Berberis alkaloids 2’-N-methylberbamine fromBerberis oblonga

Summary A new alkaloid has been isolated from the roots ofBerberis oblonga. On the basis of spectral characteristics and chemical transformations, its structure has been determined as 2-N-methylberbamine.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. M. I. Kalinin Andizhan State Medical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 227–231, March–April, 1978.     

Alkaloids ofPapaver orientale

Summary From the combined alkaloids ofPapaver orientale we have isolated isothebaine, oripavine, thebaine, mecambridine, orientalidine, alpinigenine, protopine, bracteoline, oripavidine, and the new alkaloid isothebaidine, the structure of which has been established.Institute of the Chemistry of Plant Substances, Tashkent. Pyatigorsk Pharmaceutical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 474–475, July–August, 1978.     

Alkaloids of the epigeal part ofAconitum kirinense

Lepenine and the new alkaloid lepenine N-oxide have been isolated from the epigeal part ofAcontium kirinense.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 734–736, September–October, 1993.     

Berberis alkaloids. XVI. Structure of berpodine

The alkaloid composition of young shoots ofBerberis heteropoda has been studied. Together with known alkaloids, we have isolated the new dimeric base berpodine and have established its structure by a study of spectral characteristics and by chemical transformations. The known alkaloid isotetrandrine has also been isolated from this plant, for the first time.Institute of Chemistry of Plant Substances Uzbekistan Republic Academy of Sciences, Tashkent. Andizhan State Medical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 264–267, March–April, 1993.     

Structure of regecoline

A new alkaloid, regecoline, with mp 312–314°C, has been isolated from the fraction of phenolic-basic alkaloids ofColchicum kesselringii Rgl. growing in the Syrdar'-inskaya region. The structure of this alkaloid has been established on the basis of the results of a study of chemical transformations, spectral characteristics, and mutual transitions with kesselringine.V. I. Lenin Tashkent State University and M. I. Kalinin Turkmen Agricultural Institute, Ashkhabad. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 248–253, March–April, 1985.     

New C-nor,D-homosteroid alkaloid germinine fromVeratrum lobelianum

The results are given of an investigation of the alkaloid composition of the hypogeal part ofVeratrum lobelianum Bernh. The new alkaloid germinine has been isolated and its structure has been established on the basis of physicochemical properties and chemical transformations.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 40 64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 620–622, July–August, 1997.     

Alkaloids ofNitraria komarovii. X. Structures of tetrahydronitramarine,tetrahydrokomarovinine, dihydroisokomarovine,and tetrahydroisokomarovine

The alkaloid nitraraine and four new bases have been isolated for the first time from the epigeal part ofNitraria komarovii. Their structures have been established with the aid of chemical transformations and spectral characteristics: tetrahydronitramarine, tetrahydrokomarovinine, dihydroisokomarovine, and tetrahydroisokomarovine. Passages have been effected to nitramarine, komarovinine, isokomarovinine, and komarovidinine. Tetrahydroisokomarovine is a new alkaloid, while this is the first time that tetrahydronitroamarine, tetrahydrokomarovinine, and dihydroisokomarovine have been found in nature. Nitrarine, isonitrarine, and schoberidine have been isolated from the seeds with fruit.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 61–67, January–February, 1990.     

Alkaloids of Stephania delavayi IV. Isostephodeline

Summary The structure of the new alkaloid isostephodeline isolated from the roots ofStephania delavayi Diels has been established. The most probable relative configurations of isostephodeline and of the stephodeline isolated previously have been proposed.All-Union Scientific-Research Institute of Medicinal Plants. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 188–193, March–April, 1975.     

Korsinamine — A new ester alkaloid fromKorolkowia sewerzowii

Summary 1. Korsine and the new alkaloid korsinamine have been isolated from the epigeal part ofKorolkowia sewerzowii Rgl.2. On the basis of the results of a study of the IR, NMR, and mass spectra of korsinamine and also of passage to the known alkaloid korsine, the structure of korsinamine has been established as 23-O-acetylkorsine.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 233–235, March–April, 1978.     

