Magnetic N‐doped mesoporous carbon as an adsorbent for the magnetic solid‐phase extraction of phthalate esters from soft drinks

A new kind of magnetic N‐doped mesoporous carbon was prepared by the one‐step carbonization of a hybrid precursor (glucose, melamine, and iron chloride) in a N₂ atmosphere with a eutectic salt (KCl/ZnCl₂) as the porogen. The obtained magnetic N‐doped mesoporous carbon showed excellent characteristics, such as strong magnetic response, high surface area, large pore volume, and abundant π‐electron system, which endow it with a great potential as a magnetic solid‐phase extraction adsorbent. To evaluate its adsorption performance, the magnetic N‐doped mesoporous carbon was used for the extraction of three phthalate esters from soft drink samples followed by high‐performance liquid chromatographic analysis. Under the optimum conditions, the developed method showed a good linearity (1.0–120.0 ng/mL), low limit of detection (0.1–0.3 ng/mL, S/N = 3), and good recoveries (83.2–119.0%) in soft drink samples. The results indicated that the magnetic N‐doped mesoporous carbon has an excellent adsorption capacity for phthalate esters and the present method is simple, accurate, and highly efficient for the extraction and determination of phthalate esters in complex matrix samples.     

Phytic acid induced three‐dimensional graphene for the enrichment of phthalate esters from bottled water and sports beverage samples

A three‐dimensional graphene was synthesized through a hydrothermal reaction of graphene oxide with phytic acid. The microstructure and morphology of the phytic acid induced three‐dimensional graphene were investigated by nitrogen adsorption–desorption isotherms, scanning electron microscopy, and transmission electron microscopy. With a large surface area and three‐dimensional structure, the graphene was used as the solid‐phase extraction adsorbent for the extraction of phthalate esters from bottled water and sports beverage samples before high‐performance liquid chromatographic analysis. The results indicated that the graphene was efficient for the solid‐phase extraction of phthalate esters. The limits of detection (S/N = 3) of the method for the analytes were 0.02–0.03 ng/mL for the water samples and 0.03–0.15 ng/mL for the sports beverage sample. The limits of quantitation (S/N = 9) for the analytes were 0.06–0.09 ng/mL for water samples and 0.09–0.45 ng/mL for sports beverage sample. The calibration curves for the phthalate esters by the method had a good linearity from 0.1 to 80.0 ng/mL with correlation coefficients larger than 0.9997. The recoveries of the analytes for the method fell in the range of 86.7–116.2% with the relative standard deviations between 1.5 and 6.8%.     

Magnetic spherical carbon as an efficient adsorbent for the magnetic extraction of phthalate esters from lake water and milk samples

Magnetic spherical carbon was synthesized by a facile hydrothermal carbonization procedure with biomass glucose as the carbon precursor and nanoclusters iron colloid as magnetic precursor. The textures of the as‐prepared magnetic spherical carbon were characterized by nitrogen adsorption–desorption isotherms, X‐ray diffraction, transmission electron microscopy, scanning electron microscopy and vibration sample magnetometry. Results indicated that the magnetic spherical carbon possessed high surface area as well as strong magnetism, which endows the material with good adsorption capability and easy separation properties. To assess its absorption performance, the magnetic spherical carbon was employed as adsorbent for the extraction and preconcentration of phthalate esters from lake water and milk samples before high‐performance liquid chromatographic analysis. Some key parameters that could influence the enrichment efficiency were investigated. Under the optimum conditions, a good linearity was achieved with the linear correlation coefficients higher than 0.9973. The limits of detection (S/N = 3) were 0.05–0.08 ng/mL for lake water and 0.1–0.2 ng/mL for milk samples. The recoveries of the analytes for the method were in the range 80.1–112.6%.     

Porous carbon derived from a metal–organic framework as an efficient adsorbent for the solid‐phase extraction of phthalate esters

