Synthesis and crystal structures of cobalt(III) and zinc(II) complexes derived from 4-chloro-2-[(2-morpholin-4-ylethylimino)methyl]phenol with urease inhibitory activity

A new mononuclear cobalt(III) complex, [CoL₂(N₃)]₂ · CH₃OH (I), and a new mononuclear zinc(II) complex, [ZnLCl(CH₃OH)] (II) (HL = 4-chloro-2-[(2-morpholin-4-ylethylimino)methyl]phenol), were prepared and structurally characterized by elemental analyses, infrared spectroscopy, and single- crystal X-ray diffraction. The crystal of I is monoclinic: space group P2₁/c, a = 18.742(2) Å, b = 15.197(2) Å, c = 25.646(2) Å, β = 125.996(3)°, V = 5909.8(11) ų, Z = 4. The crystal of II is monoclinic: space group P2₁/c, a = 7.257(1) Å, b = 24.707(2) Å, c = 9.637(1) Å, β = 101.557(2)°, V = 1692.9(3) ų, Z = 4. The Co atom in I is in an octahedral coordination, and the Zn atom in II is in a trigonal-bipyramidal coordination. The urease inhibitory test shows that complex I has strong urease inhibitory activity, while complex II has no activity.     

Synthesis and crystal structures of binuclear complexes of cobalt(II) and cadmium(II) diisobutyldithiophosphinates with hexamethylenetetramine

Heteroligand complexes [Co₂(HMTA)(iso-Bu₂PS₂)₄] (I) (μ_eff = 4.67 μB) and [Cd₂(HMTA)(iso-Bu₂PS₂)₄] (II) have been synthesized. Single crystals of compounds I and II have been obtained. The crystals are monoclinic: a = 32.622(2) Å, b = 9.4891(6) Å, c = 21.7570(13) Å, β = 125.774(1)^o, V = 5464.3(6) Å,³, Z = 4, ρ_calcd = 1.331 g/cm³ for I; a = 34.6092(7) Å, b = 9.5595(2) Å, c = 22.3473(5) Å, β = 127.144(1)^o, V = 5893.5(2) Å, Z = 4, ρ_calcd = 1.355 g/cm³ for II; space group for both complexes C2/c. Structures I and II are based on discrete binuclear molecules. The coordination polyhedra of the Co and Cd atoms are distorted tetragonal pyramids NS₄, with the bases formed by four S atoms of two bidentate chelating ligand iso-Bu₂PS ₂ ^? and the axial vertices occupied by N atoms of bidentate bridging HMTA ligand. The character of interaction of the molecules in structures I and II is considered.     

Crystal structure of adducts of copper(II) acetylacetonate and hexafluoroacetylacetonate with 4-aminopyridine

Single crystal X-ray diffraction is used to investigate two synthesized β-diketonate complexes of copper(II) with aminopyridine: Cu(4-NH₂Py)(aa)₂ (I) and Cu(4-NH₂Py)(hfa)₂ (II). The crystals of I and II have a monoclinic system; the unit cell parameters of I are: P2₁/n space group, a = 8.2921(3) Å, b = 14.7243(5) Å, c = 13.4970(4) Å, β = 102.426(1)°, V = 1609.32(9) ų, Z = 4; for II: C2/c space group, a = 23.5704(5) Å, b = 11.4977(2) Å, c = 16.0285(3) Å, β = 109.265(1)°, V = 4100.6(1) ų, Z = 8. The structures of I and II are molecular; they are composed of isolated molecules. The coordination polyhedron of the copper atom is formed by the O atoms of two acetylacetonate ligands (Cu-O 1.940(2)–2.171(2) I and the O atoms of two hexafluoroacetylacetonate ligands (Cu-O 1.940(2)–2.215(3) Å) in II. The molecules of 4-NH₂Py are bonded to the copper atom via the nitrogen atom of the aromatic ring (Cu-N 2.008(2) Å in I and Cu-N 1.978(3) Å in II). Noncoordinated amino groups join the molecules of the complexes together by means of N-H…O hydrogen bonds.     

