-18-crown-6

The acylation of 2,3-benzo-18-crown-6 with carboxylic acids in the presence of polyphosphoric acid has given new acyl derivatives which have been reduced to the corresponding alkyl derivatives. The ionophoric activities of the compounds have been investigated on mitochondrial membranes.Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 634–637, September–October, 1983.     

4',4”- and 4',5”-di-sec-butyl-2,3:11,12-dibenzo-18-crown-6 — An ionophore for magnesium in natural and model systems

The ionophoric properties of the di-sec-butyl derivatives of dibenzo-18-crown-6 have been studied in natural and model membranes. It has been shown that the di-sec-butyl substituents in the benzene rings of dibenzo-18-crown-6 impart to the cyclopolyether the properties of an ionophore for magnesium. The Mg²⁺/Ca²⁺ selectivity of the cyclopolyether investigated was 4.8 according to results obtained on artifical membranes and mitochondria.Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 234–239, March–April, 1981.     

Molecular and crystal structure of sophoridine N-oxide

The spatial structure of natural sophoridine N-oxide has been studied by x-ray structural analysis. It has been shown that when sophoridine is oxidized, rings B and C, which have the boat form, are deformed in the direction of the twist form.Institute of Bioorganic Chemistry of the Academy of Sciences of the Uzbek SSR, Tashkent, Institute of Crystallography of the Academy of Sciences of the USSR, Moscow, and V. I. Lenin Tashkent State University. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 588–596, September–October, 1981.     

Isolation and antibiotic properties of cis-hexadeca-4,7,10,13-tetraenoic acid from the algaScenedesmus obliquus UA-2-6

Summary By the method of checking antibiotic activity, conditions have been selected for the isolation of cis-hexadeca-4,7,10,13-tetraenoic acid from the fatty-acid fractions of the lipids ofScenedesmus obliquus UA-2-6. Its structure has been confirmed and it has been established that this acid possesses a broad spectrum of antibiotic action.Institute of Microbiology, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 379–385, May–June, 1978.     

Difference-perturbation spectra of iodotyrosines and iodothyronines in polyethyleneglycols

The difference-perturbation absorption spectra of monoiodotyrosine, diiodotyrosine, triiodothyronine, and thyroxine with low- and high-molecular-mass polyethyleneglycols as perturbants have been measured and characterized. The SDP spectra, and their intensity and the position of the main maximum depend on the number of iodine atoms and the state of ionization of the hydroxyl in accordance with their electron-accepting properties.Institute of Physiology, Uzbek SSR Academy of Sciences, Tashkent. Institute of Biochemistry, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, Vol. 6, pp. 840–845, November–December, 1989.     

Synthesis and anticholinesterase activites of a number of derivatives of the alkaloid lupinine

A series of new lupinine derivatives and their methiodides has been synthesized. It has been shown that they are powerful reversible inhibitors of acetylcholinesterase and butyrylcholinesterase.A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 513–515, July–August, 1990.     

Stereospecific analysis of the triacylglycerols of a cottonseed oil hydrogenate and its fractions

A cottonseed oil hydrogenate has been fractionated into three fractions: high-melting, medium-melting, and liquid. It has been established that the fat of the second fraction, because of its physicochemical indices, consistency, and the distribution of the saturated fatty acyl radicals in the extreme positions of the TAG molecules, can be regarded as a cocoa butter substitute.Institute of the Chemistry of Plant Substances of the Uzbek SSR Academy of Sciences, Tashkent. Institute of Bioorganic Chemistry of the Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 509–513, July–August, 1987.     

Inhibition of transport (Na+, K+)-ATPase by cardenolides of the strophanthidin group and a study of the structure-activity relationship

Summary A comparative study of the inhibiting action on transport (Na⁺,K⁺)-ATPase of 15 derivatives of strophanthidin and four rhamnosides of other aglycones have been made on the microsomal fraction of the cells of the rat cerebral cortex.It has been shown that the method of determining the activity of cardiotonic substances by determining the lethal dose and the enzyme test give completely comparable results. Both biological methods objectively reflect the characteristic features of the chemical structure of the cardenolides.Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 188–194, March–April, 1976.     

Homogeneous lecithin from cottonseed meal

The possibility of using industrial cottonseed meal for the production of homogeneous lecithin has been shown.Institute of the Chemistry of Plant Sciences, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 295–296, May–June, 1984.     

Solanidine and diacetylsevedine from Korolkowia sewerzowii

Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 440–441, May–June, 1991.     

Demethylenedelpheline — A new diterpene alkaloid from Delphinium corumbosum

Abu Ali Ibn Sina [Avicenna] Tadzhik State Medical Institute, Dushanbe. Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 50–51, January–February, 1989.     

Monitoring the purity of antigepolin with the aid of chromatography in a thin layer of sorbent

A. S. Sadykcv Institute of Bioorganic Chemistry, Academy of sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 296–297, March–April, 1991.     

Benzoxazolinones. II. Synthesis of 3-vinylbenzoxazolinones and 3-vinylbenzoxazolinethione

A method has been developed for obtaining 3-vinylbenzoxazolinones and 3-vinylbenzoxazolinethione. It has been shown that it is also possible to obtain 3-methylbenzoxazolinethione by this method in good yield (76%).Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 553–556, July–August, 1980.     

Some products of the coupling of gossypol with diazotized amines

Summary A series of products of the coupling of gossypol with diazotized amines has been obtained. It has been established that they are monoadducts. The possibility of using them as dyes for cotton fabric has been shown.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 607–609, September–October, 1976.     

Comparative study of the cytotoxins of the venom of the central asian cobraNaja naja oxiana by the intrinsic-fluorescence method

The intrinsic fluorescence of cytotoxin V_C1 and V_C5 from the venom of the Central Asian cobra due to the tyrosine residues and differing with respect to quantum yield for these two polypeptides because of the nonidentity of the microenvironments of the tyrosyl residues has been measured and characterized. The dependence of the quantum yield on the pH and the temperature also indicate this nonidentity.Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 226–228, March–April, 1986.     

Spontaneous dehydrogenation of tetrahydro-2,3-trimethylenequinazolines and -quinazolones

Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 149–150, January–February, 1991.     

Preparation of immobilized lipases of the fungusRhizopus microsporus UzLT-1 and their properties

Summary It has been shown that adsorption on AE-cellulose partially protected by the palmitoyl residue is an effective method of immobilizing the lipases ofRhizopus microsporus. The kinetics of the lipases are characterized by substrate inhibition. Immobilization considerably increases the heat stability of the lipases.Institute of Microbiology, Academy of Sciences of the Uzbek SSR, Tashkent. All-Union Scientific-Research Institute of Applied Enzymology, Vil'nyus. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 624–629, September–October, 1978.     

Dimeric tropane alkaloids

Literature information on dimeric alkaloids of the tropane series is generalized.Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 447–455, July–August, 1991.