A porous carbon designated as MOF‐5‐C was prepared by directly carbonizing a metal–organic framework (MOF‐5). The morphology and microstructure of MOF‐5‐C were characterized by scanning electron microscopy, N₂ adsorption, and powder X‐ray diffraction. The MOF‐5‐C retained the original porous structures of MOF‐5, and showed a high Brunauer–Emmett–Teller surface area (1808 m² g^?1) and large pore volume (3.05 cm³ g^?1). To evaluate its adsorption performance, the MOF‐5‐C was used as an adsorbent for the solid‐phase extraction of four phthalate esters from bottled water, peach juice, and soft drink samples followed by high‐performance liquid chromatographic analysis. Several parameters that could affect the extraction efficiencies were investigated. Under the optimum conditions, a good linearity was achieved in the concentration range of 0.1–50.0 ng mL^?1 for bottled water sample and 0.2–50.0 ng mL^?1 for peach juice and soft drink samples. The limits of detection of the method (S/N = 3) were 0.02 ng mL^?1 for bottled water sample, and 0.04–0.05 ng mL^?1 for peach juice and soft drink samples. The results indicated that the MOF‐5‐C exhibited an excellent adsorption capability for trace levels of phthalate esters, and it could be a promising adsorbent for the preconcentration of other organic compounds.     

Application of magnetic graphitic carbon nitride nanocomposites for the solid‐phase extraction of phthalate esters in water samples

Magnetic graphitic carbon nitride nanocomposites were successfully prepared in situ and used to develop a highly sensitive magnetic solid‐phase extraction method for the preconcentration of phthalate esters such as di‐n‐butyl phthalate, butyl phthalate, dihexyl phthalate, and di‐(2‐ethyl hexyl) phthalate from water. The adsorption and desorption of the phthalate esters on magnetic graphitic carbon nitride nanocomposites were investigated and the parameters affecting the partition of the phthalate esters, such as adsorption, desorption, recovery, were assessed. Under the optimized conditions, the proposed method showed excellent sensitivity with limits of detection (S/N = 3) in the range of 0.05–0.1 μg/L and precision in the range of 1.1–2.6% (n = 5). This method was successfully applied to the analysis of real water samples, and good spiked recoveries over the range of 79.4–99.4% were obtained. This research provides a possibility to apply this nanocomposite for adsorption, preconcentration, or even removal of various carbon‐based ring or hydrophobic pollutants.     

Solid‐phase extraction based on chloromethylated polystyrene magnetic nanospheres followed by gas chromatography with mass spectrometry to determine phthalate esters in beverages

An ultrasound‐assisted magnetic solid‐phase extraction procedure with chloromethylated polystyrene‐coated Fe₃O₄ nanospheres as magnetic adsorbents has been developed to determine eight phthalate esters (bis(4‐methyl‐2‐pentyl) phthalate, dipentyl phthalate, dihexyl phthalate, benzyl butyl phthalate, bis(2‐butoxyethyl) phthalate, dicyclohexyl phthalate, di‐n‐octyl phthalate, and dinonyl phthalate) simultaneously in beverage samples, in combination with gas chromatography coupled to tandem mass spectrometry for the first time. Several factors related to magnetic solid‐phase extraction efficiencies, such as amount of adsorbent, extracting time, ionic strength, and desorption conditions were investigated. The enrichment factors of the method for the eight analytes were over 2482. A good linearity was observed in the range of 10–500 ng/L for bis(2‐butoxyethyl) phthalate and 2–500 ng/L for the other phthalate esters with correlation coefficients ranging from 0.9980 to 0.9998. The limits of detection and quantification for the eight phthalate esters were in the range of 0.20–2.90 and 0.67–9.67 ng/L, respectively. The mean recoveries at three spiked levels were 75.8–117.7%, the coefficients of variations were <11.6%. The proposed method was demonstrated to be a simple and efficient technique for the trace analysis of the phthalate esters in beverage samples.     

New application of chitosan‐grafted polyaniline in dispersive solid‐phase extraction for the separation and determination of phthalate esters in milk using high‐performance liquid chromatography

Chitosan‐grafted polyaniline was synthesized and applied as a sorbent for the preconcentration of phthalate esters in dispersive solid‐phase extraction. By coupling dispersive solid‐phase extraction with high‐performance liquid chromatography and response surface methodology (central composite design), a reliable, sensitive, and cost‐effective method for simultaneous determination of phthalate esters including dimethyl phthalate, di‐n‐butyl phthalate, and di(2‐ethylhexyl)phthalate was developed. The morphology of sorbent had been studied by scanning electron microscopy and its chemical structure confirmed by Fourier transform infrared spectroscopy. Under optimum condition, good linearity was observed in the range of 5.0–5000.0 ng/mL. The limits of detection (S/N = 3) and limits of quantification (S/N = 10) were 0.1–0.3 and 0.3–1 ng/mL, respectively. The relative standard deviations were less than 8.8%. Finally, this procedure was employed for extraction of trace amounts of phthalic acid esters in milk samples, the relative recoveries ranged from 82 to 103%.     