Synthesis and crystal structure of Fe(III) and Al(III) complexes with 2-diphenylacetyl-1,3-indandione

Iron(III) and aluminum(III) complexes with 2-diphenylacetyl-1,3-indandione (HL) have been synthesized. The structures of the obtained compounds FeL₃(I) and AlL₃(II) were studied. The isostructural crystals are monoclinic, I: Z = 8, space group P2_1/c, a = 16.061(3) Å, b = 16.658(3) Å, c = 22.015(4) Å, β = 111.41(3)°; II: Z = 8, space group P2_1/c, a = 16.115(14) Å, b = 16.476(8) Å, c = 21.949(20) Å, β = 111.04(11)°. The structural units of crystals I and II are neutral molecules in which each ligand is bidentately coordinated to a central metal atom through the oxygen atom of the acyl keto group and an oxygen atom of the indandione fragment to form a six-membered chelate ring. In the crystals, neutral molecules I and II form pseudodimers due to stacking of indandione moieties of two adjacent coordination spheres and additional C-H…O contacts. Each pseudodimer is in contact with six neighboring dimers also through hydrogen bonds C-H…O to form an infinite framework.     

Synthesis,crystal structures,and antimicrobial activity of copper(II) and zinc(II) complexes derived from 2-bromo-4-chloro-6-[(2-morpholin-4-ylethylimino)methyl]phenol

An end-to-end azido-bridged dinuclear copper(II) complex [Cu₂L₂(μ_1,3-N₃)](NO₃) (I) and a mononuclear zinc(II) complex [ZnCl₂(HL)] ? CH₃OH (II), where L is 2-brom-4-chloro-6-[(2-morpholin- 4-ylethylimino)methyl]phenolate, have been prepared and characterized by elemental analyses, IR, and single crystal X-ray crystallographic determination (CIF files CCDC nos. 1415217 (I), 1415218 for (II)). The crystal of I is monoclinic: space group C2/c, a = 28.684(2), b = 7.1787(5), c = 18.292(1) Å, β = 117.887(3)°, V = 3329.1(4) ų, Z = 4. The crystal of II is monoclinic: space group P2₁/c, a = 10.8207(9), b = 12.3398(7), c = 14.9477(7) Å, β = 93.473(3)°, V = 1992.2(2) ų, Z = 4. The Schiff base ligand in I coordinates to the Cu atom through the phenolate O, imine N, and morpholine N atoms, while the Schiff base ligand in II coordinates to the Zn atom through the phenolate O and imine N atoms, with the morpholine N atom protonated. The effect of these complexes on the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans was studied.     

Synthesis and crystal structure of zinc(II) and manganese(II) complexes of 2-(diphenylacetyl)indandione-1,3

Zinc(II) and manganese(II) complexes of 2-(diphenylacetyl)indandione-1,3 (HL) were synthesized. Crystals of [M(DMSO)₂L₂] · CHCl₃, where M= Zn^(II) (I) and Mn^(II) (II), obtained from chloroform plus dimethyl sulfoxide (DMSO) mixture were found to be isostructural based on the similarity of their unit cell parameters and unit cell volumes. The crystals are triclinic, Z = 2, space group P \(\bar 1\); a = 10.422(1) Å, b = 11.929(1) Å, c = 20.429(1) Å, α = 73.616(1)°, β = 85.095(1)°, γ = 77.586(1)° for complex I; a = 10.436(1) Å, b = 12.297(1) Å, c = 19.924(2) Å, α = 78.138(2)°, β = 87.625(2)°, γ = 82.048(2)° for complex II. X-ray structural analysis of complex I was carried out. For complex II, the structure was not refined because all of its atoms are each disordered over three to five positions. The two DMSO molecules in complex I coordinate the central metal atoms in the monodentate mode via their donor oxygen atoms to occupy an axial position and an equatorial position in an octahedral polyhedron. The other four positions are occupied by the four oxygen atoms of the two deprotonated ligands L^? coordinated in the bidentate-cyclic mode. The outer sphere of complex I contains the solvating chloroform molecule.     

