| An electromagnetic view of relay time in propagation of neural signals |
| |
| 作者姓名： | 徐晶晶 徐三津 王帆 许胜勇 |
| |
| 作者单位： | School of Microelectronics;Department of Electronics |
| |
| 基金项目： | Project supported by the National Key Research and Development Program of China(Grant Nos.2017YFA0701302 and 2016YFA0200802);the Fundamental Research Funds of Shandong University,China(Grant No.2018GN030)。 |
| |
| 摘 要： | We review the experimental and computational data about the propagation of neural signals in myelinated axons in mice,cats,rabbits,and frogs published in the past five decades.In contrast to the natural assumption that neural signals occur one by one in time and in space,we figure out that neural signals are highly overlapped in time between neighboring nodes.This phenomenon was occasionally illustrated in some early reports,but seemed to have been overlooked for some time.The shift in time between two successive neural signals from neighboring nodes,defined as relay timeτ,was calculated to be only 16.3μs-87.0μs,i.e.,0.8%-4.4%of the average duration of an action potential peak(roughly 2 ms).We present a clearer picture of the exact physical process about how the information transmits along a myelinated axon,rather than a whole action potential peak,what is transmitted is only a rising electric field caused by transmembrane ion flows.Here in the paper,τrepresents the waiting time until the neighboring node senses an attenuated electric field reaching the threshold to trigger the open state.The mechanisms addressed in this work have the potential to be universal,and may hold clues to revealing the exact triggering processes of voltage-gated ion channels and various brain functions.
|
| 关 键 词： | neural signal relay propagation velocity electromagnetic field model ion channels |
An electromagnetic view of relay time in propagation of neural signals |
| |
| Jing-Jing Xu,San-Jin Xu,Fan Wang,Sheng-Yong Xu.An electromagnetic view of relay time in propagation of neural signals[J].Chinese Physics B,2021(2). |
| |
| Authors: | Jing-Jing Xu San-Jin Xu Fan Wang Sheng-Yong Xu |
| |
| Affiliation: | (School of Microelectronics,Shandong University,Ji'nan 250100,China;Department of Electronics,School of Electronics Engineering and Computer Science,Peking University,Beijing 100871,China) |
| |
| Abstract: | |
| |
| Keywords: | |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
