Medical Toxicology of Natural Substances.Foods,Fungi, Medicinal Herbs,Plants, and Venomous Animals. By Donald G. Barceloux.

John Wiley & Sons, Hoboken 2008. 1158 pp., hardcover € 162.50.—ISBN 978‐0471727613

     

无机物的ADME/Tox研究

无机物的吸收、分配、代谢和排除以及毒性（ADME/Tox)研究在药物和毒物研究中非常重要,近年来发展在细胞层次上应用高通量和计算机等技术系统探索药物先导化合物的ADME/Tox发展迅速。金属和其它无机化合物的ADME/Tox研究在国内外都还是一个新兴的、具有广阔发展前途的跨学科研究领域。本文综述了国内外对于铁和铜以及稀土等金属的化合物的ADME/Tox研究结果,提出了一些应该开展的工作和有待解决的问题。     

A Novel Sample Introduction Technique for the Simultaneous Determination of As, Se, Ge and Hg in Chinese Medicinal Material

A novel technique of Moveable Reduction Bed Hydride Generator（MRBHG）was applied tohe hydride generation or cold vapor generation of As,Se,Ge,and Hg existing In TraditionalChinese Medicinal Material（TCM）．The simultaneous determination of the multi－elements wasperformed with ICP－MS．A solid reduction system involving the use of potassiumtetraborohydride and tartaric acid was applied to generating metal hydride or cold vaporefficiently．The factors affecting the metal cold vapor generation were studied．The mainadvantage of the technique is that only a 4μL volume of sample was required for the cold vapor     

Practical Microwave Synthesis for Organic Chemists.Strategies,Instruments, and Protocols. Edited by C. Oliver Kappe,Doris Dallinger and Shaun Murphree.

Wiley‐VCH, Weinheim 2008. 300 pp., hardcover € 59.00.—ISBN 978‐3527320974