Oxytropis alkaloids II. Structure of oxytriphine

The new alkaloid oxytriphine, the parent of natural 2-oxazoline derivatives, has been isolated from the epigeal part ofOxytropis trichophysa; and its structure has been established as (5S)-(+)-2,5-diphenyl-2-oxazoline. (-)-N-Benzoyl-2-phenyl-2-hydroxyethylamine and benzoic acid have been detected in this plant for the first time. A hypothesis of the possible biogenetic interrelationship of the compounds isolated is put forward.Institute of the Chemistry of Plant Substances. Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii. No. 6, pp. 873–876, November–December, 1993.     

Alkaloids ofDoronicum macrophyllum

Summary 1. Two known alkaloids, otosenine and floridanine, and a new alkaloid doronine have been isolated from the roots ofDoronicum macrophyllum.2. On the basis of its spectral and chemical characteristics, the structure of 6-chlorodeoxyfloridanine has been established for doronine.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. N. Narimanov Azerbaidzhan State Medical Institute, Baku. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 194–196, March–April, 1976.     

Alkaloids ofVeratrum lobelianum verdinine and 3,15-DI-O-(2-methylbutyroyl)germine

The results are given of an investigation of the alkaloid composition of the epigeal part ofVeratrum lobelianum Bernh. Veralomidine, rubijervine, germinaline, and the new bases verdinine (1) and 3,15-di-O-(2-methylbutyroyl)germine (2) were isolated. The structures of (1) and (2) have been established on the basis of their physicochemical properties and transformations. This is the first time that veralomidine has been isolated from a plant.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 100–104, January–February, 1995. Original article submitted October 17, 1994.     

Alkaloids of Aconitum coreanum VI. Structure of acoridine

The new C₂₀-diterpene alkaloid acoridine has been isolated from the epigeal part ofAconitum coreanum (Levl.) Rapaics, and the structure of 14-hydroxy-2-propionylhetisine has been established for it on the basis of spectral characteristics. Acoridine is the first diterpene alkaloid esterified by propionic acid.Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 91–93, January–February, 1991.     

Components ofHaplophyllum obtusifolium

Skimmianine, folimine, benzamide, and new alkaloid haplotusine (mp 118–119°C, C₁₁H₁₁NO₃, M⁺ 205) have been isolated from the epigeal part ofHaplophyllum obtusifolium Ledeb. growing in the environs of Kora-Koly, Turkmen SSR. By the analysis of spectral characteristics it has been established that haplotusine has the structure of 1,4-dimethoxy-2-quinolone.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 635–636, September–October, 1984.     

Alkaloids of Aconitum sajanense II. Structure of dehydroacosanine

The new alkaloid dehydroacosanine has been isolated from the roots ofAconitum sajanense Kumin, and its structure has been established by spectral and chemical methods.Institute of Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 531–534, September–October, 1992.     

8-Acetylexcelsine — A new alkaloid form Aconitum kirinense

The alkaloid 8-acetylexcelsine has been isolated from the epigeal part ofAconitum kirinense Nakai. Its structure has been established with the aid of chemical transformations and spectral characteristics.Institute of Chemistry of Plant Substances Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 258–261, March–April, 1991.     

Structure of 22-deoxocucurbitacins isolated fromBryonia alba andEcbalium elaterium

22-Deoxocucurbitacin D (II), dihydrocucurbitacin B, cucurbitacin L, and the previously unknown rhamnoglucosyl-22-deoxo-16,23-epoxycucurbitosides A (III) and B (IV) have been isolated from the roots ofBryonia alba and identified. Glucoside (III) has also been identified in the fruit ofEcbalium elaterium L.A. L. Mndzhoyan Institute of Fine Organic Chemistry, Academy of Sciences of the Armenian SSR, Erevan, Translated from Khimiya Prirodnyk Soedinenii, No. 5, pp. 679–687, September–October, 1985.     

Berberis alkaloids. XVII. Investigation of the alkaloids of Berberis heteropoda

The alkaloid composition of young shoots and leaves ofBerberis heteropoda Schrenk has been studied. In addition to known alkaloids, two new ones have been isolated — N-methyldihydroberberine and 8-oxoberberrubine, the structures of which were established by chemical transformations and a study of spectral properties. Of known alkaloids, berbamunine, aromoline, glaucine, thalicmidine, isocorydine, and reticuline have been found in this plant for the first time. Pseudopalmitine and laudanosine have been found for the first time in plants of the genusBerberis.Andizhan State Medical Institute. Institute of the Chemistry of Plant Substances of Uzbek Republic Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 53–59, January–February, 1993.