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Floccosic Acid,a New Triterpenic Acid from Nepeta floccosa
Authors:Liaqat Ali  Samina Ali  Javid Hussain  Ahmed Al‐Harrasi  Abdul Latif?Khan  Syed Tasleem?Hussain?Shah  Tania Shamim?Rizvi
Affiliation:1. Department of Biological Sciences and Chemistry, College of Arts and Sciences, University of Nizwa, Birkat Al‐Mouz, Nizwa 616, Sultanate of Oman, (phone: +968‐25446608;2. fax: +968‐25446289);3. Department of Chemistry, Kohat University of Science & Technology, Kohat 26000, KPK, Pakistan;4. National Nematological Research Center, University of Karachi, Karachi‐75270, Pakistan
Abstract:The isolation and structure elucidation of a new triterpenic acid named floccosic acid ( 1 ) is reported on the basis of the 1D‐ and 2D‐NMR assignments. This secondary metabolite was isolated as a new constituent, along with the known triterpenoids, betulinic acid and β‐amyrin. All these compounds were purified by repeated column chromatography of the MeOH extract of Nepeta floccosa. The structure elucidation of the new compound was accomplished by the combined mass spectrometry (MS), infrared (IR) and ultraviolet (UV) absorption spectroscopy, one‐ (1H‐ and 13C‐) and two‐dimensional (H? C correlations; HMBC and HSQC) NMR techniques. The known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature.
Keywords:Nepeta floccosa  Floccosic acid  Metabolites
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