共查询到20条相似文献,搜索用时 31 毫秒
1.
Barbara R. Hillery James E. Girard Michele M. Schantz Stephen A. Wise 《Journal of separation science》1995,18(2):89-96
A novel p,p-cyanobiphenyl stationary phase (p-cyanobiphenyl, p-allyloxy methylpolysiloxane) has been evaluated for the GC investigation of polychlorinated biphenyls (PCBs). Several PCB congeners which coelute on the phases typically used for PCB analysis (e.g. 5% phenyl methylpolysiloxane) are separated on the p,p-cyanobiphenyl phase, including the hexachlorobiphenyl congeners PCB 163, PCB 164, and PCB 138. In this work, a p,p-cyanobiphenyl stationary phase was used to measure selected PCB congeners in two Standard Reference Materials (SRMs) available from the National Institute of Standards and Technology (NIST), and two Certified Reference Materials (CRMs) available from the Community Bureau of Reference (BCR). The materials analyzed were SRM 1588, Organics in Cod Liver Oil; SRM 1945, Organics in Whale Blubber; CRM 349, Chlorobiphenyls in Cod Liver Oil; and CRM 350, Chlorobiphenyls in Mackerel Oil. Concentrations are reported for several PCB congeners which coelute on the 5% phenyl methylpolysiloxane, including PCB 163 and PCB 164. 相似文献
2.
Two new marine sediment standard reference materials (SRMs) for the determination of organic contaminants 总被引:3,自引:0,他引:3
Wise SA Poster DL Schantz MM Kucklick JR Sander LC Lopez de Alda M Schubert P Parris RM Porter BJ 《Analytical and bioanalytical chemistry》2004,378(5):1251-1264
Two new marine sediment standard reference materials (SRMs), SRM 1941b Organics in Marine Sediment and SRM 1944 New York/New Jersey Waterway Sediment, have been recently issued by the National Institute of Standards and Technology (NIST) for the determination of organic contaminants including polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyl (PCB) congeners, and chlorinated pesticides. Both sediment SRMs were analyzed using multiple analytical methods including gas chromatography/mass spectrometry (GC/MS) on columns with different selectivity, reversed-phase liquid chromatography with fluorescence detection (for PAHs only), and GC with electron capture detection (for PCBs and pesticides only). SRM 1941b has certified concentrations for 24 PAHs, 29 PCB congeners, and 7 pesticides, and SRM 1944 has certified concentrations for 24 PAHs, 29 PCB congeners, and 4 pesticides. Reference concentrations are also provided for an additional 58 (SRM 1941b) and 39 (SRM 1944) PAHs, PCB congeners, and pesticides. SRM 1944, which was collected from multiple sites within New York/New Jersey coastal waterways, has contaminant concentrations that are generally a factor of 10–20 greater than SRM 1941b, which was collected in the Baltimore (Maryland) harbor. These two SRMs represent the most extensively characterized marine sediment certified reference materials available for the determination of organic contaminants.Electronic Supplementary Material Supplementary material is available in the online version of this article at . A link in the frame on the left on that page takes you directly to the supplementary material. 相似文献
3.
The concentrations of three non-ortho ("coplanar") polychlorinated biphenyls, 3,3',4,4'-tetrachlorobiphenyl (IUPAC PCB 77), 3,3',4,4',5-pentachlorobiphenyl (IUPAC PCB 126), and 3,3',4,4',5,5'-hexachlorobiphenyl (IUPAC PCB 169), were determined in five NIST Standard Reference Materials (SRMs) of environmental and biological interest. The measured levels were approximately between (0.2 to 1.3) ng/g in SRM 1588a (Organics in Cod Liver Oil), (0.3 to 9) ng/g in SRM 1944 (New York/New Jersey Waterway Sediment), (0.2 to 0.4) ng/g in SRM 1945 (Organics in Whale Blubber), (1 to 18) ng/g in SRM 2974 (Organics in Freeze-dried Mussel Tissue [Mytilus edulis]), and (0.1 to 0.4) ng/g in candidate SRM 1946 (Lake Superior Fish Tissue). PCB 169 was present at < 0.1 ng/g in SRMs 1944 and 2974. 相似文献
4.
