| 贻贝中有机氯农药和多氯联苯标准物质的研制及同位素稀释高分辨质谱法定值 |
| |
| 引用本文： | 卢宪波,陈吉平,王淑秋,邹黎黎,田玉增,倪余文,苏凡.贻贝中有机氯农药和多氯联苯标准物质的研制及同位素稀释高分辨质谱法定值[J].色谱,2012,30(9):915-921. |
| |
| 作者姓名： | 卢宪波 陈吉平 王淑秋 邹黎黎 田玉增 倪余文 苏凡 |
| |
| 作者单位： | 中国科学院大连化学物理研究所, 辽宁 大连 116023 |
| |
| 基金项目： | 国家“863”计划项目(2009AA061603);国家“973”计划项目(2009CB421602) |
| |
| 摘 要： | 建立了贻贝中有机氯农药(OCPs)和多氯联苯(PCBs)标准物质的研制和定值方法,该研究对我国开展环境生物标准物质的研制具有重要的方法学借鉴价值。该标准物质样品为采自大连湾海域的贻贝,其定值目标物包括18种OCPs和16种PCBs,采用的定值测量方法是目前世界上最权威、最准确的同位素稀释-高分辨气相色谱/高分辨质谱联用法(ID-HRGC/HRMS)。所研制的标准物质具有定值目标物种类多、不确定度较小(约10%)等特点。该标准物质是目前国际上唯一一种采用同位素稀释高分辨质谱法进行定值的底栖生物中OCPs标准物质,于2012年3月通过了国家一级标准物质的终审,并于2012年6月被国家质量监督检验检疫总局批准为国家一级标准物质(GBW10069)。该标准物质可用于食品安全控制、环境监测、质量检测等领域相关分析方法的评价、测量质量控制及技术仲裁检验等。
|
| 关 键 词： | 高分辨气相色谱/高分辨质谱 同位素稀释质谱法 有机氯农药 多氯联苯 贻贝 环境标准物质 |
| 收稿时间： | 2012-04-25 |
Preparation and certification of mussel reference material for organochlorine pesticides and polychlorinated biphenyls using isotope dilution-high resolution mass spectrometry |
| |
| LU Xianbo,CHEN Jiping,WANG Shuqiu,ZOU Lili,TIAN Yuzeng,NI Yuwen,SU Fan.Preparation and certification of mussel reference material for organochlorine pesticides and polychlorinated biphenyls using isotope dilution-high resolution mass spectrometry[J].Chinese Journal of Chromatography,2012,30(9):915-921. |
| |
| Authors: | LU Xianbo CHEN Jiping WANG Shuqiu ZOU Lili TIAN Yuzeng NI Yuwen SU Fan |
| |
| Affiliation: | (Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China |
| |
| Abstract: | A method for the preparation and certification of the reference material of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in mussel tissue is described. The mussel tissue from Dalian Bay was frozen-dried, comminuted, sieved, homogenized, packaged, and sterilized by 60Co radiation sterilization in turn. The certified values for 18 OCPs and 16 PCBs were determined by high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS) using isotope dilution and internal standard quantitation techniques. The certified values were validated and given based on seven accredited laboratories, and these values are traceable to the SI (international system of units) through gravimetrically prepared standards of established purity and measurement intercomparisons. The certified values of PCBs and OCPs in mussel span 4 orders of magnitude with a relative uncertainty of about 10%. This material is a natural biological material with confirmed good homogeneity and stability, and it was approved as the grade “primary reference material” (GBW10069) in June 2012 in China. This reference material provided necessary quality control products for our country to implement the Stockholm Treaty on the monitoring of persistent organic pollutants (POPs). The material is intended to be used for the method validation and quality control in the determination of OCPs and PCBs in biota samples. |
| |
| Keywords: | high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS) isotope dilution mass spectrometry (IDMS) organochlorine pesticides (OCPs) polychlorinated biphenyls (PCBs) mussel environmental reference material |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《色谱》浏览原始摘要信息 |
|
点击此处可从《色谱》下载全文 |
