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1.
Lijun Duan Sunny N. Wallace Abigail Engelberth Justin K. Lovelady Edgar C. Clausen Jerry W. King Danielle Julie Carrier 《Applied biochemistry and biotechnology》2009,158(2):362-373
In an effort to increase revenues from a given feedstock, valuable co-products could be extracted prior to biochemical or
thermochemical conversion with subcritical water. Although subcritical water shows significant promise in replacing organic
solvents as an extraction solvent, compound degradation has been observed at elevated extraction temperatures. First order
thermal degradation kinetics from a model system, silymarin extracted from Silybum marianum, in water at pH 5.1 and 100, 120, 140, and 160 °C were investigated. Water pressure was maintained slightly above its vapor
pressure. Silymarin is a mixture of taxifolin, silichristin, silidianin, silibinin, and isosilibinin. The degradation rate
constants ranged from 0.0104 min−1 at 100 °C for silichristin to a maximum of 0.0840 min−1 at 160 °C for silybin B. Half-lives, calculated from the rate constants, ranged from a low of 6.2 min at 160 °C to a high
of 58.3 min at 100 °C, both for silichristin. The respective activation energies for the compounds ranged from 37.2 kJ/gmole
for silidianin to 45.2 kJ/gmole for silichristin. In extracting the silymarin with pure ethanol at 140 °C, no degradation
was observed. However, when extracting with ethanol/water mixtures at and 140 °C, degradation increased exponentially as the
concentration of water increased.
An erratum to this article can be found at 相似文献
2.
Extraction of nutraceuticals from milk thistle 总被引:1,自引:0,他引:1
Sunny N. Wallace Danielle Julie Carrier Edgar C. Clausen 《Applied biochemistry and biotechnology》2003,108(1-3):881-889
Milk thistle contains compounds that display hepatoxic protection properties. We examined the batch extraction of silymarin
compounds from milk thistle seed meal in 50, 70, 85, and 100°C water as a function of time. After 210 min of extraction at
100°C, the yield of taxifolin was 1.2 mg/g of seed, a 6.2-fold increase over the results obtained in a Soxhlet extraction
with ethanol on pretreated (defatted) seeds. Similarly, the yield of silychristin was 5.0 mg/g of seed, a 3.8-fold increase.
The yields of silybinin A and silybinin B were 1.8 and 3.3 mg/g of seed, respectively, or roughly 30% of the Soxhlet yield.
The ratios of the extracted compounds, and particularly the ratios at long extraction times, showed that the more polar compounds
(taxifolin and silychristin) were preferentially extracted at 85°C, while the less polar silybinin was favored at 100°C. 相似文献
3.
Carole Vincelet Jean Marc Roussel David Benanou 《Analytical and bioanalytical chemistry》2010,396(6):2285-2292
Membrane-assisted solvent extraction was applied for the determination of different classes of compounds in water, having
K
o/w (octanol–water partition coefficient) values between 101 (aniline) and 108 (methyl stearate), by means of experimental designs. Four solvents were investigated—propan-2-ol, ethyl acetate, diisopropyl
ether and cyclohexane—as well as extraction time, temperature, salt impact, pH and methanol addition. The best choice was
diisopropyl ether, 50 °C, 30 min and an addition of 3 g of sodium chloride at pH 2 for polar compounds. The relative standard
deviation (n = 3) was found in the range from 5 to 17%. Recoveries ranged between 34 and 100%. Membrane-assisted solvent extraction was
successfully applied to a fast screening method dedicated to an unknown wastewater sample. 相似文献
4.