Synthesis and structure of diethylenetriammonium tetrachloroaurates(III)

The (DienH₃)[AuCl₄]₃ · H₂O (I) and (DienH₃)₂[AuCl₄]Cl₅ (II) compounds were obtained by the reaction of HAuCl₄ with diethylenetriamine trihydrochloride (DienH₃Cl₃) in hydrochloric acid. The compounds were characterized by elemental analysis, X-ray diffraction, thermogravimetry, and IR spectroscopy. Crystals of I and II are monoclinic with space group P2₁/n. For I, a = 12.2314(3) Å, b = 14.6077(5) Å, c = 13.2680(5) Å, β = 106.7350(10)°, V = 2270.22(13) ų, Z = 8. For II, a = 6.62990(10) Å, b = 17.9026(5) Å, c = 10.3661(3) Å, β = 101.9230(10)°, V = 1203.83(5) ų, Z = 2. Both structures are ionic. The gold atoms in I and II have a 4 + 2 coordination environment. The Au-Cl bond lengths are within 2.276–2.294 Å, and the axial Au…Cl contacts are within 3.315–3.405 Å. The diethylenetriammonium cation in I and II has different conformations.     

Synthesis and crystal structures of the zinc(II) complexes with a tridentate Schiff base (1-pyridin-2-ylethylidene)pyridin-2-ylmethylamine

Two new isostructural zinc(II) complexes, [ZnCl₂(L)] (I) and [ZnBr₂(L)] (II), derived from the Schiff base ligand (1-pyridin-2-ylethylidene)pyridin-2-ylmethylamine (L), have been prepared and characterized by physicochemical methods and single-crystal X-ray crystallography. The crystal of I is monoclinic: space group P2₁/c, a = 11.699(3) Å, b = 8.460(2) Å, c = 14.766(3) Å, β = 99.686(3)°, V = 1440.6(6) ų, Z = 4. The crystal of II is monoclinic: space group P2₁/n, a = 8.166(2) Å, b = 15.153(3) Å, c = 11.966(2) Å, β = 96.964(2)°, V = 1469.7(5) ų, Z = 4. The geometry of the pentacoordinated zinc atoms in both complexes is best described as a square pyramid.     

Synthesis and crystal structures of tetraacetylethylenediamine and <Emphasis Type="Italic">N</Emphasis>-(2-ammoniumethyl)carbamate

Two ethylenediamine derivatives—N-(2-ammoniumethyl)carbamate HN(COO^?)CH₂CH₂N⁺H₃ (I) and tetraacetylethylenediamine (H₃CC(O))₂NCH₂CH₂N(C(O)CH₃)₂ (II) (synthesized for the first time)—have been synthesized and characterized by X-ray crystallography. Compounds I and II are isolated as minor admixtures upon an attempt to synthesize ethylenediamine complexes of lanthanum and neodymium nitrates, respectively. The crystals of I and II are monoclinic: a = 7.778 Å, b = 8.060 Å, c = 7.568 Å, β = 95.73°, Z = 4, space group P2₁/c (I); a = 5.946, b = 10.255, c = 9.343 Å, β = 95.72°, Z = 2, space group P2₁/c (II). The bond lengths and bond angles lie within the corresponding standard values. Compounds I and II have different conformations of the N-C-C-N ethylenediamine moiety: gauche in I and trans in II, and the corresponding torsion angles are equal to 66.6° and 180°, respectively.     

Synthesis and crystal structures of cobalt(III) and zinc(II) complexes with Schiff bases

Two new cobalt(III) and zinc(II) complexes, [Co(L¹)₂ (H₂O)] · ClO₄ (I) and [Ni(L²)₂ (H₂O)₂] · 2ClO₄ (II), where L¹ is the deprotonated form of 5-methoxy-2-[(2-morpholin-4-ylethylimino)methyl]phenol, and L² is the zwitterionic form of 2-[(2-isopropylaminoethylimino)methyl]-5-methoxyphenol, were synthesized and structurally characterized by elemental analyses, IR spectra, and single-crystal X-ray diffraction. The crystal of I is monoclinic: space group P2₁/c, a = 11.1512(4), b = 28.2424(11), c = 10.9655(4) Å, β = 95.746(2)°, V = 3436.1(2) ų, Z = 4. The crystal of II is triclinic: space group P2₁/c, a = 8.1441(2), b = 10.4531(3), c = 10.8849(3) Å, α = 84.0240(10)°, β = 76.9800(10)°, γ = 74.2280(10)°, V = 867.92(4) ų, Z = 1. Complex I consists of a mononuclear cobalt(III) complex cation and a perchlorate anion. Complex II consists of a crystallographic centrosymmetric mononuclear nickel(II) complex cation and two perchlorate anions. Each metal atom in the complexes is in an octahedral coordination.     

