共查询到20条相似文献,搜索用时 62 毫秒
1.
S?ren Krach Isabelle Blümel Dominic Marjoram Tineke Lataster Lydia Krabbendam Jochen Weber Jim van Os Tilo Kircher 《BMC neuroscience》2009,10(1):9
Background
The ability to mentalize, i.e. develop a Theory of Mind (ToM), enables us to anticipate and build a model of the thoughts, emotions and intentions of others. It has long been hypothesised that women differ from men in their mentalizing abilities. In the present fMRI study we examined the impact of (1) gender (women vs. men) and (2) game partner (human vs. computer) on ToM associated neural activity in the medial prefrontal cortex. Groups of men (n = 12) and women (n = 12) interacted in an iterated classical prisoner's dilemma forced choice situation with alleged human and computer partners who were outside the scanner. 相似文献2.
Background
The capsaicin (vanilloid) receptor, VR1, is an agonist-activated ion channel expressed by sensory neurons that serves as a detector of chemical and thermal noxious stimuli. 相似文献3.
Nelson F Eng Srinivas Garlapati Volker Gerdts Lorne A Babiuk George K Mutwiri 《Journal of immune based therapies and vaccines》2010,8(1):4
Background
We previously demonstrated that polyphosphazenes, particularly PCEP, enhance immune responses in mice immunized subcutaneously and intranasally. The objective of the present study was to investigate the efficacy of polyphosphazenes as adjuvants when delivered through different routes of vaccine administration. 相似文献4.
Background
Neurological diseases and neuropsychiatric disorders that vary depending on female life stages suggest that sex hormones may influence the function of neurotransmitter regulatory machinery such as the dopamine transporter (DAT). 相似文献5.
Lindsay J Hall Simon Clare Gordon Dougan 《Journal of immune based therapies and vaccines》2010,8(1):5
Background
Intranasal immunisation is potentially a very effective route for inducing both mucosal and systemic immunity to an infectious agent. 相似文献6.
Background
Growth cone migratory patterns show evidence of both deterministic and stochastic search modes. 相似文献7.
Background
Results of the Women's Health Initiative Memory Study (WHIMS) raised concerns regarding the timing and formulation of hormone interventions. Conjugated equine estrogens (CEE), used as the estrogen therapy in the WHIMS trial, is a complex formulation containing multiple estrogens, including several not secreted by human ovaries, as well as other biologically active steroids. Although the full spectrum of estrogenic components present in CEE has not yet been resolved, 10 estrogens have been identified. In the present study, we sought to determine which estrogenic components, at concentrations commensurate with their plasma levels achieved following a single oral dose of 0.625 mg CEE (the dose used in the WHIMS trial) in women, are neuroprotective and whether combinations of those neuroprotective estrogens provide added benefit. Further, we sought, through computer-aided modeling analyses, to investigate the potential correlation of the molecular mechanisms that conferred estrogen neuroprotection with estrogen interactions with the estrogen receptor (ER). 相似文献8.
Shoji Tanaka 《BMC neuroscience》2008,9(1):41
Background
The GABAergic system in the brain seems to be dysfunctional in various psychiatric disorders. Many studies have suggested so far that, in schizophrenia patients, GABAergic inhibition is selectively but consistently reduced in the prefrontal cortex (PFC). 相似文献9.
Bita Baghernejad Majid M. Heravi Hossein A. Oskooie Nargess Poormohammad Maliheh Khorshidi Yahia Sh. Beheshtiha 《Molecular diversity》2011,15(1):245-248
Abstract
A simple and efficient synthesis of N-cyclohexyl-benzofuran derivatives was achieved via a one-pot three-component reaction of cyclohexylisocyanide, an aromatic aldehydes, and phenols in DMF for 10 h with good yields. 相似文献10.
Background
Hemodialysis patient are at high risk for hepatitis B virus (HBV) infection. 相似文献11.
Hana?Munakata Yukiko?Nakamura Kazumasa?Matsumoto-Miyai Kouichi?Itoh Hironobu?Yamasaki Sadao?Shiosaka
Background
The importance of L1 expression in the matured brain is suggested by physiological and behavioral studies showing that L1 is related to hippocampal plasticity and fear conditioning. The distribution of L1 in mouse brain might provide a basis for understanding its role in the brain. 相似文献12.
Background
CNS injury including stroke, infection, and tumor growth lead to astrogliosis, a process that involves upregulation of glial fibrillary acidic protein (GFAP) in astrocytes. However, the kinetics of astrogliosis that is related to these insults (i.e. tumor) is largely unknown. 相似文献13.
Franca Scintu Camilla Reali Rita Pillai Manuela Badiali Adele Maria Sanna Francesca Argiolu Maria Serafina Ristaldi Valeria Sogos 《BMC neuroscience》2006,7(1):14-12
Background
It has recently been demonstrated that the fate of adult cells is not restricted to their tissues of origin. In particular, it has been shown that bone marrow stem cells can give rise to cells of different tissues, including neural cells, hepatocytes and myocytes, expanding their differentiation potential. 相似文献14.
Perceiving pitch absolutely: Comparing absolute and relative pitch possessors in a pitch memory task
Background
The perceptual-cognitive mechanisms and neural correlates of Absolute Pitch (AP) are not fully understood. The aim of this fMRI study was to examine the neural network underlying AP using a pitch memory experiment and contrasting two groups of musicians with each other, those that have AP and those that do not. 相似文献15.
Graphical abstract
相似文献16.
Background
A distinctive property of SII is that it is the first cortical stage of the somatosensory projection pathway that integrates information arising from both sides of the body. However, there is very little known about how inputs across the body mid-line are processed within SII. 相似文献17.
Angela?M?Jaramillo Xiangzhong?Zheng Yi?Zhou Defne?A?Amado Amanda?Sheldon Amita?Sehgal Irwin?B?Levitan
Background
SLOB binds to and modulates the activity of the Drosophila Slowpoke (dSlo) calcium activated potassium channel. Recent microarray analyses demonstrated circadian cycling of slob mRNA. 相似文献18.
19.
Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation 总被引:1,自引:0,他引:1
Tim R Mercer Irfan A Qureshi Solen Gokhan Marcel E Dinger Guangyu Li John S Mattick Mark F Mehler 《BMC neuroscience》2010,11(1):14
Background
Long non-protein-coding RNAs (ncRNAs) are emerging as important regulators of cellular differentiation and are widely expressed in the brain. 相似文献20.