Tirucallane‐Type Triterpenoids from Celastrus stylosus Wall. |
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| Authors: | Wei‐Guang Shan Zai‐Lin Gao You‐Min Ying Jia‐Gui Xiang Fa‐Song Wang Zha‐Jun Zhan |
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| Affiliation: | 1. College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P.?R. China, (phone/fax: +86‐571‐88871075);2. Zhejiang CONBA Pharmaceutical & Drug Research Development Corporation, Hangzhou 310052, P.?R. China;3. Zhejiang Key Laboratory for Traditional Chinese Medicine, Pharmaceutical Technology, Hangzhou 310052, P.?R. China;4. Key Laboratory of Biologic Resources Protection and Utilization of Hubei Province and College of Chemistry and Environmental Engineering, Hubei University for Nationalities, Enshi 445000, P.?R. China |
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| Abstract: | Two new tirucallane‐type triterpenoids, (24Z)‐tirucalla‐7,24‐diene‐3β,11β,26‐triol ( 1 ) and (3S,24R)‐tirucall‐7‐ene‐3,24,25‐triol ( 2 ), along with the known compound celastrol ( 3 ), were isolated from the root barks of Celastrus stylosus Wall . The structures of 1 – 3 were established by spectroscopic methods, including extensive 2D NMR and MS analyses. It is the first report on tirucallane‐type triterpenoids from the genus Celastrus and may be of vital chemotaxonomic significance. |
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| Keywords: | Celastrus stylosus Tirucallane Triterpenoids Chemotaxonomy |
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