Synthesis,crystal structures,and characterization of a new substituted 1,2,4-triazole and its two Co(II)/Mn(II) complexes

A new triazole-substituted ligand H₂L (H₂Trza = 3-amino-1H-1,2,4-triazole-5-acetate) and its two new isomorphic compounds [M(HTrza)₂(_H2O)₂] ? 2H₂O (Co(I) and Mn(II)) have been synthesized and characterized structurally. Their X-ray crystal structures (CIF files CCDC nos. 906893 for I and 906892 for II) show that H₂L belongs to a tetragonal system; space group P4₃ with a = b = 5.0445(13), c = 27.054(10) Å; Z = 4. Complex I belongs to a monoclinic system; space group P2₁/n with a = 7.6543(8), b = 7.3453(8), c = 13.6283(14) Å; β = 91.5990(10)°, Z = 2. Complex II belongs to a triclinic system; space group with a = 6.8550(15), b = 8.0630(18), c = 15.173(4) Å; α = 84.794(4)°, β = 79.005(3)°, γ = 73.779(4)°, Z = 2. X-ray analysis demonstrates that compound H₂L is found to contain a H₂Trza and a lattic water molecule; complexes I and II are discrete mononuclear species. The central Co(II) and Mn(II) atoms exhibit octahedral coordinations, type 4 + 2. In two compounds, the coordination entities are further organized via hydrogenbonding interactions to generate uniform supramolecular networks. Thermal stabilities of two compounds were examined by thermogravimetric analysis.     

Hexafluorosilicates of cobalt(II) complexes with dimethylsulfoxide and dimethylformamide

New double complexes [Co(DMSO)₆][SiF₆] ? 2H₂O (I) and [Co(DMF)₃(H₂O)₃][SiF₆] ? DMF (II) have been synthesized and studied by IR spectroscopy and X-ray diffraction. Crystals of complex I belong to the tetragonal symmetry system, space group R3?, Z = 3, a = 11.8232(3) Å, c = 18.4699(5) Å, V = 2235.97(10) ų, ρ_calc = 1.573 g/cm³. Crystals of complex II are triclinic, space group P1?, Z = 2, a = 8.6264(4) Å, b = 10.1419(4) Å, c = 13.9657(6) Å, α = 100.847(2)°, β = 98.549(2)°, γ = 93.479(2)°, V = 1181.71(9) ų, ρ_calc = 1.539 g/cm³.     

Synthesis and crystal structures of (2.2.2-cryptand)rubidium chloride and bromide hydrates

Two complexes, (2.2.2-cryptand)rubidium chloride and bromide hydrates [Rb(Crypt-222]Hal · 3.5H₂O (Hal = Cl (I) and Br (II)), are synthesized. The structures of isomorphic crystals of compounds I and II are studied by X-ray diffraction analysis. The crystals are trigonal: space group P \(\overline 3 \), Z = 2; I: a = 11.810 Å, c = 11.302 Å; II: a = 11.890 Å, c = 11.402 Å. The structures are solved by a direct method and refined by the full-matrix least-squares method in the anisotropic approximation to R = 0.060 (I) and 0.077 (II) for 2650 (I) and 2700 (II) independent reflections (CAD-4 automated diffractometer, λMoK _α radiation). In crystals of complexes I and II, the [Rb(Crypt-222)]⁺ cation of the host-guest type lies on the crystallographic axis 3 and has the approximate symmetry D ₃. In complexes I and II, the coordination polyhedron of the Rb⁺ cation is a two-base-centered trigonal prism somewhat distorted to an antiprism. The crystals of compounds I and II contain H-bonded disordered cubes of the water molecules and Cl^? or Br^? anions.     

Synthesis,crystal structure,and antibacterial activity of oxovanadium(V) complexes derived from <Emphasis Type="Italic">N</Emphasis>'-[1-(5-fluoro-2-hydroxyphenyl)methylidene]nicotinohydrazide and <Emphasis Type="Italic">N</Emphasis>'-(5-fluoro-2-hydroxybenzylidene)-2-hydroxynaphthylhydrazide