W. W. Brubaker Jr. M. M. Schantz S. A. Wise 《Analytical and bioanalytical chemistry》2000,367(5):401-406
The concentrations of three non-ortho (“coplanar”) polychlorinated biphenyls, 3,3′,4,4′-tetrachlorobiphenyl (IUPAC PCB 77), 3,3′,4,4′,5-pentachlorobiphenyl (IUPAC PCB 126), and 3,3′,4,4′,5,5′-hexachlorobiphenyl (IUPAC PCB 169), were determined in five NIST Standard Reference Materials (SRMs) of environmental and biological interest. The measured levels were approximately between (0.2 to 1.3) ng/g in SRM 1588?a (Organics in Cod Liver Oil), (0.3 to 9) ng/g in SRM 1944 (New York/New Jersey Waterway Sediment), (0.2 to 0.4) ng/g in SRM 1945 (Organics in Whale Blubber), ¶(1 to 18) ng/g in SRM 2974 (Organics in Freeze-dried Mussel Tissue [Mytilus edulis]), and (0.1 to 0.4) ng/g ¶in candidate SRM 1946 (Lake Superior Fish Tissue). PCB 169 was present at < 0.1 ng/g in SRMs 1944 and 2974. 相似文献
5.
Poster DL Kucklick JR Schantz MM Porter BJ Leigh SD Wise SA 《Analytical and bioanalytical chemistry》2003,375(2):223-241
The concentrations of a wide range of polychlorinated biphenyl congeners (PCBs) and chlorinated pesticides in a fish tissue Standard Reference Material (SRM) have been determined using multiple methods of analysis. This material, SRM 1946, Lake Superior Fish Tissue, was recently issued by the National Institute of Standards and Technology (NIST) and complements a suite of marine environmental natural-matrix SRMs that are currently available from NIST for the determination of organic contaminants such as aliphatic hydrocarbons, polycyclic aromatic hydrocarbons (PAHs), PCBs, and chlorinated pesticides. SRM 1946 is a fresh tissue homogenate (frozen) prepared from filleted adult lake trout (Salvelinus namaycush namaycush) collected from the Apostle Islands region of Lake Superior. SRM 1946 has certified and reference concentrations for PCB congeners, including the three non- ortho PCB congeners, and chlorinated pesticides. Certified concentrations are available for 30 PCB congeners and 15 chlorinated pesticides. Reference concentrations are available for 12 PCB congeners and 2 chlorinated pesticides. In addition, SRM 1946 is characterized for additional chemical constituents and properties: fatty acids, extractable fat, methylmercury, total mercury, selected trace elements, proximates, and caloric content. The characterization of chlorinated compounds is described in this paper with an emphasis on the approach used for the certification of the concentrations of PCB congeners and chlorinated pesticides. The PCB congener and chlorinated pesticide data are also compared to concentrations in other marine natural-matrix reference materials available from NIST (fish oil, mussel tissue, whale blubber, and a second fresh frozen fish tissue homogenate prepared from filleted adult lake trout collected from Lake Michigan) and from other organizations such as the National Research Council Canada (ground whole carp), the International Atomic Energy Agency (fish homogenate), and the European Commission Joint Research Centre [fish oils (cod and mackerel) and mussel tissue]. 相似文献
6.