Félix JS Monteiro M Manzoli JE Padula M Pezo D Romero J Nerín C 《Analytical and bioanalytical chemistry》2008,391(3):847-857
The aim of this work was to identify the degradation compounds produced during irradiation of multilayer polyamide 6 (PA-6)
films and to study their migration into water and 95% ethanol food simulant. After irradiation of multilayer PA-6 films at
3, 7 and 12 kGy, degradation compounds were extracted using solid-phase microextraction, for which the time and temperature
of extraction and stirring were optimized, and identified by gas chromatography–mass spectrometry. Caprolactam, 2-cyclopentylcyclopentanone
and aldehydes, among other compounds, were identified in the headspace of the films. Polydimethylsiloxane was considered the
best fiber for extraction. The optimum conditions of time, temperature and stirring to extract the compounds were 20 min,
80 °C and 225 rpm. For validation purposes, the compounds were quantified in water and 95% ethanol and the results showed
high sensitivity, good precision and accuracy. Migration of compounds from irradiated and non-irradiated multilayer PA-6 films
into water and 95% ethanol food simulants was carried out at 40 °C for 10 days. The method was efficient for the quantification
of decaldehyde, 2-cyclopentylcyclopentanone and caprolactam that migrated from multilayer PA-6 films into food simulants. 相似文献
5.
《Journal of separation science》2005,28(13):1485-1492
SPE is a commonly applied technique for preconcentration of pesticides from water samples. Microwave‐assisted extraction (MAE) technique is the extraction applied for preconcentration of different compounds from solid samples. SPE coupled with MAE is capable of preconcentrating these compounds from water samples too. This investigation was aimed at improving the efficiency of atrazine, alachlor, and α‐cypermethrin pesticide extraction from the spiked water samples applying SPE followed by MAE. In this way, MAE served for elution of pesticides from C18‐extraction disks with solvent heated by microwave energy. Various elution conditions were tested for their effects on the extraction efficiency of the SPE–MAE combined technique. Several parameters, such as elution solvent volume (mL), elution temperature (°C), and duration of elution (min), affect the extraction efficiency of the SPE–MAE coupled system and need to be optimized for the selected pesticides. In order to develop a mathematical model, 15 experiments were performed in the central composite design. The equation was then used to predict recoveries of the pesticides under specific experimental conditions. Optimization of microwave extraction was accomplished using the genetic algorithm approach. Best results were achieved using 20 mL of ethanol at 60°C. Optimal hold time was 5 min and 24 s. The SPE–MAE combination was also compared with the conventional SPE extraction technique with elution of a nonpolar or a moderately polar compound with nonpolar solvents. 相似文献
6.
A thermochemical pretreatment of bagasse for the enzymatic hydrolysis has been carried out, in which pretreatment bagasse
was autoclaved with binary solvent, composed of Water and organic solvent having upper critical temperature (UCT) on the mutual
solubility curve. The pretreatment was named “UCT-solvent pretreatment.” The hydrophobic decomposition products from lignin
and hemicellulose, that dissolved in organic phase at room temperature, could be easily separated from the solid and sugars
in the aqueous phase. By using UCT-solvent instead of only water, the sugar recoveries from bagasse through the pretreatment
and the enzymatic hydrolysis were much improved. There exists an optimal mixing ratio between organic solvent and water to
maximize the effect of the pretreatment for enzymatic hydrolysis. The optimal ratio can be explained by the competitive effect
between the ability of water as a reagent for the hydrolysis and the ability of solvent for the extraction of the decomposition
product, and furthermore by the competitive effect between affinities of the solvent to hydrophilic hemicellulose and hydrophobic
lignin. Decomposition of hemicellulose at lower temperature than 190°C was decreased, and hence the degradation of xylose
during the pretreatment decreased. These favorable effects of UCT-solvent pretreatment are significantly attributed to the
formation of the homogeneous single phase of organic solvent and water at high temperature and the phase separation at room
temperature. 相似文献
7.
H. Bayram M. Önal G. Üstünışık Y. Sarıkaya 《Journal of Thermal Analysis and Calorimetry》2007,89(1):169-174
An industrial raw material taken from Sivrihisar (Eskişehir, Turkey) region was heat-treated at different temperatures in
the range of 100–1000°C for 2 h. The volumetric percentage of the particles having a diameter below 2 μm after staying in
an aqueous suspension of the material was determined as 67% by the particle size distribution analysis. The mineralogical
composition of the material was obtained as mass% of 32% palygorskite, 10% metahalloysite, 35% magnesite, 20% dolomite and
3% interparticle water by using the acid treatment, X-ray diffraction and thermal analysis (TG, DTA) data.
