Heterocycles from α‐Aminonitriles |
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| Authors: | Nicola Otto Prof?Dr Till Opatz |
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| Affiliation: | Institute of Organic Chemistry, Johannes Gutenberg University of Mainz, Duesbergweg 10–14, Mainz (Germany) |
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| Abstract: | Owing to their various modes of reactivity, α‐aminonitriles represent versatile building blocks for the construction of a wide range of nitrogen heterocycles. The present Concept article focuses on synthetic methodologies using their bifunctional nature which is the basis of their reactivity as α‐amino carbanions and as iminium ions. Reactions exclusively taking place on either the amine or on the nitrile moiety will not be considered. |
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| Keywords: | α ‐aminonitriles heterocycles nitrogen heterocycles synthetic methods |
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