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Recent Advances in Graphene Quantum Dots for Fluorescence Bioimaging from Cells through Tissues to Animals
Authors:Dan Wang  Jian‐Feng Chen  Liming Dai
Affiliation:1. State Key Laboratory of Organic‐Inorganic Composites, Beijing University of Chemical Technology, Beijing, China;2. Center of Advanced Science and Engineering for Carbon (Case4Carbon), Department of Macromolecular Science and Engineering, Case School of Engineering, Case Western Reserve University, Cleveland, OH, USA
Abstract:Graphene quantum dots (GQDs) have attracted tremendous attention in recent years. In this review, the recent developments are summarized in the synthesis, edge functionalization, and cyctotoxicity of GQDs, followed by presenting a focused overview on their current applications for in vitro fluorescence imaging in cells and tissues as well as in vivo macroscopic and microscopic imaging in animals. Challenges and opportunities in the development of GQDs for bioimaging are also discussed.
Keywords:fluorescence bioimaging  graphene quantum dots  in vitro  in vivo  therapy
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