The temperature ranges were determined for the endothermic dehydrations for the interparticle water as 25–140°C, for the zeolitic
water as 140–320°C, and for the bound water as 320–480°C, in the palygorskite. The temperature range for the endothermic dehydroxylation
and exothermic recrystalization of the palygorskite is 780–840°C. The temperature range for the endothermic dehydroxylation
of the metahalloysite and calcinations of magnesite are coincided at 480–600°C. Dolomite calcined in the temperature range
of 600–1000°C by two steps. The zig-zag changes in the specific surface area (S/m2 g−1) and specific micro and mesopore volume (V/cm3 g−1) as the temperature increases were discussed according to the dehydrations in the palygorkskite, dehydroxylation of palygorskite
and metahalloysite, and calcinations in magnesite and dolomite. 相似文献
8.
Moreira MM Morais S Barros AA Delerue-Matos C Guido LF 《Analytical and bioanalytical chemistry》2012,403(4):1019-1029
This paper reports a novel application of microwave-assisted extraction (MAE) of polyphenols from brewer’s spent grains (BSG).
A 24 orthogonal composite design was used to obtain the optimal conditions of MAE. The influence of the MAE operational parameters
(extraction time, temperature, solvent volume and stirring speed) on the extraction yield of ferulic acid was investigated
through response surface methodology. The results showed that the optimal conditions were 15 min extraction time, 100 °C extraction
temperature, 20 mL of solvent, and maximum stirring speed. Under these conditions, the yield of ferulic acid was 1.31 ± 0.04%
(w/w), which was fivefold higher than that obtained with conventional solid–liquid extraction techniques. The developed new extraction
method considerably reduces extraction time, energy and solvent consumption, while generating fewer wastes. HPLC-DAD-MS analysis
indicated that other hydroxycinnamic acids and several ferulic acid dehydrodimers, as well as one dehydrotrimer were also
present, confirming that BSG is a valuable source of antioxidant compounds. 相似文献
9.
《Arabian Journal of Chemistry》2022,15(3):103666
Calophyllum inophyllum has been known as a part of the mangrove forest area. This species is distributed primarily in the coastal regions of Indonesia and Africa. It is rich in bioactive compounds and has been used as a traditional medication. This work employed a single replicate of the one-factor-at-a-time experiment method to investigate optimum conditions, which resulted in the highest TPC. The three factors studied were organic solvent type (acetone, ethanol, and methanol), organic solvent concentration in water (50–100%, v/v), and extraction temperature (30–60 °C). The extraction was conducted with the percolation method. The result shows that organic solvent type, organic solvent concentration in water, and extraction temperature significantly affect the TPC, TFC, and the yield of crude extract obtained. The highest TPC (289.12 mg GAE/g of the residue of C. inophyllum leaves) was achieved with 80% methanol in water at 30 °C for 48 h. Under this condition, TFC value of 410.4 mg QE/g of the residue of C. inophyllum leaves, the yield of 2.41%, and IC50 value of 0.054 µg/mL were achieved. Moreover, bis (2-ethylhexyl) phthalate was firstly detected in the extract. 相似文献
10.