D. L. Poster Michele M. Schantz Stephen A. Wise Mark G. Vangel 《Fresenius' Journal of Analytical Chemistry》1999,363(4):380-390
A previously issued National Institute of Standards and Technology (NIST) Standard Reference Material (SRM), SRM 1649, Urban
Dust/Organics has been analyzed for chlorinated organic contaminants (polychlorinated biphenyls and chlorinated pesticides)
to provide certified values for a new class of compounds relative to the former certification. The material will be reissued
as SRM 1649a. Four different analytical techniques were used. Specifically, two different methods of extraction (Soxhlet and
pressurized fluid extraction) were used in conjunction with sample analysis by gas chromatography with two different columns
(5% phenyl-methyl polysiloxane and 50% methyl C-18 dimethyl polysiloxane) that exhibit distinct selectivity, and with two
different modes of detection (electron capture detection and mass spectrometry). The results from these techniques were combined
to generate certified concentrations for 35 PCB congeners (some in combination) and 8 chlorinated pesticides. Ancillary assessments
of additional chemical and physical properties of SRM 1649a include homogeneity, moisture, total organic carbon, extractable
mass, and the particle-size distribution. The approach and the results for the certification of the PCB congeners and chlorinated
pesticides in SRM 1649a, and the determination of the additional chemical and physical properties are described. In addition,
the determination of PCBs and chlorinated pesticides in SRM 1648, Urban Particulate Matter (a particulate material certified
for inorganic constituents), is also discussed although certified values are not presented.
Received: 8 June 1998 / Revised: 4 September 1998 / Accepted: 26 September 1998 相似文献
7.
D. L. Poster Michele M. Schantz Stephen A. Wise Mark G. Vangel 《Analytical and bioanalytical chemistry》1999,363(4):380-390
A previously issued National Institute of Standards and Technology (NIST) Standard Reference Material (SRM), SRM 1649, Urban
Dust/Organics has been analyzed for chlorinated organic contaminants (polychlorinated biphenyls and chlorinated pesticides)
to provide certified values for a new class of compounds relative to the former certification. The material will be reissued
as SRM 1649a. Four different analytical techniques were used. Specifically, two different methods of extraction (Soxhlet and
pressurized fluid extraction) were used in conjunction with sample analysis by gas chromatography with two different columns
(5% phenyl-methyl polysiloxane and 50% methyl C-18 dimethyl polysiloxane) that exhibit distinct selectivity, and with two
different modes of detection (electron capture detection and mass spectrometry). The results from these techniques were combined
to generate certified concentrations for 35 PCB congeners (some in combination) and 8 chlorinated pesticides. Ancillary assessments
of additional chemical and physical properties of SRM 1649a include homogeneity, moisture, total organic carbon, extractable
mass, and the particle-size distribution. The approach and the results for the certification of the PCB congeners and chlorinated
pesticides in SRM 1649a, and the determination of the additional chemical and physical properties are described. In addition,
the determination of PCBs and chlorinated pesticides in SRM 1648, Urban Particulate Matter (a particulate material certified
for inorganic constituents), is also discussed although certified values are not presented.
Received: 8 June 1998 / Revised: 4 September 1998 / Accepted: 26 September 1998 相似文献
8.
Preparation and analysis of a marine sediment reference material for the determination of trace organic constituents 总被引:1,自引:0,他引:1
Michele M. Schantz Bruce A. Benner Stephen N. Chesler Barbara J. Koster Karen E. Hehn Susan F. Stone W. Robert Kelly Rolf Zeisler Stephen A. Wise 《Fresenius' Journal of Analytical Chemistry》1990,338(4):501-514
Summary A new marine sediment Standard Reference Material (SRM) has been prepared and analyzed for the determination of trace organic constituents. SRM 1941, Organics in Marine Sediment, has been certified for concentrations of 11 PAHs using results obtained from gas chromatography (GC) with flame ionization detection, gas chromatography-mass spectrometry, and liquid chromatography with fluorescence detection. Non-certified values for 24 additional PAHs are also reported. GC with electron capture detection was used to provide non-certified concentrations for 15 PCB congeners and 7 chlorinated pesticides. In addition to the organic contaminants, concentrations of 32 major and trace elements were determined using neutron activation analysis, and the sulfur content was also determined using isotope dilution thermal ionization mass spectrometry. 相似文献
9.