Determination of phthalates in beverages using multiwalled carbon nanotubes dispersive solid‐phase extraction before HPLC–MS

A microdispersive solid‐phase extraction method has been developed using multiwalled carbon nanotubes of 110–170 nm diameter and 5–9 μm length for the extraction of a group of nine phthalic acid esters (i.e., bis(2‐methoxyethyl) phthalate, bis‐2‐ethoxyethyl phthalate, dipropyl phthalate, butylbenzyl phthalate, bis‐2‐n‐butoxyethyl phthalate, bis‐isopentyl phthalate, bis‐n‐pentyl phthalate, dicyclohexyl phthalate, and di‐n‐octyl phthalate) from tap water as well as from different beverages commercialized in plastic bottles (mineral water, lemon‐ and apple‐flavored mineral water, and an isotonic drink). Determination was carried out by high‐performance liquid chromatography coupled to mass spectrometry. The extraction procedure was optimized following a step‐by‐step approach, being the optimum extraction conditions: 50 mL of each sample at pH 6.0, 80 mg of sorbent, and 25 mL of acetonitrile as elution solvent. To validate the methodology, matrix‐matched calibration and a recovery study were developed, obtaining determination coefficients >0.9906 and absolute recovery values between 70 and 117% (with relative standard deviations < 17%) in all cases. The limits of quantification of the method were between 0.173 and 1.45 μg/L. After the evaluation of the matrix effects, real samples were also analyzed, finding butylbenzyl phthalate in all samples (except in apple‐flavored mineral water), though at concentrations below its limit of quantification of the method.     

Magnetic porous carbon derived from Co‐doped metal–organic frameworks for the magnetic solid‐phase extraction of endocrine disrupting chemicals

Metal–organic frameworks‐5 (MOF‐5) was explored as a template to prepare porous carbon due to its high surface area, large pore volume, and permanent nanoscale porosity. Magnetic porous carbon, Co@MOF‐5‐C, was fabricated by the one‐step direct carbonization of Co‐doped MOF‐5. After carbonization, the magnetic cobalt nanoparticles are well dispersed in the porous carbon matrix, and Co@MOF‐5‐C displays strong magnetism (with the saturation magnetization intensity of 70.17emu/g), high‐specific surface area, and large pore volume. To evaluate its extraction performance, the Co@MOF‐5‐C was applied as an adsorbent for the magnetic solid‐phase extraction of endocrine disrupting chemicals, followed by their analysis with high‐performance liquid chromatography. The developed method exhibits a good linear response in the range of 0.5–100 ng/mL for pond water and 1.0–100 ng/mL for juice samples. The limits of detection (S/N  = 3) for the analytes were in the range of 0.1–0.2 ng/mL.     

A porous carbon derived from amino‐functionalized material of Institut Lavoisier as a solid‐phase microextraction fiber coating for the extraction of phthalate esters from tea

In this work, a porous carbon derived from amino‐functionalized material of Institut Lavoisier (C‐NH₂‐MIL‐125) was prepared and coated onto a stainless‐steel wire through sol–gel technique. The coated fiber was used for the solid‐phase microextraction of trace levels of phthalate esters (diallyl phthalate, di‐iso‐butyl ortho‐phthalate, di‐n‐butyl ortho‐phthalate, benzyl‐n‐butyl ortho‐phthalate, and bis(2‐ethylhexy) ortho‐phthalate) from tea beverage samples before gas chromatography with mass spectrometric analysis. Several experimental parameters that could influence the extraction efficiency such as extraction time, extraction temperature, sample pH, sample salinity, stirring rate, desorption temperature and desorption time, were investigated. Under the optimal conditions, the linearity existed in the range of 0.05–30.00 μg/L for green jasmine tea beverage samples, and 0.10–30.00 μg/L for honey jasmine tea beverage samples, with the correlation coefficients (r) ranging from 0.9939 to 0.9981. The limits of detection of the analytes for the method were 2.0–3.0 ng/L for green jasmine tea beverage sample, and 4.0–5.0 ng/L for honey jasmine tea beverage sample, depending on the compounds. The recoveries of the analytes for the spiked samples were in the range of 82.0–106.0%, and the precision, expressed as the relative standard deviations, was less than 11.1%.     

