三种癌的铬、锰、锌、铜、铁、镁、钙含量

为进一步阐明癌组织与宏量、徽量元素的关系．用原子吸收光谱法测定胃癌、大肠癌、乳腺癌组织及其癌旁组织和同体正常组织中铬、锰、锌、铁、镁、铜和钙的含量．试找这些元素在癌、癌旁及其同体正常组织中的分布规律．测定结果；在胃癌组织中锌的含量比癌旁组织、同体正常组织少。铜的含量比正常组织多。其余五种元素的含量在这三个组织之间比较无明显差异；在大肠癌组织中锰、镁的音量比癌旁组织多．其他五种元素的含量在这三个组织之间比较，无明显差异；在乳腺癌组织中铬，锰和铁的含量比正常组织多。锌、镁、钙的含量比同体正常组织和癌旁组织多，铜的含量在这三个组织中比较无明显差异，总之，胃癌、大肠癌及乳腺癌组织及其癌旁组织和同体正常组织中。上述七种元素的音量是不同的。特别是在乳腺癌组织中除铜以外的六种元素的含量都比正常组织多．值得进一步研究．     

血清六种微量元素与胃癌的相关性

为研究胃癌患者血清微量元素与胃癌的相关性 ,探讨其在胃癌诊断中的应用 ,取甘肃省武威市 2 0例胃癌患者血清作为胃癌组 (C组 ) ,3 0例当地健康志愿者血清作为对照组 (N组 ) ,用电感耦合等离子体原子发射光谱仪 (ICP -AES)进行了 6种微量元素的测定 ,并将结果用SPSS软件作统计分析。结果表明 ,胃癌组血清微量元素值高于对照组的元素有Cu、Cu/Zn、Fe (P <0 0 1 ) :低于对照组的元素有Zn、Mn (P <0 0 5 )。经Logistic回归分析 ,进入方程的为Zn元素 (P<0 0 5 )。多种微量元素联合诊断胃癌的准确率为 87% ,误诊率为 8%。提示 ,甘肃省武威市胃癌患者血清中Cu、Cu/Zn、Fe的升高以及Zn、Mn的降低与胃癌的发生具有相关性。其中Zn与胃癌的发生关系最为密切 ,且Zn降低可能为胃癌发生的癌前因素。测定血清微量元素值可以作为早期诊断胃癌的一种工具。     

广西地区273例恶性肿瘤患者血清微量元素检测结果分析

为探讨血清微量元素与恶性肿瘤之间的关系,用化学比色法对273例恶性肿瘤患者和30例正常人血清中的铜、锌、铁、钙进行了检测。结果表明,恶性肿瘤患者血清钢和铜/锌比值明显高于正常人,而锌、铁、钙含量明显低于正常人,均有显著性差异,分别为P<0.001～P<0.05。提示:微量元素与恶性肿瘤的发生、发展密切相关,对恶性肿瘤的诊断、疗效及预后观察有重要价值。     

卵巢癌患者血清中铜、锌含量及铜/锌比值分析

为了解微量元素与卵巢癌的关系，对21例卵巢癌患者进行了血清Cu、Zn含量及Cu/Zn比值分析，并以30例健康女性为对照。结果表明，卵巢癌患者血清中Zn含量明显低于对照组(P＜0．01)，而Cu含量明显高于对照组(P＜0．01)，Cu/Zn比值也比对照组高。提示卵巢癌的发生与体内微量元素异常有关。     

Determination of trace elements in drinking tea by various analytical techniques

Tea has been one of the most popular simulating beverages which is both heavily produced and consumed in Taiwan. The determination of minor or trace elements in drinking tea and tea leaves is therefore important for estimating the daily intake of Taiwanese considered as a safety indicator. In order to accurately and precisely determine the concentrations of trace elements in samples, several analytical methods such as AAS, NAA and ICP-AES are suggested. This paper attempts to utilize all three methods to determine the concentrations of minor or trace elements in different types of tea leaves and the extracts percolated from them. The influence of fermentation processes on the concentration levels of minor or trace elements in tea samples is investigated. Because only free metal ions are bioavailable for the human body, it is necessary to determine their concentrations in drinking tea. The dissolution of trace elements in drinking tea is therefore studied by simulating the common Chinese style of tea percolation. Concentrations of thirteen elements including Zn, Mn, Ca, Cu, Ni, Al, K, Mg, Cd, Pb, Na, Co and Sc are determined.     