Two new oxovanadium(V) complexes, [VOL¹(OCH₃)(CH₃OH)] (I) and [VOL²(OCH₃)] (II), where L¹ and L² are the di-anionic form of N'-[1-(5-fluoro-2-hydroxyphenyl)methylidene]nicotinohydrazide and N'-(5-fluoro-2-hydroxybenzylidene)-2-hydroxynaphthylhydrazide, respectively, have been synthesized and characterized by elemental analysis, FT-IR spectra, and single crystal X-ray determination (CIF files CCDC nos. 891852 (I), 891853 (II)). The crystal of I is monoclinic: space group P2₁/c, a = 8.061(1), b = 15.293(2), c = 13.471(2) Å, ß = 92.595(2)°, V = 1658.8(4) ų, Z = 4. The crystal of II is monoclinic: space group P2₁/n, a = 7.4454(9), b = 8.0833(9), c = 28.906(2) Å, ß = 92.644(2)°, V = 1737.8(3) ų, Z = 4. The V atom in I is in an octahedral coordination, and that in II is in a square-pyramidal coordination. The antibacterial activity of the compounds against various bacteria was assayed.     

Syntheses and crystal structures of (2.2.2-cryptand)potassium chloride and (2.2.2-cryptand)ammonium bromide<Subscript>(0.75)</Subscript>chloride<Subscript>(0.25)</Subscript> hydrates

Two new complexes were synthesized, namely, 7: 2 (2.2.2-cryptand)potassium chloride and (2.2.2-cryptand)ammonium bromide_(0.75)chloride_(0.25) hydrates: [M(Crypt-222)]⁺ · Hal^? · 3.5H₂O, where M = K, Hal = Cl (I) and M = NH₄, Hal = Br_0.75Cl_0.25 (II). The structures of two isomorphous crystals were studied by X-ray diffraction analysis. Trigonal (space group P \(\bar 3\), Z = 2) structures I (a = 11.763 Å, c = 11.262 Å) and II (a = 11.945 Å, c = 11.337 Å) were solved by direct methods and refined by the full-matrix least-squares method in the anisotropic approximation to R = 0.057 (I) and 0.065 (II) for all 2626 (I) and 1654 (II) independent measured reflections (CAD-4 automated diffractometer, λMoK _α). In structures I and II, the host-guest [M(Crypt-222)]⁺ complex cation lies on the threefold crystallographic axis and has the approximate D ₃ symmetry. In complex I, the coordination polyhedron of the K⁺ cation (CN = 8) is a bicapped trigonal prism somewhat distorted toward an antiprism. Complexes I and II contain H-bonded disordered cubes of the water molecules and the Cl^? or Br^? anions.     

(18-Crown-6)sodium tribromide and (18-crown-6)potassium triiodide (with an admixture of bromodiiodide): Synthesis and crystal structure

Two crystalline host-guest complexes are synthesized and studied using X-ray diffraction analysis: (18-crown-6)sodium tribromide [Na(18-crown-6)]⁺ · Br ₃ ^? (I) and (18-crown-6)potassium tribromide (with an admixture of bromodiiodide) [K(18-crown-6)]⁺ · (Br_0.25I_2.75)^? (II). The structures of compound I (space group P2₁/_{n, a} = 8.957 Å, b = 8.288 Å, c = 14.054 Å, β = 104.80°, Z = 2) and compound II (space group Cc, a = 8.417 Å, b = 15.147 Å, c = 17.445 Å, β = 99.01°, Z = 4) are solved by a direct method and refined by the full-matrix least-squares method in the anisotropic approximation to R = 0.098 (I) and 0.036 (II) for all 2311 (I) and 2678 (II) independent measured reflections on a CAD-4 automated diffractometer (λMoK _α). Similar crystalline complexes I and II exist as infinite chains of alternating complex cations and trihalide anions linked to each other through weak Na-Br or K-I coordination bonds. In [Na(18-crown-6)]⁺ and [K(18-crown-6)]⁺ complex cations, the Na⁺ or K⁺ cation (coordination number is eight) is located in the center of the cavity of the 18-crown-6 ligand and coordinated by the six O atoms and two terminal Br or I atoms of two trihalide anions lying on opposite sides of the rms plane of the crown ligand.     