Kucklick JR Tuerk KJ Vander Pol SS Schantz MM Wise SA 《Analytical and bioanalytical chemistry》2004,378(5):1147-1151
Polybrominated diphenyl ether (PBDE) congeners and components of the complex mixture toxaphene are stable in the environment and readily bioaccumulated into wildlife and human tissues. PBDEs are presently used in large quantities worldwide as flame retardants in textiles, furniture, computer equipment, and cables. Toxaphene is a complex mixture of chlorinated bornanes and bornenes that was the most heavily used pesticide in the United States until it was banned in 1982; however, some countries continue to use toxaphene. The National Institute of Standards and Technology has quantified PBDE congeners and toxaphene in several available Standard Reference Materials (SRMs) using methods of gas chromatography with electron impact mass spectrometry (GC-EI-MS) and GC negative chemical ionization (NCI) MS, respectively. SRM 1588a Organics in Cod Liver Oil and SRM 1945 Organics in Whale Blubber were examined for PBDE congeners 47, 99, 100, 153, and 154, total toxaphene, and toxaphene congeners 26, 50, and 62. SRM 1946 Lake Superior Fish Tissue was also examined for total toxaphene and toxaphene congeners. The sum of the PBDE congeners (mean, (1 SD) wet basis) for SRM 1945 was 150 ng g–1 (7 ng g–1). The concentration of PBDE 47 in SRM 1588a was 82.7 ng g–1 (2.8 ng g–1). Other PBDEs were detected in SRM 1588a but were not quantified due their low levels. The total toxaphene (wet mass basis) was 1,210 ng g–1 (127 ng g–1), 1,960 ng g–1 (133 ng g–1), and 3,980 ng g–1 (248 ng g–1) in SRMs 1945, 1946, and 1588a, respectively. The values for PBDEs and toxaphene determined in the SRMs, while not certified, indicate that the SRMs will be suitable control materials for PBDE and toxaphene analyses. 相似文献
10.
Certification of standard reference material (SRM) 1941a, organics in marine sediment 总被引:2,自引:0,他引:2
Michele M. Schantz Bruce A. Benner Jr. Melinda J. Hays W. Robert Kelly Robert D. Vocke Jr. Rabia Demiralp Robert R. Greenberg Susannah B. Schiller Gunnar G. Lauenstein Stephen A. Wise 《Fresenius' Journal of Analytical Chemistry》1995,352(1-2):166-173
SRM 1941a, Organics in Marine Sediment, has been recently issued with certified concentrations for 23 polycyclic aromatic hydrocarbons, 21 polychlorinated biphenyl congeners, 6 chlorinated pesticides, and sulfur. Noncertified concentrations have been also reported for additional PAHs, PCB congeners, and chlorinated pesticides and for percent total organic carbon (TOC), aliphatic hydrocarbons, and trace elements. SRM 1941a is the most extensively characterized natural matrix SRM issued by the National Institute of Standards and Technology (NIST). 相似文献
11.
John R. Kucklick Michele M. Schantz Rebecca S. Pugh Barbara J. Porter Dianne L. Poster Paul R. Becker Teri K. Rowles Stefan Leigh Stephen A. Wise 《Analytical and bioanalytical chemistry》2010,397(2):423-432
The National Institute of Standards and Technology (NIST) has a diverse collection of control materials derived from marine
mammal blubber, fat, and serum. Standard Reference Material (SRM) 1945 Organics in Whale Blubber was recertified for polychlorinated
biphenyl (PCB) congeners, organochlorine pesticides, and polybrominated diphenyl ether (PBDE) congeners. SRM 1945 has also
been assigned mass fraction values for compounds not frequently determined in marine samples including toxaphene congeners,
coplanar PCBs, and methoxylated PBDE congeners which are natural products. NIST also has assigned mass fraction values, as
a result of interlaboratory comparison exercises, for PCB congeners, organochlorine pesticides, PBDE congeners, and fatty
acids in six homogenate materials produced from marine mammal blubber or serum. The materials are available from NIST upon
request; however, the supply is very limited for some of the materials. The materials include those obtained from pilot whale
blubber (Homogenates III and IV), Blainville’s beaked whale blubber (Homogenate VII), polar bear fat (Homogenate VI), and
California sea lion serum (Marine Mammal Control Material-1 Serum) and blubber (Homogenate V). 相似文献
12.