乳腺癌与血清微量元素关系的分析

经临床、病理、放射或CT检查确诊的22名乳腺癌患者。在放疗前后分析血清中Fe、Zn、Cu、Mn、Se、Cr、Co、Ni的含量。结果显示：1．乳腺癌患者与健康人比较Cu、Ni含量增加，而Fe、Zn含量减少；2．健康人锌与其他元素的比值与乳腺癌患者比较，Fe／Zn上升，而Cu／Zn下降；3．乳腺癌患者放疗后与放疗前比较，Zn、Fe、Se、Co含量降低，而Cu、Ni含量增加，因此放疗时要针对降低元素给予合理的补充。     

骨质疏松与微量元素

骨质疏松与某些矿物质的饮食摄取不足、过量或不平衡有关，但微量元素在骨质疏松的病理、诊断和治疗中也起着十分重要的作用。适量的Ｂ、Ｆ、Ｓｉ、Ｍｎ、Ｃｕ、Ｚｎ、Ｇｅ、Ｓｒ和Ｖ、Ｉ、Ｍｏ对骨骼的发育和代谢是必需的，但Ｐｂ、Ｃｄ、Ａｌ则可能是骨质疏松的危险因子。高尿锌可被用作骨质疏松的生物化学标记物，锶可代替钙用作骨矿化的标记物。临床实践表明，氟可明显增加骨质疏松患者的长轴骨密度和显著降低脊椎骨新骨折的发生     

胃癌和胃溃疡患者发中微量元素变化的研究

报道了湛江市胃癌患者发中微量元素的变化信息。胃癌患者与正常人相比，Zn、Zn/Cu、Mg、Ca显著降低（P＜0．05）；胃癌与胃溃疡患者相比，Zn、Zn/Cu、Mg均呈显著降低（P＜0．05）。因此，发中微量元素化学信息的变化，可作为本地区胃癌的辅助诊断和胃癌与胃溃疡的区别辅助诊断的依据之一。     

Analysis of trace elements in blood sera of breast cancer patients by particle induced X-ray emission

Trace elemental imbalance in human beings is postulated to exert action, directly or indirectly, on the carcinogenic process. The objective of this study was to evaluate the levels of trace elements in blood sera of breast cancer patients and analyze their alteration with respect to healthy controls. This work was also intended to establish the role played by the trace elements in carcinogenic process. Particle induced X-ray emission (PIXE) technique was used for trace elemental analysis of blood sera of breast cancer patients and healthy controls. The PIXE measurements were carried out using a 2.5?MeV collimated proton beam from the 3 MV Tandem Pelletron accelerator at Institute of Physics, Bhubaneswar, India. On comparing the trace elemental content in the sera of breast cancer patients with those of control subjects, significant variations were observed in the levels of most of the trace elements. The serum levels of almost all the elements except Fe and Cu were observed to be depressed in cancer patients with respect to normal subjects. However, this variation was significant only for Ti (P?<?0.00005), Cr (P?<?0.005), Mn (P?<?0.0005), Ni (P?<?0.01), Zn (P?<?0.000001), and Se (P?<?0.05). On the other hand, significant elevations were observed in serum Fe (P?<?0.05) and Cu (P?<?0.005) levels in cancer patients. The findings presented in this paper give guidelines for future study into the possible roles and interactions of essential trace elements in the breast carcinogenic process.     

益气活血中药复方对冠心病患者治疗前后微量元素的影响

为探讨益气活血复方调整冠心病患者微量元素达到平衡,纠正异常相关因素的作用机制,选择冠心病患者80例及健康人5 7例,分别测定了冠心病患者治疗前后和健康人血清中微量元素含量。结果表明,益气活血复方组和西药组治疗后,均见Se,Cr,Mn ,Mg ,Sr,Cu,K ,Na,Ca等微量元素含量明显升高,Zn含量,w(Zn) /w(Cu) ,Fe含量明显下降,P <0 0 5或P <0 0 1。虽然益气活血复方组和西药组治疗后,元素上升与下降的趋势基本相同,但益气活血复方对元素的影响更明显,尤其是Zn,Co含量,w(Zn) /w(Cu)下降,Cu ,Cr,Mn,Sr含量上升,差异极显著,P <0 0 1。提示益气活血复方能调节体内微量元素的平衡,恢复心肌功能,防治冠心病     

大肠癌与微量元素研究

对48例大肠癌患者手术前后血清和正常大肠组织与癌组织中微量元素测定、比较，发现大脑癌患者手术前后血清微量元素变化，除Cr、Mn有显著差异外均无显著差异，而癌瘤组织与正常大脑组织中Ca、Cd、Mn、Zn、Cu/Zn有明显差异，探讨了大肠癌发生的机理。大肠癌病因是复杂的，但与微量元素改变有一定关系，并指出，组织测定观察微量元素变化比血清测定观察更敏感。     

微量元素对老年人健康的作用与危害

介绍了微量元素的生理功能，微量元素与衰老，长寿和老年人冠心病，高血压，脑血管疾病，肿瘤，糖尿病等五种常见病的关系。还特别介绍了锌对人类健康的作用和铅对人类健康的危害。老年人体内有益的微量元素，如铁，锌，锰，铬，硒等比较缺乏，相反镍，铅，铝等有害的微量元素比较高。长寿老人头发中有益微量元素锰，钴，硒，铜，锌，铬等均有较高水平。人要长寿，必须维持体内微量元素的水平，微量元素过低或者过高应及时通过食疗或药物治疗进行调节。     

