| 超声辅助萃取气相色谱-三重四极杆质谱法测定室内灰尘中的39种多氯联苯 |
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| 引用本文： | 王炳玲,张晓玲,张琦,陆晓梅,崔媛,张正东.超声辅助萃取气相色谱-三重四极杆质谱法测定室内灰尘中的39种多氯联苯[J].色谱,2014,32(1):74-80. |
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| 作者姓名： | 王炳玲 张晓玲 张琦 陆晓梅 崔媛 张正东 |
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| 作者单位： | 1. 南京医科大学公共卫生学院卫生检验学系, 江苏 南京 211166;
2. 南京医科大学公共卫生学院职业医学与 环境卫生学系, 江苏 南京 211166;
3. 青岛市疾病预防控制中心, 山东 青岛 266033 |
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| 基金项目： | 国家自然科学基金面上项目(81072268);江苏省自然科学基金面上项目(BK2010535);江苏省博士后基金(1001017C);江苏高校优势学科建设工程项目 |
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| 摘 要： | 建立了测定室内灰尘样品中39种多氯联苯(PCBs)的分析方法。样品经吸尘器采集、正己烷-二氯甲烷(1：1，v/v)超声萃取、浓缩后，利用气相色谱-三重四极杆质谱法(GC-MS/MS)在选择反应监测(SRM)模式下测定。结果表明，39种PCBs在30 min内得到了很好的分离，在0.1~100 μg/L范围内线性关系良好，相关系数为0.9910~0.9999，方法的加标回收率为57.2%~120.3%，日内测定的相对标准偏差(RSD)为0.3%~24.7%，日间测定的RSD为0.6%~29.9%，检出限(信噪比为3)为0.0003~0.2080 ng/g。本方法灵敏度高、准确度和精密度好，简便快速，溶剂消耗量少，适用于灰尘中多种多氯联苯的同时测定。
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| 关 键 词： | 多氯联苯 气相色谱-串联质谱 室内灰尘 |
| 收稿时间： | 2013-09-06 |
Determination of 39 polychlorinated biphenyls in indoor dust using ultrasonic extraction and gas chromatography-tandem mass spectrometry |
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| WANG Bingling;ZHANG Xiaoling;ZHANG Qi;LU Xiaomei;CUI Yuan;ZHANG Zhengdong.Determination of 39 polychlorinated biphenyls in indoor dust using ultrasonic extraction and gas chromatography-tandem mass spectrometry[J].Chinese Journal of Chromatography,2014,32(1):74-80. |
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| Authors: | WANG Bingling;ZHANG Xiaoling;ZHANG Qi;LU Xiaomei;CUI Yuan;ZHANG Zhengdong |
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| Affiliation: | 1. Department of Hygienic Analysis and Detection of School of Public Health, Nanjing Medical University, Nanjing 211166, China;
2. Department of Occupational Medicine and Environmental Health of School of Public Health, Nanjing Medical University, Nanjing 211166, China;
3. Qingdao Municipal Center for Disease Control and Prevention, Qingdao 266033, China |
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| Abstract: | A method for the determination of 39 polychlorinated biphenyls (PCBs) in indoor dust was developed. A vacuum cleaner was used for gathering the house dust. N-Hexane-dichloromethane (1:1, v/v) was added and the extraction was performed in an ultrasonic bath. The supernatant was concentrated and then 0.1 mL n-hexane-dichloromethane (1:1, v/v) was added. Gas chromatography-tandem mass spectrometry (GC-MS/MS) in selected-reaction monitoring (SRM) mode has been investigated for the determination of the 39 PCBs congeners in indoor dust. The 39 PCBs had highly efficient separation within 30 min and showed good linearity in the range of 0.1-100 μg/L with the correlation coefficients of 0.9910-0.9999. The spiked recoveries were 57.2%-120.3%. The intra-day relative standard deviations (RSDs) were between 0.3% and 24.7%, while the inter-day RSDs were between 0.6% and 29.9%. This method has good linearity, high sensitivity, high accuracy and precision. Also, it is simple, rapid and low solvent consumption. The low chemical background interference allowed it to be used in more complex matrices. |
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| Keywords: | gas chromatography-tandem mass spectrometry (GC-MS/MS) polychlorinated biphenyls (PCBs) indoor dust |
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