Syntheses,characterization, and crystal structures of two dinuclear nickel(II) and copper(II) complexes with Schiff bases

The phenolic azide bridged dinuclear nickel(II) complex, [Ni₂(L¹)₂(N₃)(H₂O)(μ_1,1-N₃)] · EtOH (I), and the thiocyanate bridged dinuclear copper(II) complex, [Cu₂(L²)₂(μ_1,1-NCS)₂] (II), where L¹ and L² are the deprotonated forms of 2-mothoxy-6-[(2-piperidin-1-ylethylimino)methyl]phenol and 2,4-dichloro-6-[(2-methylaminoethylimino)methyl]phenol, respectively, were synthesized and characterized by elemental analysis, IR spectra, and single-crystal X-ray diffraction. The crystal of I is orthorhombic: space group Pbca, a = 12.172(1), b = 20.953(1), c = 29.779(2) Å, V = 7594.8(9) ų, Z = 8. The crystal of II is monoclinic: space group P2₁/n, a = 8.7615(11), b = 19.672(2), c = 16.568(2) Å, β = 99.449(2)°, V = 2816.9(6) ų, Z = 4. The Ni atoms in I are in octahedral coordinations, and the Cu atoms in II are in square-pyramidal coordinations.     

Synthesis and crystal structures of two zinc(II) complexes derived from 4-bromo-2-(cyclopentyliminomethyl)phenol with different solvents

Two new mononuclear zinc(II) complexes, [ZnL₂] (I) and [ZnL₂] · 2MeOH (II) (HL = 4-bromo-2-(cyclopentyliminomethyl)phenol), were synthesized by the reaction of the Schiff base HL with zinc acetate in ethanol and methanol solutions, respectively. Both complexes were characterized by elemental analyses and single-crystal X-ray diffraction. The crystal of I is orthorhombic: space group Pbca, a = 14.711(3), b = 13.223(3), c = 24.870(5) Å, V = 4837.8(18) ų, Z = 8. The crystal of II is monoclinic: space group C2/c, a = 20.581(5), b = 10.660(3), c = 15.428(4) Å, β = 119.919(3)°, V = 2933.7(13) ų, Z = 4. The Zn atom in each complex is four-coordinated by two imine N and two phenolic O atoms, forming a tetrahedral geometry. Complex II possesses crystallographic two-fold rotation axis symmetry.     

Synthesis,crystal structures,and antibacterial activities of Schiff base nickel(II) and cadmium(II) complexes with tridentate Schiff bases

Reaction of tridentate Schiff bases with nickel and cadmium salts in methanol afforded two new mononuclear complexes, [Ni(L¹)₂] (I) and [Cd(L²)₂] (II), where L¹ and L² are the anions of 2-bromo-4-chloro-6-[(3-dimethylaminopropylimino)methyl]phenol (HL¹) and 2-bromo-4-chloro-6-[(3-morpholin-4-ylpropylimino)methyl]phenol (HL²), respectively. The complexes were characterized by singlecrystal X-ray diffraction (CIF files CCDC nos. 1428653 (I) and 1428654 for (II)), FT-IR, and elemental analysis. Complex I crystallizes in the monoclinic space group P2 ₁/c, with a = 8.8216(8), b = 14.0424(8), c = 11.8687(12) Å, β = 111.238(2)°, V = 1370.4(2) ų, Z = 2. Complex II crystallizes in the monoclinic space group P2 ₁/n, with a = 9.6774(4), b = 15.8970(6), c = 20.3144(7) Å, β = 90.408(2)°, V = 3125.1(2) ų, Z = 4. The metal atoms in the complexes are coordinated by two tridentate Schiff base ligands, forming octahedral coordination. The free Schiff bases and the complexes were assayed for antibacterial activities. Both complexes are more active against the bacteria than the free Schiff bases. Complex II has the MIC value of 0.39 μg mL^–1 against Bacillus subtilis.     

Crystal structures of rhodium(III) aqua ion with tetrahedral anions

The crystal structures of compounds of the composition [Rh(H₂O)₆]₂(SO₄)₃·5H₂O (I) and [Rh(H₂O)₆]PO₄ (II) are determined. Crystallographic data for I: a = 7.272(9) Å, b = 27.047(1) Å, c = 12.464(9) Å, β = 97.038(10)°, P2₁ space group, Z = 4, d _x = 2.184 g/cm³; for II: a = 9.746(6)Å, b = 6.877(7) Å, c = 23.623(6) Å, β = 100.601(10)°, C2/c space group, Z = 8, d _x = 2.611 g/cm³. Compounds are analyzed by IR spectroscopy and powder XRD. Crystalline phase I is well soluble in water, whereas II is almost insoluble.