Groundwater Quality at the Huaibei Coalfield,China

The environmental and health impacts of trace elements are of great concern because of their toxicity, persistence, and bioavailability. Twenty-six groundwater samples were collected from the coal mining areas to evaluate water quality and potential environmental impact caused by mining activities. The physical/chemical properties and trace element concentrations (As, Cd, Cr, Cu, Pb, and Zn) were determined. The physical/chemical parameters and the concentrations of trace elements varied among the shallow and confined groundwater, which may indicate the absence of hydraulic interactions between the aquifers. The concentrations of trace elements in the mining areas are higher than at background monitoring sites, which suggests that the mining activities may lead to environmental and health impacts. Based on a health risk assessment, the low hazard quotients and cancer risk values in confined groundwater samples indicate that the chronic and cancer adverse effects due to trace elements are negligible. This study provides a comprehensive assessment of groundwater trace element impacts from coal mining in China and is useful for environmental management.     

成都市学龄前儿童末梢血微量元素检测结果的分析

为探讨成都市学龄前儿童末梢血微量元素的缺乏现状及其含量与年龄和性别的关系,利用BH 5100型原子吸收光谱仪对23 932例学龄前儿童末梢血中铜、锌、钙、镁和铁元素进行了检测,用SPSS 16.0做了统计分析.结果表明,所测学龄前儿童末梢血铁、锌元素缺乏严重;铜、锌、钙和铁元素含量在年龄上呈现一定变化规律,铜元素在男女...     

西安市学龄前儿童末梢血微量元素检测结果分析

为探讨西安市学龄前儿童末梢血微量元素现状及其含量与年龄及性别的关系,对2 350例学龄前儿童末梢血中铜、锌、钙、镁、铁5种元素进行了测定,用SPSS 16.0做统计分析.结果表明,受检儿童末梢血中锌、钙、铁缺乏严重,铜和锌含量在年龄上具变化规律,且铜在性别间存在显著差异.提示应充分认识微量元素对儿童健康的重要性,定期对...     

300例头发微量元素结果分析

为寻找病因、了解婴幼儿体内微量元素缺乏状态与某些疾病的关系,分析了300例发样中的锌、铁、铜、钙、锰、铅含量,结果显示婴幼儿病态下微量元素缺乏较为普遍,是婴幼儿食欲低下、生长发育迟缓、佝偻病、贫血症、多动症的主要病因,反复上呼吸道感染、腹痛、头痛也与体内微量元素浓度有关。     

青海枸杞子中微量元素含量的测定

测定了青海枸杞子中锌、铜、锰、铅、砷、铁、硒等微量元素的含量。结果表明,青海枸杞子中含锌18.65μg/g,铜15.62μg/g,锰6.24μg/g,铅1.03μg/g,砷0.24μg/g,铁19.68μg/g,硒2.15μg/g,人体必需微量元素含量丰富,是枸杞具有极为重要的保健、防病、治病功能的重要原因之一。     

探讨维甲酸诱导小鼠肝癌细胞凋亡血清微量元素的变化

为探讨维甲酸诱导小鼠肝癌细胞凋亡的血清微量元素的变化,收集30例实验组BALBC小鼠血清标品,应用等离子体发射光谱仪测定了se、zn、cu、Fe、Ca、Mg含量。结果表明,血清微量元素含量测定,维甲酸组Zn、Mg含量低于对照组,se、cu、Fe、ca含量和对照组比差异无显著性（P〉0．05）。提示维甲酸诱导小鼠肝细胞凋亡,血清微量元素含量变化不大与肝癌发生、靠展无相关件．     

列车员发中微量元素的测定及与消化疾病关系的研究

分析了人体内微量元素的含量及有消化系统疾患者的微量元素变化。最枕后根部头发进行湿法消化,用原子吸收仪测定K、Ca、Fe、Na、Zn、Mg、Mn含量男女间差异有显著性,其中女性K低于男性,其余四种元素含量女性高于男性。男列车员有消化系统疾患者与对照组比较,Zn减少,Mn增加,差异有显著性。可认为列车员职业不影响人体内微量元素水平。     

320例儿童手指血微量元素结果分析

为对门诊健康体检的320例0～10岁儿童手指血的微量元素及其相关情况进行分析,用原子吸收光谱仪测定了其指血的铜、锌、钙、镁、铁的含量。结果表明,锌缺乏随着年龄的增加逐渐减少,铁、钙缺乏随着年龄的增加而逐渐增多。提示孝感市1个月-10岁的儿童存在一定的微量元素缺乏,应注意均衡饮食,加强锌、铁、钙的补充及吸收。