Yu Seung Kim Feng Wang Michael Hickner Stephan Mccartney Young Taik Hong William Harrison Thomas A. Zawodzinski James E. Mcgrath 《Journal of Polymer Science.Polymer Physics》2003,41(22):2816-2828
Directly copolymerized wholly aromatic sulfonated poly(arylene ether sulfone) copolymers derived from 4,4′‐biphenol, 4,4′‐dichlorodiphenyl sulfone, 3,3′‐disulfonated, and 4,4′‐dichlorodiphenyl sulfone (BPSH) were evaluated as proton‐exchange membranes for elevated temperature operation (100–140 °C). Acidification of the copolymer from the sulfonated form after the nucleophilic step (condensation) copolymerization involved either immersing the solvent‐cast membrane in sulfuric acid at 30 °C for 24 h and washing with water at 30 °C for 24 h (method 1) or immersion in sulfuric acid at 100 °C for 2 h followed by similar water treatment at 100 °C for 2 h (method 2). The fully hydrated BPSH membranes treated by method 2 exhibited higher proton conductivity, greater water absorption, and less temperature dependence on proton conductivity as compared with the membranes acidified at 30 °C. In contrast, the conductivity and water absorption of a control perfluorosulfonic acid copolymer (Nafion 1135) were invariant with treatment temperature; however, the conductivity of the Nafion membranes at elevated temperature was strongly dependent on heating rate or temperature. Tapping‐mode atomic force microscope results demonstrated that all of the membranes exposed to high‐temperature conditions underwent an irreversible change of the ionic domain microstructure, the extent of which depended on the concentration of sulfonic acid sites in the BPSH system. The effect of aging membranes based on BPSH and Nafion at elevated temperature on proton conductivity is also discussed. © 2003 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 41: 2816–2828, 2003 相似文献
11.
J. David Pinkston Thomas E. Delaney Donald J. Bowling Thomas L. Chester 《Journal of separation science》1991,14(6):401-406
Components of hamster feces ranging from low molecular weight fatty acids through the expected range of triglycerides have been eluted in a single SFC run with simultaneous pressure and temperature programming. Temperature programming from 140°C to 240°C was required to provide optimum conditions for separation of the fatty acids and to move the elution region of the sterol esters away from that of the triglycerides. Data from chemical ionization and electron impact mass spectrometry of compounds separated by SFC were used to confirm identities suggested by retention measurements and to provide tentative identities of unknown compounds. SFC with flame ionization detection was used to compare Soxhlet extraction, off-line supercritical fluid extraction (SFE), and on-line SFE of the feces. Although samples obtained by Soxhlet extraction and SFE produced very similar chromatograms, SFE required far less time and consumed much smaller quantities of organic solvent. 相似文献
12.
Olivella MA 《Analytical and bioanalytical chemistry》2005,383(1):107-114
An analytical procedure based on extraction by accelerated solvent extraction (ASE) followed by gas chromatography–mass spectrometry
(GC/MS) analysis has been developed for the determination of particulate polycyclic aromatic hydrocarbons (PAHs) from large-volume
water samples (20 L). The effect of temperature and number of cycles on the efficiency of ASE was investigated: the best results
were obtained by using a temperature of 100°C and one static cycle. A mixture of hexane/acetone 1:1 (v/v) was used as extraction
solvent. Mean total method recovery under optimized conditions was 85%. The developed methodology was applied to the analysis
of suspended particulate matter from Lake Maggiore waters (north of Italy). Mean PAH concentrations in suspended particulate
matter from Lake Maggiore ranged from 0.2 ng L−1 for anthracene to 18.7 ng L−1 for naphthalene. 相似文献
13.
In this study a laboratory-made superheated water system was applied in order to extract some pesticides from sand, sediment
and soil samples. Extraction efficiencies were investigated at different time intervals with regard to temperature, type and
amount of organic modifier. Pesticides were removed from the aqueous extract using dichloromethane as a trapping solvent.
The optimal extraction temperature from sand specimens for malathion, heptachlor, aldrin, dieldrin, butachlor, metalaxyl and
propiconazole was found to be 160 °C, while those for chlordane and thiobencarb were 120 °C and 180 °C, respectively. The
static extraction time for heptachlor, aldrin, dieldrin, butachlor and metalaxyl was found to be 15 min, whereas for malathion
and thiobencarb it was 5 min, and for chlordane and propiconazole it was 10 and 20 min, respectively. Recoveries for the extractions
of the pesticides from sand under optimized extraction conditions ranged between 96 and 101%. Those obtained from sediment
under such conditions were unsatisfactory, and were consequently improved by adding an organic modifier to the superheated
water, and sodium chloride to the extract during liquid-liquid extraction. These procedures were optimized further for the
parameters described and recoveries exceeded 91%, with the exception of butachlor. The extraction technique was also applied
to soil samples at a reduced water flow rate of 0.5 mL min−1, yielding recoveries of 82–105%, and 76% for dieldrin. The reproducibilities, expressed as relative standard deviations (RSDs),
ranged between 2 and 13%. 相似文献
14.
