Enzymatic synthesis of multiple tritium-labeled nucleosides and nucleotides from nitrogen bases and ribose

A wide range of highly active nucleotides containing tritium labels in the heterocycle nucleus and ribose residue has been synthesized with the aid of an enzyme preparation fromE. coli, starting from tritium labeled nitrogen bases and ribose. In individual cases, the complex enzyme preparation was modified by the addition of nucleotide kinases or phosphatases.V. G. Khlopin Radium Institute and Biological Scientific Research Institute, A. A. Zhdanov Leningrad State University. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 258–264, March–April, 1988.     

Structure of terdeline

A new alkaloid which has been called terdeline has been isolated from the epigeal part ofDelphinium ternatum. Its structure has been demonstrated on the basis of spectral characteristics and the preparation of a demethylene derivative, and also by direct passage from eldelidine to terdeline.Abu Ali Ibn Sina [Avicenna] Tadzhik State Medical Institute, Dushanbe. Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 396–399, May–June, 1988.     

Berberis alkaloids. XV. Structure of bargustanine

Bargustanine (I), belonging to a new type of isoquinoline alkaloids, has been isolated from the phenolic fraction of the total alkaloids from the roots ofBerberis vulgaris L. Its structure has been established by chemical and spectral methods.Institute of Chemistry of Plant Substances, Uzbekistan Republic Academy of Sciences, Tashkent. Andizhan State Medical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 44–47, January–February, 1993.     

Berberis alkaloids. XVII. Investigation of the alkaloids of Berberis heteropoda

The alkaloid composition of young shoots and leaves ofBerberis heteropoda Schrenk has been studied. In addition to known alkaloids, two new ones have been isolated — N-methyldihydroberberine and 8-oxoberberrubine, the structures of which were established by chemical transformations and a study of spectral properties. Of known alkaloids, berbamunine, aromoline, glaucine, thalicmidine, isocorydine, and reticuline have been found in this plant for the first time. Pseudopalmitine and laudanosine have been found for the first time in plants of the genusBerberis.Andizhan State Medical Institute. Institute of the Chemistry of Plant Substances of Uzbek Republic Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 53–59, January–February, 1993.     

Flavonoids of Bidens tripartita. III

Summary It has been established that substance 4, isolated previously fromBidens tripartita, is (R-2)isookanin 7-O--D-glucopyranoside [(R-2)flavanomarein]. The compound isolated is a new one for the genusBidens L.Khar'kov State Pharmaceutical Institute. Khar'kov Scientific-Research Institute of Pharmaceutical Chemistry. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 144–147, March–April, 1975.     

Esters of Ferula karakalensis. Structure and stereochemistry of karaferin and karaferinin

Two new guaiane esters — karaferin and karaferinin — have been isolated fromFerula karakalensis, and their structures and stereochemistry have been established. It has been shown that theFerula sesquiterpene alcohols angrendiol, ugamdiol, and karaferol are biogenetically interconnected and are products of a single chain of the biogenesis of terpenoids in plants.Institute of Chemistry of Plant Substances, Uzbekistan Republic Academy of Sciences, Tashkent; Botanical Garden of Moscow State University. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 227–231, March–April, 1993.     

Berberis alkaloids. XXIII. Structure of turcberine

Berberine, magnoflorine, palmatine, columbamine, jatrorhizine, epiberberine, berbamine, O-methylisothalicberine, armepavine, corypalline, glaucine, and corydine and the new alkaloid turcberine have been isolated fromBerberis turcomanica Kar., and the structure of turcberine has been established. Apart from berberine, this is the first time that any of these alkaloids have been isolated from this species of barberry, while this is the first time that corydine and armepavine have been isolated from the genusBerberis.Institute of Chemistry of Plant Substances, Uzbekistan Republic Academy of Sciences. Tashkent. Andizhan State Medical Institute. Translated from Khimiya Prirodnykh Soedeninii, No. 1, pp. 77–81, January–February, 1993.     

Berberis alkaloids. XXII. Interbrinine and intebrimine — New alkaloids from Berberis integerrima

The known alkaloids reticuline, isoboldine, isocorydine, glaucine, armepavine, oxyacanthine, and heliamine and the new alkaloids intebrinine and intebrimine have been isolated from the total alkaloids of the leaves ofBerberis integerrima, and structures have been proposed for the latter two on the basis of spectral characteristics and independent synthesis.Andizhan State Medical Institute. Institute of the Chemistry of Plant Substances, Uzbekistan Republic Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedeninii, No. 1, pp. 70–73, January–February, 1993.     

Phytochemical study of Centaurea cyanus

Flavonoid aglycons (quercetin, kaempferol, isorhamnetin, apigenin, luteolin, hispidulin) and their glycosides, and caffeic, chlorogenic, neochlorogenic, and isochlorogenic acids have been isolated from the epigeal part of theCentaurea cyanus L. and have been identified, and ten amino acids have also been identified.Kursk State Medical Institute. Translated from Khimiya Prirodynkh Soedinenii, No. 6, pp. 792–795, November–December, 1988.     