Richard E. Rebbert Stenhen N. Chesler Franklin R. Guenther Barbara J. Koster Reenie M. Parris Michele M. Schantz Stephen A. Wise 《Fresenius' Journal of Analytical Chemistry》1992,342(1-2):30-38
Summary A river sediment Standard Reference Material (SRM) has been prepared and analyzed for determination of the concentrations of trace organic constituents. SRM 1939, Polychlorinated Biphenyls (PCBs) in River Sediment A, has been certified for the concentrations of three PCB congeners using the results obtained from capillary column gas chromatography with electron capture detection (GC-ECD) and from multidimensional (dual column) capillary gas chromatography with mass spectrometric detection (MCGC-MSD). For SRM certification, two independent analytical procedures are usually required. If only one analytical technique is used or if the procedures are not independent, then the concentrations are reported as noncertified or informational values rather than certified values. Noncertified values for 14 additional PCB congeners and five chlorinated pesticides, determined by GC-ECD, are also reported as well as noncertified concentrations for five polycyclic aromatic hydrocarbons (PAHs), determined using gas chromatography with mass spectrometric detection (GC-MSD). SRM 1939 complements SRM 1941, Organics in Marine Sediment, since both materials have 12 PCB congeners, five PAHs and five chlorinated pesticides in common. However, the concentrations differ by an order of magnitude for PAHs, and from one to over two orders of magnitude for the PCB congeners and chlorinated pesticides. 相似文献
13.
Stapleton HM Harner T Shoeib M Keller JM Schantz MM Leigh SD Wise SA 《Analytical and bioanalytical chemistry》2006,384(3):791-800
Polybrominated diphenyl ethers (PBDEs) have been measured for the first time in three different indoor dust Standard Reference
Materials (SRMs) prepared by the National Institute of Standards and Technology (NIST). Two of these, SRM 2583 (Trace Elements
in Indoor Dust) and SRM 2584 (Trace Elements in Indoor Dust), have been certified previously for lead and other inorganic
constituents. A third, SRM 2585 (Organics in Indoor Dust), is a new indoor dust reference material prepared by NIST which
will be certified for various organic compounds (polycyclic aromatic hydrocarbons, pesticides and polychlorinated biphenyls)
in 2005 including certified concentrations for 16 individual PBDE congeners and reference values for an additional three PBDE
congeners. Dust SRMs were analyzed for 30 PBDE congeners using high-resolution gas chromatography combined with low-resolution
mass spectrometry operated in both negative chemical ionization (GC/ECNI–MS) and electron impact ionization (GC/EI–MS) modes.
Sensitivity was an order of magnitude higher using GC/ECNI–MS relative to GC/EI–MS. These SRMs have been characterized and
compared to the three PBDE commercial products (pentaBDE, octaBDE and decaBDE). PentaBDE and DecaBDE were present in all three
SRMs and were the dominant commercial products, making up approximately 33% and 58%, respectively. Recent studies suggest
that house dust may be a leading source of human exposure to PBDEs. These SRMs are the first reference materials with certified
concentrations for PBDEs, which will aid in validating future measurements of PBDEs in house dust and other similar matrices.
Electronic Supplementary Material Supplementary material is available for this article at http://dx.doi.org/ 10.1007/s00216-005-0227-y 相似文献
14.
Robert Alvarez 《Fresenius' Journal of Analytical Chemistry》1990,338(4):466-468
Summary NIST issues food related, chemical composition standard reference materials for validating food analyses. SRMs certified for inorganic constituents are: Non-Fat Milk Powder (SRM 1549), Oyster Tissue (SRM 1566a), Bovine Liver (SRM 1577a), Wheat Flour (SRM 1567a), Rice Flour (SRM 1568a), and Total Diet (SRM 1548). The certificate of analysis for the total diet SRM also provides a certified concentration for cholesterol. Oyster tissue, a renewal SRM, is certified for 25 elements including 6 (Al, Cl, I, P, S, and V), that had not been certified in the previously issued SRM 1566. The elemental certified concentrations are based on concordant results of two or more independent analytical methods. The chemical compositions of the six food matrix SRMs are tabulated. Three food matrix SRMs certified for organic constituents are: Cholesterol and Fat-Soluble Vitamins in Coconut Oil (SRM 1563), Cholesterol in Whole Egg Powder (SRM 1845) and Organics in Cod Liver Oil (SRM 1588). Serum and urine matrix SRMs are also available that may be useful for metabolic and bioavailability studies. 相似文献
15.