Qiusheng Yang Xue Yang Yanji Wang Haiou Wang Qingyan Cheng 《Research on Chemical Intermediates》2012,38(9):2277-2284
Effective hydrolysis of cyclohexene oxide (CHO) was conducted by heating in water between 100 and 140?°C without another catalyst. It provided 100?% purity and 100?% yield of trans-1,2-cyclohexanediol (1,2-CHD) with five times of H2O to CHO at 120?°C for 6?h. These intermediates of polyether polyols could be totally decomposed to 1,2-CHD (monomer) by hot water under the same condition. The improved process eliminates the purification and markedly reduces the cost of 1,2-CHD in the follow-up industrial production. The main factors, such as reaction temperature, time, and water volume, were investigated. It was proposed that water acted as a modest acid catalyst, reactant, and solvent in the hydrolysis of CHO and polymers. 相似文献
15.
Pól J Varadová Ostrá E Karásek P Roth M Benesová K Kotlaríková P Cáslavský J 《Analytical and bioanalytical chemistry》2007,388(8):1847-1857
Pressurised fluid extraction using water or methanol was employed for the extraction of stevioside from Stevia rebaudiana Bertoni. The extraction method was optimised in terms of temperature and duration of the static or the dynamic step. Extracts
were analysed by liquid chromatography followed by UV and mass-spectrometric (MS) detections. Thermal degradation of stevioside
was the same in both solvents within the range 70–160 °C. Methanol showed better extraction ability for isolation of stevioside
from Stevia rebaudiana leaves than water within the range 110–160 °C. However, water represents the green alternative to methanol. The limit of
detection of stevioside in the extract analysed was 30 ng for UV detection and 2 ng for MS detection. 相似文献
16.
《Arabian Journal of Chemistry》2022,15(2):103597
Phenolic compounds are bioactive compounds that are also naturally found in red algae. To determine the level of these compounds in the red algae, spectroscopic or chromatographic determination was applied over the liquid extracts. Therefore, a prior extraction method is needed. The presented study aimed to develop the analytical ultrasound-assisted extraction (UAE) method to extract phenolic compounds from red algae. A Box–Behnken design (BBD) based on five factors included solvent composition (50–90% ethanol in water), extraction temperature (10–60 °C), ultrasonic power (20–100%), pulse duty-cycle (0.2–1.0 s?1), and solvent-to-sample ratio (10:1 to 30:1) was used to evaluate the effects of the studied factors. Subsequently, response surface methodology (RSM) was performed to define the optimum extraction condition to recover phenolic compounds from the alga matrices. The UAE condition suggested by RSM was: ultrasonic power 100%, pulse duty-cycle 1 s?1, temperature 52.5 °C, extraction solvent 50% ethanol in water, and solvent-to-sample ratio 30:1. Kinetic studies confirmed 10 min to provide comparable recovery (p > 0.05) than any longer extraction time. The acceptable values validated the developed method for repeatability (CV, 4.8%) and intermediate precision (CV, 5.7%). In addition, the accuracy of the method suggested a complete recovery for two extraction cycles. Furthermore, the method has successfully been applied for a number of samples covering three different red algae species. Fingerprints of each sample based on phenolic composition and levels characterize the type and origin of different red algae species. 相似文献
17.