Berberis alkaloids. XVI. Structure of berpodine

The alkaloid composition of young shoots ofBerberis heteropoda has been studied. Together with known alkaloids, we have isolated the new dimeric base berpodine and have established its structure by a study of spectral characteristics and by chemical transformations. The known alkaloid isotetrandrine has also been isolated from this plant, for the first time.Institute of Chemistry of Plant Substances Uzbekistan Republic Academy of Sciences, Tashkent. Andizhan State Medical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 264–267, March–April, 1993.     

Flavonoid compounds of Scutellaria przewalskii

Conclusions The epigeal part ofScutellaria przewalskii has been shown to contain apigenin, luteolin, scutellarein, dinatin, hispidulin, pectolinarigenin; the 7-glucosides and 7-glucuronides of apigenin, luteolin, scutellarein, and dinatin; and also the 7-glucobiosides of scutellarein, dinatin, and hispidulin; and these substances have been isolated. It has been established that the glucuronides of the flavonoids are present in the salt form.Institute of Organic Chemistry, Academy of Sciences of the Kirgiz SSR. Khar'kov Scientific-Research Institute of Pharmaceutical Chemistry. Zaporozhe State Pharmaceutical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 534–539, September–October, 1970.     

Polysaccharides of Matricaria chamomilla I. Monosaccharide composition of the polysaccharide complex

Conclusions 1. A polysaccharide has been isolated from the inflorescences ofMatricaria chamomilla L. It has been established that it is composed of D-galacturonic acid (45%), D-galactose (12.2%), D-glucose (2.3%), L-rhamnose (5.3%), L-arabinose (10.2%), and D-xylose (20.8%).2. The information obtained permits the polysaccharide of the camomile to be assigned to the class of pectin substances.Academician I. P. Pavlov Ryazan' State Medical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 137–141, March–April, 1974.     

New terpenoids of the essential oil of Ledum palustre

The structures of two new natural compounds isolated from the essential oil ofLedum palustre L. have been established on the basis of their spectral characteristics as p-mentha-1,8(10)-diene 3,9-epoxide (lepaloks) and 3,10-epoxygermacr-4(14)-en-8-one (lepakson). The chemical structure of ledene as a sesquiterpene hydrocarbon has been determined by chemical correlation.Tomsk State Medical Institute. Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, Novosibirsk. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 24–29, January–February, 1991.     

Preliminary investigation of water-soluble polysaccharides from Georgian plants

Water-soluble polysaccharides have been isolated from nine representatives of the Georgian flora belonging to seven families. According to preliminary results two of them contained glucomannans and the others contained acid arabinogalactans. A more detailed study of a polysaccharide from the fruit of the mistletoeViscum album has permitted it to be assigned to the class of pectin substances.Tbilisi State University. N. D. Zelinskii Institute of Organic Chemistry, Academy of Sciences of the USSR, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 330–335, May–June, 1989.     

Berberis alkaloids. XXI. Intebrine — A new N-benzylisoquinoline alkaloid from Berberis integerrima

A new N-benzylisoquinoline alkaloid — intebrine, with the composition C₂₀H₁₉NO₇ — has been isolated fromBerberis integerrima Bunge. The spatial structure of intebrine has been reliably determined by the x-ray structural method (diffractometer, CuK radiation, 972 reflections, direct method, R=0.048). Its chemical behavior, spectral characteristics, and mass-spectrometric fragmentation under electrom impact have been studied.Andizhan State Medical Institute. Institute of the Chemistry of Plant Substances, Uzbekistan Republic Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedeninii, No. 1, pp. 65–70, January–February, 1993.     

Alkaloids ofColchicum luteum

The paper gives a review of the alkaloids ofColchium luteum Baker from various growth sites. The structure of luteidine — one of the main alkaloids of the plant — has been established. In addition, two new alkaloids have been isolated from the plant and the structure of one of them has been established as collutine N-oxide.M. I Kalinin Turkmen Agricultural Institute, Ashkhabad, and V. I. Lenin Tashkent State University. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 810–815, November–December, 1985.     

Polysaccharides of the protein-lipoid-polysaccharide complex of the mycelium ofVerticillium dahliae. I. Isolation and fractionation

A phytotoxic PLPC has been isolated from the mycelium of the fungusVerticillium dahliae Kleb., strain 614. The polysaccharide component has been split out from the PLPC by mild acid hydrolysis. The polysaccharide has been fractionated and the monosaccharide compositions of the fractions have been determined. A phytotoxic polysaccharide homogeneous according to gel chromatography and chromatography on DEAE-cellulose has been isolated which consists of an -glucan containing a minor amount of D-glucosamine.Tashkent State University. All-Union Scientific-Research Institute of Agricultural Microbiology, Leningrad. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 774–777, November–December, 1979.