共查询到20条相似文献,搜索用时 31 毫秒
1.
Ya Juan Xu Tun Hai Xu Jun Ying Yang Sheng Xu Xie Yue Liu Yun Shan Si Dong Ming Xu 《中国化学快报》2010,21(5):580-583
<正>Two new furostanol glycoside,26-O-β-D-glucopyranosyl-(25S)-5α-furost-3β,22α,26-triol-3-O-β-D-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-β-D-galactopyranoside(1) and 26-O-β-D-glucopyranosyl-(25S)-5α-furost-20(22)-en-2α,3β,26-triol-3-O-β-D-glucopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside(2) were isolated fromthe fruits of Tribulus terrestris L.The structures of two new furostanol saponins were elucidated by spectroscopic methods. 相似文献
2.
It was well known that furostan saponin was a kind of natural products with a broadrange of promising pharmaceutical properities1. Structurally, furostan saponins usuallyhave bidesmosidic sugar moieties substituted at 3-OH and 26-OH position2. However,fur… 相似文献
3.
A furostanol saponin mixture and a known phytoecdysteroid were isolated from the roots of Helleborus orientalis Lam. Their structures were established as 26-[(β-D-glucopyranosyl)oxy]-22α-hidroxyfurosta-5,25(27)-dien-1β,3β,11α-triol (1a), 26-[(β-D-glucopyranosyl)oxy]-22α-methoxyfurosta-5,25(27)-dien-1β,3β,11α-triol (1b), and 20-hydroxy-β-ecdyson-3-O-β-D-glycoside (2). Acid hydrolysis of 1a,b gave (1β,3β,11α,22α)-22,26-dimethoxyfurosta-5,25(27)-dien-1,3,11-triol (aglycone 1) and of 2 gave 20-hydroxy-β-ecdyson (aglycone 2). Their structures were elucidated by spectral analysis.
Published in Khimiya Prirodnykh Soedinenii, No. 1, pp. 75–77, January–February, 2007. 相似文献
4.
Kun Zou Jun Wu Ming Du Chuang Liu Zi Chun Tang jun Zhi Wang 《中国化学快报》2007,18(1):65-68
A pair of diastereoisomeric furostanol saponins was obtained from the n-butanol fraction of methanol extract from Tupistra chinensis rhizomes,a folk medicine of Shennongjia Forest District of Hubei Province.Their structures were determined,on the basis of chemical and spectroscopic evidences. 相似文献
5.
A New Furostanol Glycoside from Polygonatum odoratum 总被引:3,自引:0,他引:3
HaiLinQIN ZhiHongLI PengWANG 《中国化学快报》2003,14(12):1259-1260
A new furostanol component glycosylated only at C-26 was isolated from the rhizomes of Polygonatum odoratum(Mill.)Druce,and its structure was characterized as 22-hydroxy-25(R and S)furost-5-en-12-on-3β,22,26-triol 26-O-β-D-glucopyranoside on the basis of spectroscopic techniques and chemical methods. 相似文献
6.
G. V. Pirtskhalava M. B. Gorovits T. T. Gorovits N. K. Abubakirov 《Chemistry of Natural Compounds》1979,15(4):446-452
From a methanolic extract of the bulbs ofAllium turcomanicum Rgl. we have isolated a new furostanol glycoside, turoside C (I). An acid hydrolysate was found to contain the aglycone — neoagigenin (II) — and the sugars D-xylose, D-glucose, and D-galactose in a ratio of 1:4:1. The structure of the furostanol (I) has been established by methylation, enzymatic hydrolysis, and oxidative cleavage, and also by the oxidative cleavage of (II), as (25S)-5α-furostan-2α,3β,6β,22α,26-pentaol 26-O-β-D-glucopyranoside 3-O-{[O-β-D-xylopyranosyl-(1→3)]-[O-β-D-glucopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)]-O-β-D-glucopyranosyl-(1→4)-β-D-galacto-pyranoside}. 相似文献
7.