Andreas Ammann Dirk C. Hinz R. Shane Addleman Chien M. Wai B. W. Wenclawiak 《Fresenius' Journal of Analytical Chemistry》1999,364(7):650-653
Superheated water extraction, steam distillation and supercritical fluid extraction (SFE) are compared for extraction of
l-menthol, menthone, eucalyptol and other components of peppermint (mentha piperita) leaves. Different temperatures and pressures were investigated. SFE results at 25/40 °C and 6.5/8/10 MPa were comparable
with those reported in the literature. Although SFE is a gentle way of extracting thermally unstable compounds, this method
is too slow for commercial use in comparison with steam distillation at 100 °C. Superheated water extraction at 125/150 °C
and 1–2 MPa exhibits higher extraction efficiency than the SFE method. Comparison of all experiments under the chosen conditions
shows steam distillation to be the most effective extraction method.
Received: 18 January 1998 / Revised: 9 April 1999 / Accepted: 15 April 1999 相似文献
18.
Lourdes Casas Casimiro Mantell Miguel Rodríguez Ascensión Torres Francisco A. Macías Enrique J. Martínez de la Ossa 《Journal of separation science》2009,32(9):1445-1453
The kinetics of the supercritical fluid extraction of bioactive compounds from sunflower using CO2 as solvent were studied in order to establish an efficient method for this extraction. The influence of time of extraction at different solvent flow rates was investigated. The extraction pressure and temperature were optimized in previous studies and these values used were 400 bar and 50°C. The extraction yields and the bioactivity levels of the extracts were also analysed. The results indicate that the most appropriate extraction time is between 120 and 180 min depending on the solvent flow and the pretreatment of the sample. The dried sample extracted at 40 g/min, the congealed sample extracted at the same flow and 180 min, and the dried sample extracted at 25 g/min for 120 min showed the best activity profiles. The extractions were carried out in a pilot plant with an extraction vessel with a capacity of 2 L. 相似文献
19.
Elenise Bannwart de Moraes Patricia Fazzio Martins César Benedito Batistella Mario Eusebio Torres Alvarez Rubens Maciel Filho Maria Regina Wolf Maciel 《Applied biochemistry and biotechnology》2006,132(1-3):1066-1076
Molecular distillation was studied for the separation of tocopherols from soya sludge, both experimentally and by simulation,
under different operating conditions, with good agreement. Evaporator temperatures varied from 100°C to 160°C and feed flow
rates ranged from 0.1 to 0.8 kg/h. The process pressure was maintained at 10−6 bar, the feed temperature at 50°C, the condenser temperature at 60°C, and the stirring at 350 rpm. For each process condition,
samples of both streams (distillate and residue) were collected and stored at −18°C before tocopherols analyses. Owing to
the differences between molecular weights and vapor pressures of free fatty acids and tocopherols, tocopherols preferentially
remained in the residue at evaporator temperatures of 100°C and 120°C, whereas for higher temperatures (140°C and 160°C) and
lower feed flow rate, tocopherols tended to migrate to the distillate stream. 相似文献
20.
Wei Li Zhengbo Liu Zi Wang Li Chen Yinshi Sun Jingang Hou Yinan Zheng 《Journal of separation science》2010,33(12):1870-1876
Accelerated solvent extraction (ASE) was applied to the extraction of saikosaponin a, saikosaponin c and saikosaponin d from the roots of Bupleurum falcatum. Main extraction parameters such as the extraction solvents, extraction temperature and static extraction time were investigated and optimized. The optimized procedure employed 70% methanol as extraction solvent, 120°C of extraction temperature, 10 min of static extraction time, 60% of flush volume and the extraction recoveries of the three compounds were near to 100% with one extraction cycle. The extracted samples were analyzed by HPLC with UV detector. The HPLC conditions were as follows: Hypersil ODS2 (4.6 mm×250 mm, 5 μm) column, acetonitrile and water as mobile phase, flow rate of 1.0 mL/min, UV detection wavelength of 204 nm and injection volume of 20 μL. Compared with the traditional methods including heat‐reflux extraction and ultrasonic‐assisted extraction, the proposed ASE method was more efficient and faster to be operated. The results indicated that ASE was an alternative method for extracting saikosaponins from the roots of B. falcatum. 相似文献