Magnetic porous carbon derived from a metal–organic framework as a magnetic solid‐phase extraction adsorbent for the extraction of sex hormones from water and human urine

An iron‐embedded porous carbon material (MIL‐53‐C) was fabricated by the direct carbonization of MIL‐53. The MIL‐53‐C possesses a high surface area and good magnetic behavior. The structure, morphology, magnetic property, and porosity of the MIL‐53‐C were studied by scanning electron microscopy, transmission electron microscopy, vibrating sample magnetometry, and N₂ adsorption. With the use of MIL‐53‐C as the magnetic solid‐phase extraction adsorbent, a simple and efficient method was developed for the magnetic solid‐phase extraction of three hormones from water and human urine samples before high‐performance liquid chromatography with UV detection. The developed method exhibits a good linear response in the range of 0.02–100 ng/mL for water and 0.5–100 ng/mL for human urine samples , respectively. The limit of detection (S/N = 3) for the analytes was 0.005–0.01 ng/mL for water sample and 0.1–0.3 ng/mL for human urine sample. The limit of quantification (S/N = 10) of the analytes were in the range of 0.015–0.030 and 0.3–0.9 ng/mL, respectively.     

Centrifugeless ultrasound‐assisted emulsification microextraction based on salting‐out phenomenon followed by high‐performance liquid chromatography for the simple determination of phthalate esters in aqueous samples

A fast, sensitive, and centrifugeless ultrasound‐assisted emulsification microextraction followed by a high‐performance liquid chromatography method is developed for the determination of some phthalate esters in aqueous samples. In this method, a simple approach is followed to eliminate the centrifugation step in dispersive liquid–liquid microextraction using an organic solvent whose melting point is near the ambient temperature, consumption of the extracting solvent is efficiently reduced, and the overall extraction time was found to be only 7 min. The variables affecting the method are optimized. Under the optimal experimental conditions (75 μL of 1‐undecanol, a flow rate of 2.0 mL/min, and an ultrasound irradiation of 1 min), the proposed method exhibits good preconcentration factors (52–97), low limits of detection (1.0–5.0 ng/mL), and linearities in the range of 5–1500 ng/mL (r ² ≥ 0.995). Finally, the method is successfully applied to the analysis of phthalate esters in the drinking and river water samples. To study the probable release of the phthalate esters from a polyethylene container into boiling water, the boiling water exposed to the polyethylene container was analyzed by the proposed method.     

Core‐shell structured magnetic mesoporous carbon nanospheres derived from metal‐polyphenol coordination polymer‐coated Fe3O4 and its application in the enrichment of phthalates from water samples

In this work, core‐shell structured magnetic mesoporous carbon nanospheres were fabricated from the carbonization of metal‐polyphenol coordination polymer‐coated Fe₃O₄ nanoparticles. The preparation method is simple, fast, versatile, and easy to scale up. Magnetic mesoporous carbon nanospheres exhibit a high specific surface area, high superparamagnetism, and high adsorption efficiencies for phthalates. Four phthalates were extracted from aqueous solutions by using magnetic mesoporous carbon nanospheres via magnetic solid phase extraction. Subsequent analysis was performed by using high‐performance liquid chromatography with ultraviolet detection. The analytical method has good linearity in the concentration range of 1–200 ng/mL for diethyl phthalate, diisobutyl phthalate, and dicyclohexyl phthalate, and 3–200 ng/mL for dipropyl phthalate. The limits of detection were in the range of 0.10–0.62 ng/mL. Compared with previous methods, this method has a lower detection limit, wider linearity range, and faster adsorption and desorption rates. The results indicate that magnetic mesoporous carbon nanospheres are suitable for the enrichment of hydrophobic substances from aqueous solutions.     

Determination of phthalate esters from environmental water samples by micro‐solid‐phase extraction using TiO2 nanotube arrays before high‐performance liquid chromatography

We describe a highly sensitive micro‐solid‐phase extraction method for the pre‐concentration of six phthalate esters utilizing a TiO₂ nanotube array coupled to high‐performance liquid chromatography with a variable‐wavelength ultraviolet visible detector. The selected phthalate esters included dimethyl phthalate, diethyl phthalate, dibutyl phthalate, butyl benzyl phthalate, bis(2‐ethylhexyl)phthalate and dioctyl phthalate. The factors that would affect the enrichment, such as desorption solvent, sample pH, salting‐out effect, extraction time and desorption time, were optimized. Under the optimum conditions, the linear range of the proposed method was 0.3–200 μg/L. The limits of detection were 0.04–0.2 μg/L (S/N = 3). The proposed method was successfully applied to the determination of six phthalate esters in water samples and satisfied spiked recoveries were achieved. These results indicated that the proposed method was appropriate for the determination of trace phthalate esters in environmental water samples.     