YongChunYANG JianGongSHI ShengYangHUANG 《中国化学快报》2002,13(12):1185-1188
Two new furostanol oligoglycosides named as aspacochioside A(1)and B(2) were isolated from the roots of Asparagus cochinchinensis (Lour.)Merr..Their structures were clucidated to be 3-O-[{α-L-rhamnopyranosyl-(1→4)}{β-D-glucopyranosyl}]-26-O-[β-D-glucopy-ranosyl]-(25S)-5β-furostane-3β,22α,26-triol 1 and 3-O-[{α-L-rhamnopyranosyl-(1→4)}{β-D-glu-copyeransoyl}]-26-O-[β-D-glucopyranosyl]-22α-methoxy-(25S)-5β-furostane-3β,26-diol 2 on the basis of spectroscopic techniques and chemical methods. 相似文献
8.
A new furostanol saponin, (25R)-26-O-(α-d-glucopyranosyl)-(1→2)-α-l-rhamnopyranosyl-furost-5-ene-3β, 22α, 26-triol-3-O-α-d-glucopyranoside (1), together with four known compounds 2–5 were isolated from the ethanolic extract of the stems of Dendrobium chrysanthum Lindl. The structures of these new compounds were identified by extensive spectroscopic analysis including 1D and 2D NMR and HR-ESI-MS, as well as chemical methods. Compounds 1–3 were isolated from D. chrysanthum for the first time. Furthermore, the inhibitory effects of the compounds on tumor cells were evaluated, and compounds 1–2 exhibited significant cytotoxic activities potentially against SPC-A1, MCF-7 and HeLa human cancer cell lines. Compounds 3–5 showed inhibitory activity against the SPC-A1 and MCF-7. 相似文献
9.
Application of high‐performance countercurrent chromatography for the isolation of steroidal saponins from Liriope plathyphylla 下载免费PDF全文
Soo‐Jung Choi Janggyoo Choi Heejin Jeon Soo Kyung Bae Jaeyoung Ko Jinwoong Kim Kee Dong Yoon 《Journal of separation science》2015,38(1):18-24
High‐performance countercurrent chromatography (HPCCC) with electrospray light‐scattering detection was applied for the first time to isolate a spirostanol and a novel furostanol saponin from Liriope platyphylla. Due to the large differences in KD values between the two compounds, a two‐step HPCCC method was applied in this study. The primary HPCCC employed methylene chloride/methanol/isopropanol/water (9:6:1:4 v/v, 4 mL/min, normal‐phase mode) conditions to yield a spirostanol saponin ( 1 ). After the primary HPCCC run, the solute retained in the stationary phase (SP extract) in HPCCC column was recovered and subjected to the second HPCCC on the n‐hexane/n‐butanol/water system (1:9:10 v/v, 5 mL/min, reversed‐phase mode) to yield a novel furostanol saponin ( 2 ). The isolated spirostanol saponin was determined to be 25(S)‐ruscogenin 1‐O‐β‐d ‐glucopyranosyl (1→2)‐[β‐d ‐xylopyranosyl (1→3)]‐β‐d ‐fucopyranoside (spicatoside A), and the novel furostanol saponin was elucidated to be 26‐O‐β‐d ‐glucopyranosyl‐25(S)‐furost‐5(6)‐ene‐1β‐3β‐22α‐26‐tetraol‐1‐O‐β‐d ‐glucopyranosyl (1→2)‐[β‐d ‐xylopyranosyl‐(1→3)]‐β‐d ‐fucopyranoside (spicatoside D). 相似文献
10.
Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes
Kun Zou Jun Zhi Wang Jun Wu Yuan Zhou Chuang Liu Fei Jun Dan Ya Xiong Zhang Jin Yang 《中国化学快报》2007,18(10):1239-1242
Two furostanol saponins were obtained from the n-butanol fraction of methanol extract from Tupistra chinensis rhizomes,a folk medicine of Shennongjia Forest District of Hubei Province.Their structures were determined as (25S)-26-O-(β-D-glucopyranosyl)- furost-1β,3β,22α,26-tetrol-3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (1) and (25R)- 26-O-(β-D-glucopyranosyl)-furost-1β,3β22α,26-tetrol 3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→2)-β-D-glu- copyranoside (2),on basis of chemical and spectroscopic evidences.1 and 2 displayed marked inhibitory action towards COX-2 production in macrophages of the rat abdomen induced by LPS at 20μg/mL. 相似文献
11.