Schantz MM Keller JM Leigh S Patterson DG Sharpless KE Sjödin A Stapleton HM Swarthout R Turner WE Wise SA 《Analytical and bioanalytical chemistry》2007,389(4):1201-1208
The Certificate of Analysis for SRM 1589a PCBs, Pesticides, PBDEs, and Dioxins/Furans in Human Serum has been updated to include
certified concentration values for 27 polychlorinated biphenyl (PCB) congeners, three chlorinated pesticides, and four polybrominated
diphenyl ether (PBDE) congeners as well as reference concentration values for 27 additional PCB congeners, six additional
chlorinated pesticides, three additional PBDE congeners, and selected polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). This represents an addition of concentration values for 29 PCB
congeners and for PBDE congeners that were not quantified in the previous issue of SRM 1589a. With the increased number of
certified and reference concentration values for PCBs and the inclusion of certified and reference concentration values for
PBDEs, this serum material will be more useful as a reference material for contaminant monitoring in human tissues and fluids.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献
16.
Synthetic musk fragrances have been measured in water, air, sediments, sewage sludge, and biota worldwide. As the study of
the environmental fate and impacts of these compounds progresses, the need for Standard Reference Materials (SRMs) for these
compounds to facilitate analytical method improvement and interlaboratory comparisons becomes increasingly important. The
National Institute of Standards and Technology (NIST) issues environmental matrix SRMs with certified concentrations for a
variety of persistent organic pollutants including polycyclic aromatic hydrocarbons (PAHs), chlorinated pesticides, and polychlorinated
biphenyl congeners (PCBs). Until now synthetic musk fragrance concentrations have not been reported in NIST SRMs. The objective
of this study was to provide reference values for several commonly detected synthetic musk fragrances in several NIST natural
matrix SRMs. In this study five polycyclic musk fragrances [HHCB (1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-γ-2-benzopyran), AHTN (7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene), ADBI (4-acetyl-1,1-dimethyl-6-tert-butylindane), AHMI (6-acetyl-1,1,2,3,3,5-hexamethylindane), and ATII (5-acetyl-1,1,2,6-tetramethyl-3-isopropylindane] and
two nitro musk fragrances [musk xylene (1-tert-butyl-3,5-dimethyl-2,4,6-trinitrobenzene) and musk ketone (4-tert-butyl-3,5-dinitro-2,6-dimethylacetophenone)] were measured in selected environmental SRMs. Gas chromatography–electron impact
mass spectrometry (GC/EI-MS) was used for all analyses. HHCB was the most frequently detected synthetic musk fragrance and
was detected in SRM 2585 Organic Contaminants in House Dust, SRM 2781 Domestic Sludge, SRM 1974b Organics in Mussel Tissue
(Mytilus edulis), and SRM 1947 Lake Michigan Fish Tissue. It was not detected in SRM 1946 Lake Superior Fish Tissue or SRM 1945 Organics
in Whale Blubber. Concentrations of HHCB in these SRMs ranged from 1.12 ng/g in SRM 1947 to 92,901 ng/g in SRM 2781. All of
the polycyclic musk fragrances were detected in SRM 2781 and all of the target compounds were detected in SRM 2585.
Electronic supplementary material Supplementary material is available for this article at and is accessible to authorized users. 相似文献
17.