Microwave‐assisted preparation of poly(ionic liquids)‐modified polystyrene magnetic nanospheres for phthalate esters extraction from beverages

The fabrication of novel poly(ionic liquids)‐modified polystyrene (PSt) magnetic nanospheres (PILs‐PMNPs) by a one‐pot miniemulsion copolymerization reaction was achieved through an efficient microwave‐assisted synthesis method. The morphology, structure, and magnetic behavior of the as‐prepared magnetic materials were characterized by using transmission electron microscopy, vibrating sample magnetometry, etc. The magnetic materials were utilized as sorbents for the extraction of phthalate esters (PAEs) from beverage samples followed by high‐performance ultrafast liquid chromatography analysis. Significant extraction parameters that could affect the extraction efficiencies were investigated particularly. Under optimum conditions, good linearity was obtained in the concentration range of 0.5–50 (dimethyl phthalate), 0.3–50 (diethyl phthalate), 0.2–50 (butyl benzyl phthalate), and 0.4–50 μg/L (di‐n‐butyl phthalate), with correlation coefficients R ² > 0.9989. Limits of detection were in the range 125–350 pg. The proposed method was successfully applied to determine PAEs from beverage samples with satisfactory recovery ranging from 77.8 to 102.1% and relative standard deviations ranging from 3.7 to 8.4%. Comparisons of extraction efficiency with PSt‐modified MNPs as sorbents were performed. The results demonstrated that PILs‐PMNPs possessed an excellent adsorption capability toward the trace PAE analytes.     

Simple and rapid determination of phthalates using microextraction by packed sorbent and gas chromatography with mass spectrometry quantification in cold drink and cosmetic samples

A simple and rapid method using microextraction by packed sorbent coupled with gas chromatography and mass spectrometry has been developed for the analysis of five phthalates, namely, diethyl phthalate, benzyl‐n‐butyl phthalate, dicyclohexyl phthalate, di‐n‐butyl phthalate, and di‐n‐propyl phthalate, in cold drink and cosmetic samples. The various parameters that influence the microextraction by packed sorbent performance such as extraction cycle (extract–discard), type and amount of solvent, washing solvent, and pH have been studied. The optimal conditions of microextraction using C₁₈ as the packed sorbent were 15 extraction cycles with water as washing solvent and 3 × 10 μL of ethyl acetate as the eluting solvent. Chromatographic separation was also optimized for injection temperature, flow rate, ion source, interface temperature, column temperature gradient and mass spectrometry was evaluated using the scan and selected ion monitoring data acquisition mode. Satisfactory results were obtained in terms of linearity with R² >0.9992 within the established concentration range. The limit of detection was 0.003–0.015 ng/mL, and the limit of quantification was 0.009–0.049 ng/mL. The recoveries were in the range of 92.35–98.90% for cold drink, 88.23–169.20% for perfume, and 88.90–184.40% for cream. Analysis by microextraction by packed sorbent promises to be a rapid method for the determination of these phthalates in cold drink and cosmetic samples, reducing the amount of sample, solvent, time and cost.     

Hollow fiber stir bar sorptive extraction for determination of phthalic acid esters in environmental and biological matrices

The purpose of this paper is to introduce a novel hollow fiber stir bar sorptive extraction for collecting and determining of phthalic acid esters in environmental and biological matrices. Shell–core ZrO₂/SiO₂ composite microspheres and porous C₁₈ silica microspheres were compared as the sorbents, which were loaded in the lumen of a microporous hollow fiber membrane. A thin stainless‐steel wire was also inside of the hollow fiber membrane acting as the magnetic stirrer, thus affording the procedures like stir bar sorptive extraction to perform the active trapping of the analytes. Variables affecting the extraction (salt addition and pH of samples, extraction temperature, and time) and desorption (microwave time and eluted solvents) have been optimized. Under the optimal conditions, good linearity (r > 0.9968) of all calibration curves was obtained in validation experiments. And the limits of quantification ranged from 0.01 to 1000 ng/mL. The recoveries in different matrices were in the range of 64.90–112.60% with relative standard deviations less than 8.60%. The present work demonstrated the applicability of the developed method for the determination of phthalic acid esters in environmental and biological sample, allowing the selective extraction of phthalate esters in complex samples with low consumption of organic solvents and no sample clean‐up.     