A New Enolate Furostanoside from Asparagus Filicinus 总被引:1,自引:0,他引:1
Xiao Dong CONG Wen Cai YE Chun Tao CHE Department of Pharmacohnosy China Pharmaceutical University Nanjing Department of Phytochemistry China Pharmaceutical University Nanjing School of Chinese Medicine The Chinese University of Hong Kon 《中国化学快报》2000,11(9)
The roots of Asparagus filicinus Buch.-Ham are used to treat lung diseases such asbronchitis, pneumonities and cough in folk medicinel. Some steroidal glycosides havebeen isolated and characterized from the roots of this plant by several research groups'-'.In this paper, we report the isolation of a new unusual furostanol glycoside possessing anenolate moiety, whose strUcture was determined by I D and ZD NMR methods, FABMS,and hydrolysis. Bioassay results showed that the compound exhibit… 相似文献
12.
A. P. Shchelochkova Yu. S. Vollerner K. K. Koshoev 《Chemistry of Natural Compounds》1980,16(4):386-392
Results are given which confirm the structure of the furostanol glycoside from tomato seeds forming wastes of the preserving industry. From a butanolic extract of the seeds ofLycopersicum esculentum Mill. we have isolated the furostanol glycoside tomatoside A (I) the structure of which has been established as 25(S)-5α-furostan-3β,22α,26-triol 26-O-β-D-glucopyranoside 3-O-[O-β-D-glucopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside]. At the same time, by enzymatic and chemical transformations three new spirostanol glycosides of neotigogenin have been obtained: tomatoside B (III), which is 25(S)-5α-spirostan-3β-ol 3-O-[O-β-D-glucopyranosyl-(1→2)-β-D-galactopyranoside], 25(S)-5α-spirostan-3β-ol 3-O-[O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside] (V), and 25(S)-5α-spirostan-3β-ol 3-O-β-D-galactopyranoside (IV). 相似文献
13.
Kang LP Liu ZJ Zhang L Tan DW Zhao Y Zhao Y Chen HB Ma BP 《Magnetic resonance in chemistry : MRC》2007,45(9):725-733
An analysis of the polar extracts from Allium ascalonicum L. led to the isolation of two new furostanol saponins (compound 1 and 2) and two known furostanol saponins (compound 3 and 4). On the basis of 1D and 2D NMR (including (1)H, (13)C NMR, (1)H--(1)H COSY, HSQC, TOCSY, HMBC, and NOESY), FAB-MS spectrometry, and chemical methods, their structures were elucidated as (25R)-26-O-beta-D-glucopyranosyl-22-hydroxy-5alpha-furost-2-one-3beta, 5, 6beta, 26-tetraol-3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside (ascalonicoside C, 1), (25R)-26-O-beta-D-glucopyranosyl-22-methoxy-5alpha-furost-2-one-3beta, 5, 6beta, 26-tetraol- 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside (ascalonicoside D, 2), (25R)-26-O-beta-D-glucopyranosyl-22-hydroxy-5-ene-furostan-3beta, 26-diol-3-O-alpha-L-rhamnopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->4)-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (dichotomin, 3), and (25R)-26-O-beta-D-glucopyranosyl-22-hydroxy-5-ene-furostan-3beta, 26-diol-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-arabinofuranosyl-(1-->4)]-beta-D- glucopyranoside (parisaponin I, 4). 相似文献
14.
Yajuan Xu Tunhai Xu Yue Liu Shengxu Xie Yunshan Si Tonghua Liu Dongming Xu 《Chemistry of Natural Compounds》2010,46(2):242-245
The structures of five furostanol glycosides (1–5), of which the 26-O-β-D-glucopyranosyl-(25S),5α-furost20(22)-en-12-one-2α,3β,26-triol-3-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside (1) was new, from the leaves of Tribulus terrestris L. were established using chemical and NMR spectroscopic methods. 相似文献
15.