Michele M. Schantz Gauthier Eppe Jean-François Focant Coreen Hamilton N. Alan Heckert Rebecca M. Heltsley Dale Hoover Jennifer M. Keller Stefan D. Leigh Donald G. Patterson Jr Adam L. Pintar Katherine E. Sharpless Andreas Sjödin Wayman E. Turner Stacy S. Vander Pol Stephen A. Wise 《Analytical and bioanalytical chemistry》2013,405(4):1203-1211
Four new Standard Reference Materials (SRMs) have been developed to assist in the quality assurance of chemical contaminant measurements required for human biomonitoring studies, SRM 1953 Organic Contaminants in Non-Fortified Human Milk, SRM 1954 Organic Contaminants in Fortified Human Milk, SRM 1957 Organic Contaminants in Non-Fortified Human Serum, and SRM 1958 Organic Contaminants in Fortified Human Serum. These materials were developed as part of a collaboration between the National Institute of Standards and Technology (NIST) and the Centers for Disease Control and Prevention (CDC) with both agencies contributing data used in the certification of mass fraction values for a wide range of organic contaminants including polychlorinated biphenyl (PCB) congeners, chlorinated pesticides, polybrominated diphenyl ether (PBDE) congeners, and polychlorinated dibenzo-p-dioxin (PCDD) and dibenzofuran (PCDF) congeners. The certified mass fractions of the organic contaminants in unfortified samples, SRM 1953 and SRM 1957, ranged from 12 ng/kg to 2200 ng/kg with the exception of 4,4′-DDE in SRM 1953 at 7400 ng/kg with expanded uncertainties generally <14 %. This agreement suggests that there were no significant biases existing among the multiple methods used for analysis. Figure
Comparison of Concentrations of Selected Compounds in Human Serum and Human Milk Standard Reference Materials (SRMs) 相似文献
18.
Poster DL Schantz MM Kucklick JR Lopez de Alda MJ Porter BJ Pugh R Wise SA 《Analytical and bioanalytical chemistry》2004,378(5):1213-1231
Three new mussel tissue standard reference materials (SRMs) have been developed by the National Institute of Standards and Technology (NIST) for the determination of the concentrations of organic contaminants. The most recently prepared material, SRM 1974b, is a fresh frozen tissue homogenate prepared from mussels (Mytilus edulis) collected in Boston Harbor, Massachusetts. The other two materials, SRMs 2977 and 2978, are freeze-dried tissue homogenates prepared from mussels collected in Guanabara Bay, Brazil and Raritan Bay, New Jersey, respectively. All three new mussel tissue SRMs complement the current suite of marine natural-matrix SRMs available from NIST that are characterized for a wide range of contaminants (organic and inorganic). SRM 1974b has been developed to replace its predecessor SRM 1974a, Organics in Mussel Tissue, for which the supply is depleted. Similarly, SRMs 2977 and 2978 were developed to replace a previously available (supply depleted) freeze-dried version of SRM 1974a, SRM 2974, Organics in Freeze-Dried Mussel Tissue. SRM 1974b is the third in a series of fresh frozen mussel tissue homogenate SRMs prepared from mussels collected in Boston Harbor starting in 1988. SRM 1974b has certified concentration values for 22 polycyclic aromatic hydrocarbons (PAHs), 31 polychlorinated biphenyl congeners (PCBs), and 7 chlorinated pesticides. Reference values are provided for additional constituents: 16 PAHs, 8 PCBs plus total PCBs, 6 pesticides, total extractable organics, methylmercury, and 11 trace elements. PAH concentrations range from about 2 ng g–1 dry mass (cyclopenta[cd]pyrene) to 180 ng g–1 dry mass (pyrene). PCB concentrations range from about 2 ng g–1 dry mass (PCB 157) to 120 ng g–1 dry mass (PCB 153). The reference value for total PCBs in SRM 1974b is (2020 ± 420) ng g–1 dry mass. Pesticide concentrations range from about 4 ng g–1 dry mass (4,4-DDT) to 40 ng g–1 dry mass (4,4-DDE). SRM 2977 has certified values for 14 PAHs, 25 PCB congeners, 7 pesticides, 6 trace elements, and methylmercury. Reference values for 16 additional PAHs and 9 inorganic constituents are provided, and information values are given for 23 additional trace elements. SRM 2978 has certified and reference concentrations for 41 and 22 organic compounds, respectively, and contains contaminant levels similar to those of SRM 1974b. Organic contaminant levels in SRM 2977 (mussels from Guanabara Bay, Brazil) are typically a factor of 2 to 4 lower than those in SRM 1974b and SRM 2978. The organic contaminant concentrations in each new mussel tissue SRM are presented and compared in this paper. In addition, a chronological review of contaminant concentrations associated with mussels collected in Boston Harbor is discussed as well as a stability assessment of SRM 1974a.Electronic Supplementary Material Supplementary material is available in the online version of this article at . A link in the frame on the left on that page takes you directly to the supplementary material. 相似文献
19.