Utilization of homogeneous liquid–liquid extraction followed by HPLC-UV as a sensitive method for the extraction and determination of phthalate esters in environmental water samples

A simple and sensitive method for the extraction of four phthalate esters including dimethyl phthalate (DMP), diethyl phthalate (DEP), benzyl butyl phthalate (BBP) and di-n-butyl phthalate (DBP) as well as their determination in water samples was developed using homogeneous liquid–liquid extraction (HLLE) and HPLC-UV. The extraction method is based on the phase separation phenomenon by the salt addition to the ternary solvent system. The extraction parameters such as type and volume of extracting and consolute solvent, concentration of salt, pH of sample and extraction time were optimized. Under the optimal conditions (extraction solvent: 100?µL CHCl₃; consolute solvent: 2.0?mL methanol; NaCl 15% (w/v) and pH of sample: 6.5) extraction recovery was in the range of 92–102%. Linearity was observed in the range of 0.5–300?µg?L^?1 for DEP and 0.6–300?µg?L^?1 for DMP, BBP and DBP. Correlation coefficients (r ²), limits of detection (LODs) and relative standard deviations (RSDs) were in the ranges of 0.9976–0.9993, 0.18–0.25 and 1.5–4.8%, respectively. The method was successfully applied for the preconcentration and determination of these phthalate esters in the several environmental water samples.     

Extraction of ochratoxin A in red wine with dopamine‐coated magnetic multi‐walled carbon nanotubes

A new, rapid, green, and cost‐effective magnetic solid‐phase extraction of ochratoxin A from red wine samples was developed using polydopamine‐coated magnetic multi‐walled carbon nanotubes as the absorbent. The polydopamine‐coated magnetic multi‐walled carbon nanotubes were fabricated with magnetic multi‐walled carbon nanotubes and dopamine by an in situ oxidative self‐polymerization approach. Transmission electron microscopy, dynamic light scattering, X‐ray photoelectron spectroscopy and vibrating sample magnetometry were used to characterize the absorbents. Ochratoxin A was quantified with high‐performance liquid chromatography coupled with fluorescence detection, with excitation and emission wavelengths of 338 and 455 nm, respectively. The conditions affecting the magnetic solid‐phase extraction procedure, such as pH, extraction solution, extraction time, absorbent amount, desorption solution and desorption time were investigated to obtain the optimal extraction conditions. Under the optimized conditions, the extraction recovery was 91.8–104.5% for ochratoxin A. A linear calibration curve was obtained in the range of 0.1–2.0 ng/mL. The limit of detection was 0.07 ng/mL, and the limit of quantitation was 0.21 ng/mL. The recoveries of ochratoxin A for spiked red wine sample ranged from 95.65 to 100.65% with relative standard deviation less than 8%. The polydopamine‐coated magnetic multi‐walled carbon nanotubes showed a high affinity toward ochratoxin A, allowing selective extraction and quantification of ochratoxin A from complex sample matrixes.     

Synthesis of molecularly imprinted polymers by atom transfer radical polymerization for the solid‐phase extraction of phthalate esters in edible oil

Novel molecularly imprinted polymers of phthalate esters were prepared by atom transfer radical polymerization using methyl methacrylate as functional monomer, cyclohexanone as solvent, cuprous chloride as catalyst, 1‐chlorine‐1‐ethyl benzene as initiator and 2,2‐bipyridyl as cross‐linker in the mixture of methanol and water (1:1, v/v). The effect of reaction conditions such as monomer ratio and template on the adsorption properties was investigated. The optimum condition was obtained by an orthogonal experiment. The obtained polymers were characterized using scanning electron microscopy. The binding property was studied with both static and dynamic methods. Results showed that the polymers exhibited excellent recognition capacity and outstanding selectivity for ten phthalate esters. Factors affecting the extraction efficiency of the molecularly imprinted solid‐phase extraction were systematically investigated. An analytical method based on the molecularly imprinted coupled with gas chromatography and flame ionization detection was successfully developed for the simultaneous determination of ten phthalate esters from edible oil. The method detection limits were 0.10–0.25 μg/mL, and the recoveries of spiked samples were 82.5–101.4% with relative standard deviations of 1.24–5.37% (n = 6).