He‐Shui Yu Peng Zou Xin‐Bo Song Li‐Ping Kang Yi‐Xun Liu Xu Pang Jie Zhang Jing Fu Yang Zhao Cheng‐Qi Xiong Da‐Wei Tan Li‐Juan Zhang Bai‐Ping Ma 《Helvetica chimica acta》2011,94(7):1351-1358
A new furostanol saponin, sisalasaponin C ( 1 ), and a new spirostanol saponin, sisalasaponin D ( 2 ), were isolated from the fresh leaves of Agave sisalana, along with three other known steroidal saponins and two stilbenes. Their structures were identified as (3β,5α,6α,22α,25R)‐3,26‐bis[(β‐D ‐glucopyrano‐ syl)oxy]‐22‐hydroxyfurostan‐6‐yl β‐D ‐glucopyranoside ( 1 ), (3β,5α,25R)‐12‐oxospirostan‐3‐yl 6‐deoxy‐α‐L ‐mannopyranosyl‐(1→4)‐β‐D ‐glucopyranosyl‐(1→3)‐[β‐D ‐xylopyranosyl‐(1→3)‐β‐D ‐glucopyranosyl‐(1→2)]‐β‐D ‐glucopyranosyl‐(1→4)‐β‐D ‐galactopyranoside ( 2 ), (3β,5α,6α,22α,25R)‐22‐methoxyfurostane‐3,6,26‐triyl tris‐β‐D ‐glucopyranoside, cantalasaponin‐1, polianthoside D, (E)‐ and (Z)‐2,3,4′,5‐tetrahydroxystilbene 2‐O‐β‐D ‐glucopyranosides. The last three known compounds were isolated from the fresh leaves of Agavaceae for the first time. The structures of the new compounds were elucidated by detailed spectroscopic analysis, including 1D‐ and 2D‐NMR experiments, and chemical techniques. 相似文献
16.
17.
A New Furostanol Saponin from Dioscorea futshauensis 总被引:1,自引:0,他引:1
A new furostanol saponin presenting moderate bioacitivity of inducting morphological deformation of Pyricularia oryzae mycelia was isolated from Dioscorea futshauensis R.Kunth by bioacitivity-guided fractionation. The structure was established as 26-O-β-D-glucopyranosyl-3β,26-diol-23(S)-methoxyl-(25R)-furost-5,20(22)-diene-3-O-[α-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl(1→3)]-β-D-glucopyranoside on the basis of chemical evidencesand spectral analysis,especially by 2D-NMR techniques. 相似文献
18.
Pang X Kang L Yu H Zhao Y Xiong C Zhang J Shan J Ma B 《Journal of separation science》2012,35(12):1538-1550
An ultra-performance liquid chromatography coupled with a hybrid quadrupole time-of-flight tandem mass spectrometry method was established to rapidly identify and guide the isolation of target saponins from fenugreek seeds. Based on the online screening performance, totally forty-six furostanol saponins were detected and elucidated. Among them, twenty compounds were predicted to be new. To rapidly obtain new furostanol saponins from these seeds, a further phytochemical study was carried out under the guidance of the ultra-performance liquid chromatography coupled with a hybrid quadrupole time-of-flight tandem mass spectrometry. Finally, six new furostanol saponins, named as trigoneosides XIV (1), XV (2), XVI (3), XVIIa (4), XVIIb (5), and XIV (6), together with one known furostanol saponin, parvifloside (7), were rapidly obtained, and their definitive structures were determined by NMR and chemical evidence. 相似文献
19.
Bernadete Pereira da Silva Patricia Oliveira Campos Jose Paz Parente 《Chemistry of Natural Compounds》2006,42(3):316-321
A new bisdesmosidic furostanol saponin, along with a known spirostanol saponin, furcreastatin, were isolated from Furcraea gigantea Vent. (Agavaceae). The structure of the new saponin was elucidated as 3-[(O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1å 3)-O-[O-β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranosyl)oxy]-(3β, 5α, 25R)-26-(β-D-glucopyranosyloxy)-22-hydroxyfurost-12-one. The structural identification was performed using a combination of spectroscopic techniques and chemical conversions. Furcreastatin showed a powerful haemolytic effect in the in vitro assay, but the new bisdesmosidic furostanol saponin demonstrated only a significant inhibition of the capillary permeability activity. 相似文献
20.
Two furostanol saponins were obtained from the rhizomes of Tupistra chinensis Bak. Their structures were determined as 5beta-furost-delta(25(27))-en-1beta,2beta,3beta,4beta,5beta,7alpha,22xi,26-octaol-6-one-26-O-beta-D-glucopyranoside (1) and 5beta-furost-delta(25(27))-en-1beta,2beta,3beta,4beta,5beta,6beta,7alpha,22xi,26-nonaol-26-O-beta-D-glucopyranoside (2), on the basis of chemical and spectroscopic evidence. Both compounds displayed marked inhibitory action against NO production in rat abdomen macrophages induced by lipopolysaccharide (LPS) at 40 microg/mL. 相似文献