Standard reference materials for foods and dietary supplements 总被引:1,自引:0,他引:1
Sharpless KE Thomas JB Christopher SJ Greenberg RR Sander LC Schantz MM Welch MJ Wise SA 《Analytical and bioanalytical chemistry》2007,389(1):171-178
Well-characterized certified reference materials are needed by laboratories in the food testing, dietary supplement, and nutrition
communities to facilitate compliance with labeling laws and improve the accuracy of information provided on product labels,
so that consumers can make good choices. As a result of the enactment of the Nutrition Labeling and Education Act of 1990
and the Infant Formula Act of 1980, the National Institute of Standards and Technology (NIST) worked to develop a series of
food-matrix standard reference materials (SRMs) characterized for nutrient concentrations. These include SRM 1544 Fatty Acids
and Cholesterol in a Frozen Diet Composite, SRM 1546 Meat Homogenate, SRM 1548a Typical Diet, SRM 1566b Oyster Tissue, SRM
1846 Infant Formula, SRM 1946 Lake Superior Fish Tissue, SRM 1947 Lake Michigan Fish Tissue, SRM 2383 Baby Food Composite,
SRM 2384 Baking Chocolate, SRM 2385 Slurried Spinach, and SRM 2387 Peanut Butter. With the enactment of the Dietary Supplement
Health and Education Act of 1994, NIST has been working to develop suites of dietary supplement SRMs characterized for active
and marker compounds and for toxic elements and pesticides, where appropriate. An updated SRM 1588b Organics in Cod Liver
Oil, a suite of ephedra-containing materials (SRMs 3240–3245), a carrot extract in oil (SRM 3276), and a suite of ginkgo-containing
materials (SRMs 3246–3248) are available. Several other materials are currently in preparation. Dietary supplements are sometimes
provided in forms that are food-like; for these, values may also be assigned for nutrients, for example SRM 3244 Ephedra-Containing
Protein Powder. Both the food-matrix and dietary supplement reference materials are intended primarily for validation of analytical
methods. They may also be used as “primary control materials” in assignment of values to in-house (secondary) control materials
to confirm accuracy and to establish measurement traceability to NIST. 相似文献
20.
Najam AR Korver MP Williams CC Burse VW Needham LL 《Journal of AOAC International》1999,82(1):177-185
An analytical method is presented for precise identification and quantitation of 29 specific polychlorinated biphenyl (PCB) congeners and 15 chlorinated pesticides in human serum. Analyte surrogates PCB 30, PCB 204, 2,2',4,4',5,5'-hexabromo-biphenyl, perthane, alpha-hexachlorocyclohexane, and dichlorobenzophenone were added to each sample. The serum was extracted with an organic solvent and separated by adsorption chromatography into 3 elution fractions for high-resolution gas chromatographic analysis. Each fraction was analyzed by dual-column capillary chromatography followed by electron capture detection. Two capillary columns, DB-5 and DB-1701, with different polarities were used to increase selectivity for each analyte. Quantitation was performed by selecting 2 sets of calibration standard mixtures and 1,2-dichloronaphthalene as an internal standard. Mean recoveries ranged from 39 to 126% for selected analytes and from 31 to 88% for surrogates. Detection limits for specific congeners and pesticides are reported. Typical chromatographic profiles of calibration standard mixtures, as well as a human sample, are illustrated. Verification of each analyte is assessed, and results of analyses of selected human samples and quality control criteria used to ensure data validity also are presented. 相似文献