共查询到20条相似文献,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
7.
8.
9.
Shashikant U. Dighe Sushobhan Mukhopadhyay Shivalinga Kolle Dr. Sanjeev Kanojiya Sanjay Batra 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2015,127(37):11076-11080
An efficient NaNO2/I2‐mediated one‐pot transformation of Morita–Baylis–Hillman (MBH) acetates into alkyl 3‐nitro‐5‐(aryl/alkyl)isoxazole‐4‐carboxylates is described. In a cascade event, initial Michael addition of NaNO2 to the MBH acetate furnishes the allylnitro intermediate which undergoes I2‐catalyzed oxidative α‐C H nitration of the nitromethyl subunit followed by [3+2] cycloaddition to afford the title compounds. Structural elaborations of these highly substituted isoxazoles by SNAr reactions and hydrogenolysis allows access to useful products. 相似文献
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.